艾美疫苗2023年度报告

股份代號：（於中華人民共和國註冊成立的股份有限公司） 248344463649095969899101195196 Ker Wei PEI Ker Wei PEI Ker Wei PEI ACGHKACG Ker Wei PEI 97927 H • 1617 1820 25 2920 10564412 126 91A25 06660 www.aimbio.com 3485 •S SS P3434 821312,000+ 20236.3627.2%53.6% 14215III13233 21TOP10 21 13 2024mRNA mRNAmRNAmRNA RSVmRNA 2024-2026 ໨ԫึ˴ࢩ੔Ⴇ 20233312MSCIAIPOA+H 2023 CEO周延2024415 mRNAmRNAmRNA312,0008VeroVeroAC YW135(MPSV4)21 202314215III5III13(PCV13)III23(PPSV23)IIIEV71-CA16mRNAmRNA202437 +202312311,187.520226.1% 142191413(PCV13)III23(PPSV23)III20239IIIAC YW135(MCV4)IIIAC YW135(MPSV4)IVEV71-CA16Delta-OmicronBA.5 mRNAIIIIII20(PCV20)b(Hib)MDCK (CHO)20325 203090%65%202220224(ACIP)1959 10μg/0.5ml20μg/0.5ml10μg20μg16160.5ml20μg0.5ml100% Vero Vero2007920086GMP 2007Vero16100%mRNA (HAV)HAV115320Eu/0.5ml15640Eu/1.0ml20215920219202262022GMP AC Y W135(MPSV4) 20203MPSV4MPSV4AC YW135201810MPSV4201812GMPMPSV4MPSV4MPSV4(MCV4)II Vero Vero2007920082GMP2018VeroVero20226GMP2022VeroVero 820041020051GMP20202GMP20206GMP (1)13III(2)23III2024(3)20(4)24 PCV13671202010PCV1320212I20243PCV13III2024 PCV132023PCV13IIIPCV13III3,78071 136620302001325.9%80% 131.813 GMP1323III (1)III2024(2)2024(3)mRNAmRNA Vero mRNAmRNAmRNAmRNA mRNA mRNAmRNAmRNA mRNA RSVmRNAmRNAGSKRSV20235202324.6GSK202343.7mRNA2024mRNA mRNA AC YW135(MCV4) MCV4ACYW135320232I20233I120III EV71-CA16 71(EV71)A16(CA16)CA16CA16EV71-CA16EV71-CA16EV71CA16 mRNAAImRNAAI (i)(ii)mRNAmRNAmRNA mRNAPCV13PCV20 PPSV23 MCV4RSV202030EV71-CA16EV71Sabin IPV3030 20231231GMP20231231 20231231 20212023 2019121 mRNAmRNAmRNAmRNAmRNAmRNADNAmRNA2024221mRNA230mRNA127mRNAmRNA PCV13PPSV232018PCV1334.6%65.6%2022PCV1372.6%88.3%PPSV23PCV132022107.522.7%2025240PCV13PCV20PCV24PCV 20195,88020217,85033.6%2030220203035.0%mRNA2030mRNA21.2% 20243RSVRSVmRNARSV2022mRNA-13456083.7% mRNA0.1%2030200 2015202261719.4%203012.3%2,203mRNA (2024-2026)13 GMP1323III 2024 20231,187.520221,264.176.66.1%2030 2023286.52022236.45021.2% 202390120221,027.7126.612.3% 202375.9%202281.3%5.4% 202351.7202249.62.14.1%2023 2023636.42022500.3136.127.2% 20234942022493.20.80.2% 2023254.32022450.8196.543.6% 20234.2202227.22384.6% 2023123161,091,000 202312311,512.2211.420221516 mRNAmRNAmRNA 2023mRNA20231231 mRNAmRNA2023mRNAmRNAmRNAmRNA2023mRNAmRNAmRNA 202343.8202225.718.170.6% 2023320.42022203.5116.957.4%20231231 20231,950.22022230.61,719.6745.6%20231,723.72023 20231231736.420221231797.861.47.7% 202312312,482.92,601.9119.020221231298.9417.9 20231231509.920221231504.75.21%20231231 202312311,005.1202212311,052.647.54.5%2023 2023301.620232022856.655564.8%2023 202312311,795.6202212311,398.7396.928.4%20232023123126 2023123146.2%2022123123.9%22.3% 20231231(1)20231231259.420221231286.5(2)20231231592022123161.1(3) 20231231 20231231 1231 202312311,624202212311,5762023362.42022608.0 20231231 91.612023102320231231 (1)mRNAmRNAmRNA(2)202312mRNA(3)20236PCV13PCV20PPSV23(4)20231 2023382023428202320232023H2023817 (a)35(b)242,212,5191.00 20233820234112023830202342812 202320231231 58201552021692020122021520215 102012520122021630201352018811513020111020135 999.9966.44%(i)73.02%(ii)76%(iii)75%(iv)70%(v)51%76%99.99% 20141220155W.P.W.P.20221 57202122021692024229201612202062021220213 20151120168201410201511 2014320089 6120178202169202121820233292020122021320216 20174202122007120173199882007960121126111992919998 1986720065W.P. 602015520216920151220161220161220209 20125201352017599.99% 20139 55201352021692024229 2010620201299.99% 201220226 6020206202169 20232201722013120171200232013119842200211982919841 200672015W.P.19978 5120179202169 20172600873200942017220083200941998120083 20231231XV 20091020171201610201610 Ker Wei PEI672020919 Pei1998720225W.P.1986119926W.P.1992719987199872003620037201362013720176Pei199719931994 Pei201260576200760151200860672Pei2015720191212082006520125600019201562022122012220199Pei20184 Pei197961981519865 612021528 20197201012201322018120196 2019420226175320178202372318 198271985719901219931019985 602021528 201432011320143200182011230067619853200172004 1981202112311997 201511SARS 522021218 2017920212201132017101998220112 1993620091020214 5520212 2012520191220106201112200612201062003720061260051120106201112300290201453000242022520000989 1999620026200272005 62201512 25200891992820088 719926 2013620206 2018919 52201510 200612201112 1993620205W.P.20061220096 412011112015112022320215 2019122021620142201912007820115 20185W.P. 20213 20195202132019820213201952019820139201842010520132 20096201712 4620181020223 2011220181020081220112 20215SPACE 5920224 2020420138202046001611985720138 1985719921994199412 2023 H20221062022923(www.hkexnews.hk)(www.aimbio.com) 1 4783339 392430 C2 20231231 195 13 1231530% 20231231530% 2022106H16.169,714,000H20221028H16.161,348,600H91.61 2023123129 31 2023123120221231 •••••••• Ker Wei PEI 3443 13.51(2)13.51B(1) 13.51(2)13.51B 2020111,979202011202412319,540,0000.5 2023123