猴痘多国疫情，外部情况报告第63号-2026年2月24日

Multi-countryexternalsituationreportno.63,published24February2026 Highlights •Transmission of mpox continues insexual networks, affecting both women and men, and in some historicallyendemic areas.All clades ofmonkeypox virus(MPXV)continuetocirculate.Unlessmpox outbreaks arerapidlycontained and human-to-human transmission isinterrupted, thereisa risk of sustained communitytransmission. •InJanuary 2026,50countries acrossallWHO regionsreporteda total of1334newconfirmedmpoxcases,includingthreedeaths (case fatality ratio [CFR] 0.2%).Ofthese cases,66%werereportedinthe African Region.•Fourregionsobservedadeclineinconfirmedcases inJanuary,compared toDecember2025, while theEuropeanRegionreportedan increase in confirmed cases.•Twentycountries in Africareportedactive transmission of mpox in the last six weeks(5 January–15 February2026), with1142confirmed cases, includingfourdeaths (CFR0.4%).Countries reporting the highest number ofcasesin this period are the Democratic Republic of the Congo,Guinea,Madagascar,LiberiaandGhana.•One country,Comoros,andoneterritory,La Réunion (OverseasDepartment of France),have reported mpox dueto clade Ib MPXV for the first time.•Outside Africa,reports ofcommunitytransmission of clade Ib MPXVcontinueinFrance,Portugaland Spain,includinginsexualnetworks of men who have sex with men.•WHO conductedaglobal mpox rapid risk assessment in February 2026;theoverall globalpublic health riskassociatedwith the mpox multi-country outbreakwas assessedas moderate.•India has reportedacase ofmpoxwith the cladeIb /IIbrecombinantMPXV.Thestrainsequencedisclosely relatedtothefirstclade Ib/IIb recombinantstrainreported by theUnited Kingdom of Great Britain and Northern Irelandin December 2025.As both cases are travel-related, these case reportssuggestwidertransmission of therecombinant strain, implicating four countries inthree WHO regions. Epidemiological update Thissituation report includesthe most relevantnewinformationonmpox outbreaks and response activities.Detailedepidemiologicalanalyses anddataare availablein theWHO mpox surveillance report. Global monkeypox virus (MPXV) distribution Since thelastsituation report,andas of15 February2026,one country,Comoros,and one territory,LaRéunion(Overseas Department of France),havereported mpox due to clade Ib MPXV for the first time(Figure 1).Forboth,this isalsothefirsttime they havereportedmpox cases.Detailed informationonclade-specifictransmissiondynamicscan be found in thesituation report#53. Figure 1.Geographic distribution of MPXVclades1reported to WHO, by country, 1 January 2022 to15February2026.2 Reporting ofcommunity transmission of clade Ib MPXV3outside Central and East Africa(Figure 2)continuesin theWHO European Region, inFrance,Portugaland Spain, includingin,but not limited to,sexual networksof men whohave sex withmen.Since thelast editionof thisreport,oneadditionalcountryin the WHO European Region,Portugal, hasreportedcommunity transmission of clade IbMPXV. Global situation Global surveillancedataareupdatedmonthly;datapresented here areas of31January2026. InJanuary 2026,50countriesreported1334confirmed cases(Figure 3), includingthreedeaths (case fatality ratio[CFR] 0.2%)5. The countries with the highest number of confirmed cases in the last month are in theWHOAfrican Region (Figure3), which reported66% (881of 1334) of confirmed cases inJanuary2026.TheWHO African Regionhas beenreportingan overalldownward trend in confirmed mpox casesfollowing the peak in May 2025, withmonthlyconfirmed case counts remaining stableoverthe last two months(Figure 4).More details can be found in theAfricasection. TheEuropean Regionreported a 67% increase in confirmedcases (from 129 to216confirmed cases) in January2026, compared to December 2025. FourWHOregionsobservedadeclineinreportedconfirmedcasesinJanuary 2026compared toDecember 2025:the Eastern Mediterranean Region(75%,fromfour tooneconfirmed case),theRegionof the Americas(54%,from376to 172confirmed cases),theWestern PacificRegion,(46%,from90to49confirmed cases), andthe South-East Asia Region (12%,from17 to15confirmed cases). Situation in Africa This sectionreports on dataprovidedasof15February2026. From 1 January2025to15 February2026,30countries in Africa reported45 726confirmed mpox cases,including203deaths(CFR0.4%).Twentycountrieson the continenthavereportedactive transmission of mpox in the lastsixweeks(Figure5), with1142confirmed cases, includingfourdeaths (CFR 0.4%),during this period.Countriesreporting the highest number ofconfirmedcasesover the last six weeksare the Democratic Republic of the Congo(367 confirmed cases),Madagascar(332),Guinea(104),Liberia(96),andGhana(50).Thesecountries have beenreporting overall downwardtrendsin confirmed casesin recent weeks. Overall,weeklyreportedconfirmed cases continue to declineonthe continent, withfewer than 300 new confirmedcases reportedper weekrecently(Figure 6).Datafor the most recent weeks should be interpreted with caution,as reporting delays often le