世界卫生组织晚期艾滋病毒疾病管理指南

WHO guidelines onthe management ofadvanced HIV disease WHO guidelines on the management of advanced HIV disease ISBN 978-92-4-011816-4 (electronic version)ISBN 978-92-4-011817-1 (print version) © World Health Organization 2025 Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO licence (CC BY-NC-SA 3.0 IGO;https://creativecommons.org/licenses/by-nc-sa/3.0/igo). Under the terms of this licence, you may copy, redistribute and adapt the work for non-commercial purposes,provided the work is appropriately cited, as indicated below. In any use of this work, there should be nosuggestion that WHO endorses any specific organization, products or services. The use of the WHO logo isnot permitted. If you adapt the work, then you must license your work under the same or equivalent CreativeCommons licence. If you create a translation of this work, you should add the following disclaimer along withthe suggested citation: “This translation was not created by the World Health Organization (WHO). WHO isnot responsible for the content or accuracy of this translation. The original English edition shall be thebinding and authentic edition”. Any mediation relating to disputes arising under the licence shall be conducted in accordance with themediation rules of the World Intellectual Property Organization (http://www.wipo.int/amc/en/mediation/rules/). Suggested citation.WHO guidelines on the management of advanced HIV disease. Geneva: World HealthOrganization; 2025. Licence:CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data.CIP data are available athttps://iris.who.int/. Sales, rights and licensing.To purchase WHO publications, seehttps://www.who.int/publications/book-orders.To submit requests for commercial use and queries on rights and licensing, seehttps://www.who.int/copyright. Third-party materials.If you wish to reuse material from this work that is attributed to a third party, such astables, figures or images, it is your responsibility to determine whether permission is needed for that reuse and toobtain permission from the copyright holder. The risk of claims resulting from infringement of any third-party-owned component in the work rests solely with the user. General disclaimers.The designations employed and the presentation of the material in this publication donot imply the expression of any opinion whatsoever on the part of WHO concerning the legal status of anycountry, territory, city or area or of its authorities, or concerning the delimitation of its frontiers orboundaries. Dotted and dashed lines on maps represent approximate border lines for which there may notyet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they areendorsed or recommended by WHO in preference to others of a similar nature that are not mentioned. Errorsand omissions excepted, the names of proprietary products are distinguished by initial capital letters. All reasonable precautions have been taken by WHO to verify the information contained in this publication.However, the published material is being distributed without warranty of any kind, either expressed orimplied. The responsibility for the interpretation and use of the material lies with the reader. In no event shallWHO be liable for damages arising from its use. Design and layout:blossom.it Contents Acknowledgements.............................................................................................................................................ivAbbreviations.......................................................................................................................................................viDefinitions of key terms....................................................................................................................................viiExecutive summary...........................................................................................................................................viiiSummary of recommendations.......................................................................................................................viiiDefinition of advanced HIV disease..................................................................................................................xiiObjectives..............................................................................................................................................................1Target audience....................................................................................................................................................2Guiding principles.................................................................................................................................................2Burden of advanced HIV disease...................................................................................................