第17版，《世界卫生组织卫生紧急情况方案流行病学公报》，世界卫生组织东南亚区域办事处，2025年8月27日。报告期：2025年8月11日至8月24日

WHO Regional Office for South-East Asia17thedition(2025),27August2025Reportingperiod:11Augto24Aug2025 Thisepidemiological bulletin aims to providethe situation of key infectiousdiseases intheWHOSouth-East AsiaRegionto inform risk assessmentsand responses. The bulletin usesinformation from publicly availablesources andwill be published every two weeks.Forfeedback or suggestions, please writetoseoutbreak@who.int. Key events and updates......................................................................................................................2Nepal: Cholera outbreak...........................................................................................................................................2New publication: WHO Malaria Control in Emergencies: Field Manual (2025)....................................................3Influenza............................................................................................................................................4Situation in theWHO South-East Asia Region..........................................................................................................4COVID-19............................................................................................................................................6Situation in theWHO South-East Asia Region..........................................................................................................6SARS-CoV-2 variants in the South-East Asia Region.................................................................................................8Mpox.................................................................................................................................................9Situation in the WHO South-East Asia Region..........................................................................................................9Dengue.............................................................................................................................................11Situation in theWHO South-East Asia Region........................................................................................................11Bangladesh.............................................................................................................................................................12India........................................................................................................................................................................13Maldives..................................................................................................................................................................14Nepal.......................................................................................................................................................................14Sri Lanka..................................................................................................................................................................15Thailand..................................................................................................................................................................16Annex...............................................................................................................................................17WHO resources on mpox........................................................................................................................................17 Key eventsand updates Nepal:Choleraoutbreak Situationoverviewas of26August 2025 •On 25 August 2025, the Nepal Ministry of Health and Populationpublished a press releasee regarding anoutbreak ofacute watery diarrhea (AWD) inBirgunj Metropolitan City,Parsa district,Madheshprovinceinsouthern Nepal1. •According to the Public Health Emergency Operations Center of Madhesh Province2:oOn 22 August, health facilities in Birgunj Metropolitan City reported a sudden increase of AWD cases.oAs of 18:00 on26 August,a total of 422 cases ofAWDwere reported between 9 and 26 August.oOfthe 422 cases,-20 were confirmedas Vibrio Choleraeby culture, 114 tested positive using cholera rapid diagnostic tests,and 288 remain suspected.-age group15 to 24 yearsweremost affected(112 cases,27%), while22 cases (5%)were under age 5.-67% ofcases areconcentrated in four wards, namelythe ward 11, 12, 13 and 14.-atotal of 199casesremain under treatment (31 in Intensive Care Unit/High Dependency Unit (ICU/HDU)and 168 in general wards), while 223 patients have been discharged.-nofatalitieshave been reported. Response234 •District disaster management committee meeting was held in presence of Provincial Minister ofthe Ministry ofHealth and Population (MoHP), and action points on risk communication, clinical management,human resourcemanagement, logistic and supply management, information management, WASH interventions, and outbreakinvestigations were discussed. •Another meeting