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第22版，《世界卫生组织卫生紧急情况方案流行病学公报》，世界卫生组织东南亚区域办事处，2025年11月5日。报告期：2025年10月20日至11月2日

2025-11-05世界卫生组织D***

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关键事件与更新

新发布：《国家卫生应急预警与响应框架》：该框架为各国协调应急响应提供指导，涵盖公共卫生职能、协调系统和应对各类健康紧急情况（包括灾害）的行动，适用于国家级和次国家级卫生应急协调机构及相关公共卫生专业人员和机构。
新发布：《蚊媒性登革热病例管理：初级卫生保健和家庭护理手册》：为一线卫生工作者提供登革热诊疗指南，包括疾病自然病程、诊断方法和基于证据的管理方案，强调早期识别、液体管理和及时转诊，并包含监测图表和疫情应对策略。

流感

东南亚区域情况：截至2025年11月4日，区域流感阳性样本占比12%，斯里兰卡和泰国阳性率呈上升趋势（分别为33%和38%）。
病毒亚型与谱系：2025年第42-44周，3314份样本中408份阳性，其中A(H3)亚型占主导（60%），B(Victoria)谱系占21%（印度占比最高），尼泊尔和斯里兰卡多数阳性样本未分亚型。不丹、马尔代夫和泰国以A(H3)为主。

COVID-19

东南亚区域情况：截至2025年11月2日，区域官方报告病例数据不完整，需参考WHO全球疫情 dashboard。
哨点监测趋势：8个国家（孟加拉国、不丹、印度、马尔代夫、尼泊尔、斯里兰卡、泰国和东帝汶）显示病例数和阳性率波动，具体数据以图3为准。

莫波克（mpox）

东南亚区域情况：截至2025年11月2日，区域累计1114例确诊病例（含14例死亡），其中19例为MPVX Ib谱系（印度10例，泰国9例）。
趋势图：以图4和图5展示病例数和谱系分布。

登革热

孟加拉国：2025年第44周新增6235例（同比增长11.5%），死亡20例（同比增长11.1%），全年累计病例72364例（同比增长112%），死亡286例（同比下降15%）。
印度喀拉拉邦：病例自第17周稳步上升，第27周后下降（见图7）。
印度卡纳塔克邦：2024年病例在第29周达峰值（超过4500例），2025年至今病例数较低。
马尔代夫：2025年9月报告254例（同比下降2.3%）。
尼泊尔：2025年9月报告1526例（同比增长33.5%），全年累计5323例（同比下降78%）。
斯里兰卡：2025年第43周新增654例（同比下降0.2%），全年累计41946例（同比下降1%）。
泰国：2025年9月报告4012例（同比下降53%），死亡1例（同比下降83%），全年累计47981例（同比下降43%）。

第22版，《世界卫生组织卫生紧急情况方案流行病学公报》，世界卫生组织东南亚区域办事处，2025年11月5日。报告期：2025年10月20日至11月2日

WHO Health Emergencies ProgrammeWHO Regional Office for South-East Asia22ndedition(2025),05 November2025Reportingperiod:20 Octto02 Nov2025 Thisepidemiological bulletin aims to providethe situation of key infectiousdiseases intheWHOSouth-East AsiaRegionto inform risk assessmentsand responses. The bulletin usesinformation from publicly availablesources and Key events and updates......................................................................................................................2New publication: National health emergency alert and response framework........................................................2New publication: Dengue case management for primary health care and home-based care: Booklet for healthprofessionals and health-care workers....................................................................................................................2Influenza............................................................................................................................................3Situation in the WHO South-East Asia Region..........................................................................................................3COVID-19............................................................................................................................................5Situation in the WHO South-East Asia Region..........................................................................................................5Mpox.................................................................................................................................................7Situation in the WHO South-East Asia Region..........................................................................................................7Dengue...............................................................................................................................................9Bangladesh...............................................................................................................................................................9India........................................................................................................................................................................10Maldives..................................................................................................................................................................11Nepal.......................................................................................................................................................................11Sri Lanka..................................................................................................................................................................12Thailand..................................................................................................................................................................13 Key eventsand updates New publication: National health emergency alert and response framework •This multi-hazard Health Emergency Alert and Response Frameworkprovides guidance for coordinating emergency response in countries, •It outlines the public health functions, coordination systems and actionsneeded for effective local, sub-national and national response to a broad •This guidance brings together existing initiatives within the broadercontext of evolving health emergency preparedness and response.•The audience for this framework is the primary national and sub-nationalauthorities with the designated responsibility for health emergencycoordination,and other relevant public health professionals and •While this document presents options for the possible sub-national andnational authorities that can develop and implement these capacities, it •The document is available athttps://www.who.int/publications/i/item/9789240113893. New publication: Dengue case management for primary health care and home-based care: Bookletfor health professionals and health-care workers •TheDengue Case Management for Primary Health Care and Home-BasedCare booklet, developed by the WHORegional Office forSouth-East Asia,is a comprehensive resource designed to strengthen frontline health-careresponse to dengue.•It outlines the natural course of dengue illness, diagnostic approaches,and evidence-based management protocols for both primary health-care settings and home-based care. Influenza Situation intheWHO South-East Asia Region Situation as of04 November2025 •Figure1showsthe influenza data from the WHO FluNet platform,accessedon04 November2025.•Duringweeks 42–44, there were 419influenzapositive samplesfrom 3314samplesin the SEARO region, withan overall positivityat12%. Influenza virus subtypes and lineages Week42-44 20252 •Table 1 presents the distribution of influenza virus subtypes and lineages in ten countries within the WHOSouth-East Asia Region for epidemiological weeks 42to 44of 2025, using data o

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