FORM 10-K/A(Amendment No. 1) (Mark One)☒ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2025 or ☐TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from _______ to_______ Commission File Number:001-00100 THERAPEUTICSMD, INC.(Exact name of Registrant as specified in its Charter) 561-961-1900(Registrant’s telephone number, including area code) Securities registered pursuant to Section 12(b) of the Act: The Nasdaq Stock Market LLC Securities registered pursuant to Section 12(g) of the Act: None Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes☐No☒ Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. Yes☐No☒ Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the SecuritiesExchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports),and (2) has been subject to such filing requirements for the past 90 days. Yes☒No☐ Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submittedpursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that theregistrant was required to submit such files). Yes☒No☐ Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smallerreporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smallerreporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act: Large Accelerated Filer☐Non-accelerated filer☒Emerging growth company☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period forcomplying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.☐ Indicate by check mark whether the registrant has filed a report on and attestation to its management’s assessment of the effectivenessof its internal control over financial reporting under Section 404(b) of the Sarbanes-Oxley Act (15 U.S.C. 7262(b)) by the registeredpublic accounting firm that prepared or issued its audit report.☐ If securities are registered pursuant to Section 12(b) of the Act, indicate by check mark whether the financial statements of theregistrant included in the filing reflect the correction of an error to previously issued financial statements.☐ Indicate by check mark whether any of those error corrections are restatements that required a recovery analysis of incentive-basedcompensation received by any of the registrant’s executive officers during the relevant recovery period pursuant to §240.10D-1(b).☐ Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes☐No☒ As of June 30, 2025, the registrant’s most recently completed second fiscal quarter, the aggregate market value of the voting and non-voting common equity held by non-affiliates computed by reference to the market price at which the common equity was last sold was$9,036,147. As of March 30, 2026 there were outstanding 11,574,362 shares of the registrant’s common stock, par value $0.001 per share. Documents Incorporated by Reference None. EXPLANATORY NOTE This Amendment on Form 10-K/A (“Amendment No. 1”) to our Annual Report on Form 10-K for the fiscal year ended December 31,2025, as filed with U.S. Securities and Exchange Commission on March 30, 2026, is being filed in order to correct printer errors in thefollowing sections: ●A printer error in the section entitled, “Item 12. Security ownership of certain beneficial owners and management and relatedstockholder matters” in Footnote 4.●Printer errors in the section entitled, “Item 15. Exhibits and financial statement schedules” to update and correct hyperlinks tocertain exhibits and to add Footnote 34.●A printer error in the “Index to Financial Statements” to update and correct the Report of Independent Registered PublicAccounting Firm and to delete a placeholder report. Except as described above, there are no other changes contained in this Amendment No. 1, and we have not updated disclosuresincluded therein to reflect any subsequent events. TABLE OF CONTENTS PagePart IItem 1.Business1Item 1A.Risk factors11Item 1B.Unresolved staff comments37Item 1C.Cybersecurity37Item 2.Properties38Item 3.Legal proceedings39Item 4.Mine safety disclosures39Part IIItem 5.Market for registrant’s common equity, related stockholder matters, and issuer purchases of equitysecurities40Item 6.Reserved40Item 7.Management’s