猴痘多国爆发，外部情况报告第62号-2026年1月23日

Multi-countryexternalsituationreportno.62,published23January2026 Highlights •All clades ofmonkeypox virus (MPXV)continuetocirculate.Unlessmpox outbreaks arerapidlycontained andhuman-to-human transmission isinterrupted, thereisa risk of sustained communitytransmission. •Atthe time of reporting,data from the WHO European RegionforDecember 2025had not yet been submitted; •InDecember2025,31countries acrossfiveWHO regions(European Region excluded)reporteda total of1040newconfirmedmpoxcases, includingsixdeaths (case fatality ratio [CFR] 0.6%).Ofthese cases,78%werereportedinthe African Region.Fourregionsobservedadeclineinconfirmedcases inDecember,compared to •Fifteencountries in Africareportedactive transmission of mpox in the last six weeks(7 December 2025–18January2026), with871confirmed cases, includingfivedeaths (CFR0.6%).Countries reporting the highest •Fourcountries,Czechia, Israel,Madagascarand Nepal, andtheterritoryofMayotte,France,have reported •Outside Africa,communitytransmission of clade Ib MPXVcontinuesto be reportedinFrance,Italyand Spain. •Madagascar is reporting an active mpox outbreak,which beganin early December2025among individualswithoutrecenttravel and quicklyexpandedacross the country, which currently is experiencingcommunity •WHO published ‘Analytical considerations for genomic surveillance of mpox virus’, outliningkey considerationsfor implementingMPXVgenomic surveillance,bringing together available evidence and expert input to support •Thereport also includes a phylogenetic analysis of MPXV sequences shared on open-source platforms,highlighting themaingeneticallydistinct strainsdetected ineachcountry since 2022. •WHO published the mpox global donor report on 21 January 2026, summarizing donor contributions andfunding allocationsduring the PHEIC period of the mpox response(August2024–September2025)across key •On 22 January 2026, the Africa Centres for Disease Control and Prevention lifted the declaration of a Public Thissituation report includesthe most relevantnewinformationonmpox outbreaks and response activities.Detailed Global monkeypox virus (MPXV) distribution Since thelast situation reportand as of 18January2026,fourcountries,Czechia, Israel, Madagascar and Nepal,and one territory, Mayotte(overseas Department of France),havereported mpox due to clade Ib MPXV for the firsttime(Figure 1).ForMadagascarand Czechia,this is thefirsttime they havereportedmpox cases.Detailed Figure 1.Geographic distribution of MPXVclades*reported to WHO, by country, 1 January 2022 to18 January *onecase of mpox due torecombinant clade Ib/IIbMPXVhas been reported in theUnited Kingdom, and currently, Reporting ofcommunity transmission of clade Ib MPXVoutside Central and East Africa(Figure 2)continuesin theWHO EuropeanRegion, inFrance,Italyand Spain,while investigations are ongoing to betterunderstand thesourceof infectionforthe case reported inCzechia.Since thelast editionof thisreport,twoadditionalcountries, FranceandMadagascar,havereportedcommunity transmission of clade IbMPXV.France has reported one case of mpox Global situation Global surveillancedataareupdatedmonthly;datapresented here areas of31December2025. As of the time of reporting, theWHOEuropean Region had not yet submitteddata forDecember 2025; InDecember2025,31 countriesreported1040confirmed cases(Figure 3), includingsixdeaths (case fatality ratio The countries with the highest number of confirmed cases in the last month are in the African Region (Figure3),which reported78% (809of1040) of confirmed casesin December 2025. Thedownward trend in confirmed mpox ThreeotherWHOregionsobserveda decreaseinconfirmedcasesinDecember2025compared toNovember2025:theSouth-East Asia Region (70%,7 vs 23 confirmed cases), theRegionof the Americas(64%,130vs363 TheEastern Mediterranean Regionreportedan increaseinconfirmedcasesfrom zero cases inNovember2025 Figure 4.Reportedconfirmed mpox cases,byWHO region,by month, 1January–31December2025 Situation in Africa This sectionreports on dataas of18 January2026. From 1 January2025to18 January2026,29countries in Africa reported44542confirmed mpox cases,including198deaths(CFR0.4%).Fifteencountrieson the continenthavereportedactive transmission of mpox in the lastsixweeks(Figure5), with871confirmed cases, includingfivedeaths (CFR 0.6%),during this period.Countriesreporting the highest number ofconfirmedcasesover the last six weeksare the Democratic Republic of the Congo, Overall,weeklyreportedconfirmed cases continue to declineonthe continent(Figure 6).Datafor the most recentweeks should be interpreted with caution, as reporting delays often lead to retrospective adjustments.Moreover,there is areductionin surveillance activities in several countries, whichmight hinderreportingofthereal numberof mpox cases.Overall,around100 new confirmed casesper weekhave been reported inrecentweeks.This Focus on selected countries Madagascar On 30 December 2025, the Ministry of Public HealthofMadagascardeclared