第13版，《世界卫生组织卫生紧急情况方案流行病学公报》，世界卫生组织东南亚区域办事处，2025年7月2日。报告期：2025年6月16日至6月29日

Key eventsand updatesBhutan: LeptospirosisSituation overview as of1July2025•On 1 July 2025,Ministry of Healthof Bhutan reportedacluster of Acute Respiratory Distress Syndrome (ARDS)amongpeople whoparticipated intheDe-suup(“Guardian of Peace”volunteers who conductcommunityservices anddisaster management)training conducted inDewathang,Samdrup Jongkhar District,SamdrupJongkhar District.Thediseasehasnowbeen confirmedasleptospirosis.•Out of 230 trainees, 143 exhibited symptoms and have been treated per clinical protocols.Of these, threepassed away.•All De-suup trainees are being monitored at a designated facility in Thimphu.•Diagnosisis based on laboratory results and epidemiological evidence;samples have been sent forreconfirmation to higher centers outside Bhutan.•Laboratory confirmation was done throughEnzyme-Linked Immunosorbent Assay(ELISA)and MicroscopicAgglutination Test (MAT) at the Royal Centre for Disease Control (RCDC),in collaboration withregional hospitals.•The Ministry of Health (MoH) acted early based on clinical signs and prior sporadic cases, guiding prompt casemanagement and diagnostic testing.Public health response•As part of thepublic health response, the Health Emergency Operations Center (HEOC) was activated tocoordinate field investigation and outbreak containment.•Those with mild to moderatesymptomsweretreated with appropriate antibiotics andisolated. Severely illpatients are managed at intensivecareunitsand isolation wards.•The surveillance team hascontactedall affected individuals and their families to ensure comprehensive follow-up and care.•Active case detection and surveillance efforts are ongoing.•Infection prevention and control measures have been reinforced nationwide.•All health facilities across Bhutan have been alerted to strengthen early detection and response.•Risk communication andcommunity engagement activities are ongoing.Thepublic, particularly in southernregions, is advised to avoid contact with floodwaters, maintain good hygiene, and seek medical attention ifsymptoms develop.1Ministry of Health ofBhutan.Press release–1 July2025.Available from:https://www.facebook.com/MoHBhutan/posts/pfbid07HuxAyZSyuNHesMLFfNFVL7xYyMcedcBZJiXgpS3gdfWeVkQ9qM4eKNyicfZDZZgl?rdid=Na16TF39QjzsCZIs# 1 2 COVID-19Situation in WHOSouth-East Asia RegionAs of29June2025•A surge of COVID-19 cases were observed in some countries in the Region, such asBangladesh,India,Myanmar, NepalandThailandin the recent weeks,startingaroundweek 17 to 21(Figure1).An increase inCOVID-19 deaths have also been recorded inBangladesh, India, Nepal and Thailand, following the surge of thecases.•In week26,(23to29June 2025),Bangladesh reported a total of115cases and6deaths2,India reported a totalof78cases and14deaths3,Thailand reported a total of18 961cases and25deaths4,Nepal reported a total of58cases5and one death while Myanmar reported a total of 16 cases6.•The Region has recorded a cumulative total of 61884209COVID-19 cases, including 809235deaths.•Globally, 778186599COVID-19 cases, including 7097227deaths have been cumulatively reported, as of8June20257.Please visit theWHO COVID-19 dashboardfor the global situation of COVID-19.Figure1.Weekly number of new COVID-19 casesand deathsreportedfrom selected countriessince week oneof 2025in the WHO South-East Asia Region(as ofweek 26).2Directorate General of Health Services (DGHS), Bangladesh. COVID-19 Dashboard [Internet]. Dhaka: Ministry of Health and FamilyWelfare; 2025 [cited 2025 Jun 17]. Available from:https://old.dghs.gov.bd/index.php/bd/component/content/article?layout=edit&id=56123Ministry of Health and Family Welfare, Government of India. COVID-19 India Dashboard [Internet]. New Delhi: MoHFW; 2025 [cited 2025Jun 17]. Available from:https://covid19dashboard.mohfw.gov.in/4Department of Disease Control, Ministry of Public Health, Thailand. COVID-19 Surveillance Dashboard [Internet]. Nonthaburi: DDC, MoPH;2025 [cited 2025 Jun 17]. Available from:https://dvis3.ddc.moph.go.th/t/DDC_CENTER_DOE/views/DDS2/death?%3Aembed=y&%3AisGuestRedirectFromVizportal=y5EpidemiologyandDiseaseControlDivisionNepal. Available from:Situatio...-Epidemiology and Disease Control Division, Nepal |Facebook6Ministry of Health, Republic of the Union of Myanmar. Ministry of Health official website [Internet]. Nay Pyi Taw: MoH; 2025[cited 2025Jun 17]. Available from:https://www.mohs.gov.mm/7World Health Organization (WHO). WHO Coronavirus (COVID-19) Dashboard [Internet]. Geneva: WHO; 2025 [cited 2025June 8]. Availablefrom:https://data.who.int/dashboards/covid19/cases 3 4•Based on data fromtheintegrated influenza-SARS-CoV-2 sentinel system,Figure 2 summarizes weekly trendsofeight countries—Bangladesh, Bhutan, India, Maldives, Nepal, Sri Lanka, Thailand, and Timor-Leste—highlighting number of positive COVID-19 cases, the percentage positivity and the number of specimens tested.oBangladesh,India, Maldives andThailand,Bangladeshhave shown an increase inpositivity and confirmedcasesstartingaround week 1