金斯瑞生物科技2024中期报告
23572244454647495153 (i)(ii)CDMO(iii)(iv) 22 1007,284 CDMO cilta-celMMTCAR-T 1531 97927 ESG 183171712–1716 4th Floor, Harbour Place103 South Church Street, George TownP.O. Box 10240, Grand Cayman KY1-1002Cayman Islands 860 Centennial AvenuePiscatawayNJ 08854U.S. www.genscript.comwww.probiocdmo.comwww.legendbiotech.comwww.bestzyme.com 24840 — 1548 Harneys Services (Cayman) Limited4th Floor, Harbour Place103 South Church StreetGeorge TownP.O. Box 10240, Grand Cayman KY1-1002Cayman Islands •561.4391.343.5%281.1281.80.2%280.3109.5156.0% •307.0175.075.4%133.5134.70.9%175.341.4323.4% •215.6245.8 69.0162.029.233.613.1%98.3195.7 (2)(i)(ii)(iii)(iv)(v)(vi)(vii)(viii) 561.4391.343.5%307.0175.075.4%175.193.6 (i)(ii)(iii)(iv)38.8%6.6%4.6%49.9% 1. 222.4203.09.6%119.9110.58.5%47.838.623.8% (i)(ii)(iii) 2. 40.465.137.9%5.919.569.7%30.0%14.7%18.97.8 (i)(ii)(i)(ii)(i)(ii) 3. 26.118.243.4%11.07.252.8%39.4%42.2%2.30.4 (i)(ii) 4. 280.5109.7155.7%CARVYKTIcilta-cel 119.4205.9196.3168.8cilta-cel52.449.138.041.6 561.4391.343.5%(i)CDMO(ii)CARVYKTI(iii) 175.075.4%307.073.3% 81.419.5%97.3cilta-cel21.9% 106.512.9%120.25.7% 207.314.0%236.4cilta-cel12.7% Probio Technology LimitedProbio CaymanProbio Cayman300,000,000Probio Cayman AProbio A189,393,939ProbioCaymanProbioProbioCaymanProbio Cayman150.0Probio CaymanProbio125.0Probio Cayman Probio CaymanProbio Cayman319,998,370ProbioCayman CProbioC224.0Probio C Probio AProbio CProbio Probio AProbio C463.7113.5 Probio CaymanProbio Cayman57,314,000Probio Cayman BProbio B37.3ProbioBProbioB ProbioB 37,609,0705.3250.035.210.4168%AA A Probio B1.640.11.1A37.31.2 1.110.0CDMO 215.6245.869.0 399.3149.633.1 231.0373.9 112,00033.7100.3 2.5%5.9%13 (i)(ii) (a) 14.075.0% (b) *AB 14.075.0% 1.31.7 GS47.06.62.4%GS174.124.42.38%2.6% 96.113.5(LPR) 250.0250.041.612(SOFR)LIBOR/SOFR122.5% 35.34.996.113.5 361,0007.71.6 233.132.7BProbio Cayman 4.24.845.2%39.6% 68,054 244,121 CGTsgRNAGMP FDAECCARVYKTI(MM)CARVYKTI IT 60.0 170.8 500.4 500.7 (i) (ii) (iii) cilta-celCARVYKTI(i)FDACARVYKTI(ii)LEGENDBIOTECH USA INC.(iii)CARVYKTI343(iv)CARVYKTI®(v)CARVYKTICARTITUDE-4 10020100,000 CDMOCDMO2000LGMPCAR-TCDMOCDMO CARVYKTIIITIIT 7,284 270.348.1% Probio CaymanProbio CaymanProbio XVXV78352C3 (1)Genscript CorporationGS Corp9.60%GS CorpGS Corp21,852,800GSCorp218,306,000GSCorp18,306,000GS Corp20,700,935GS CorpII (2)GS Corp20.93%GS Corp0.53% (3)160,0001,643,320280,706 (4)GS Corp4.15%GS CorpGS Corp (5)GS CorpGSCorpGS Corp799,999,123GSCorp1,118,72011,041,707GSCorp (6)120,00038,150,000168,630 (7)1,622,388GS CorpGS Corp8.06% (8)120,000634,0001,242,711 (9)GS Corp22.76%GS CorpGS Corp (10)LiliHuangLiliHuang638,000 (11)44,86058,0004,478 (12)10,451270,0004,478 (13)10,451270,0004,008270,00010,451 (14)16,95716,957 (15)3,906,33765,6832,000,0001,091,513 (16)3,585,1245,000,000880,993 XV(i)352(ii) XV23336 (1)GSCorp224A4L44443B9.60%20.93%0.53%4.06%0.53%4.60%22.76%0.25%3.99%3.72%3.72%2.45%4.76%3.77%4.15%8.06%1.05%1.07% (2)GS Corp20.93%GS CorpGS Corp4.06%0.53%4.60% (3)GS Corp8.06%GS Corp (4)Descendants’ Separate Trust FBO AADescendants’ Separate Trust FBO LL17,000,000GS Corp (5)Lili Huang638,000Lili HuangLili Huang (6)GNS Holdings LimitedHillhouse Investment Management V, Ltd.Hillhouse FundV, L.P.GNS Holdings Limited XV23336 ProbioProbio 1,219,801A 444,59811,450,84370,335BB20%BB 10%1% (i)120.1%(ii)1% 82,090,141152,308,888 17212,768,65121,276,865 11,825,1062,116,588,2400.5587% 17.14Probio CaymanProbio17 (1)22 17 (1)10.65(2)22(3)60,000(4)270,000(5)60,000 (i)(ii)(iii)17 (i)(ii) 1,219,801 23 (1)(2)10.60(3)44,860(4)10,451(5)44,860(6)16,957(7)(8)(9) (i)(ii)17 (i)(ii)(iii) (i)(ii) 444,59811,380,508 23 (1)(2)11.78(3)(4)(5) 1818 25% C1 (i)(ii)(iii) 13.51B(1) ESGESG ESG 360,000480,000100,000 13.51(2)(a)(e)(g)13.51B(1) 2024 ᆿ≮ᴹ䀾ᑡӁएᡶ俏⑥券冐⏂㤧ⲽ䚉 㲕འਚжᓝ⁉ Tel䴱䂧: +852 2846 9888Fax۩ⵕ: +852 2868 4432ey.com Ernst & Young27/F, One Taikoo Place979 King’s RoadQuarry Bay, Hong Kong 4594343434 2410 34 2024 2024 2024 2024 1. 34— 2. 20202022 161177 16——16 12 2. 77 3. (a)(b)(c)(d)CAR-T(e) 3. 3. 4. (a) 4. (a) 5. 6. 7. 21%21%0.75%9.99%2.5%11.5% 12.5%12.5%25%25%25%25% 5%5%17%17% 200,000200,00019%19%25.8%25.8% 7. 25% 15%15% 15%15% 15%25% 8. 9. 2,116,588,2402,106,881,564 64,914,63477,308,534 10. 32,707,00033,370,000Probio Cayman B 37,480,00016.5% 11. 250 (a) 4,949,0005,036,00019 11. (b) (i) (ii) 13. 18,870,00019,433,000 14. 14. 16. 35,731,00065,336,000 17. 17. 3,000,0003,839,000 19. (a)250,000,00041,600,000LIBORSOFR12(SOFR)LIBOR/SOFR122.5% (b)4,949,0005,036,000(LPR)LPR4.20%4.20% 20. (a)Probio AProbio C ProbioCaymanA300,000,000ProbioAProbio AProbio ProbioCaymanC319,998,370ProbioC30,000,00042,857,000C Probio AProbio C (1) Probio CaymanProbio CProbio A8%Probio Probio CProbio A (2) Probio AProbio CAAProbio A0.50CCProbio C0.70AC Probio CaymanProbio AProbio CProbio Cayman
