艾美疫苗2023年中期报告

（於中華人民共和國註冊成立的股份有限公司） 股份代號： 中期報告2023 2 4 20 32 33 34 36 39 Ker Wei PEI Ker Wei PEI Ker Wei PEI ACGHKACG Ker Wei PEI 97927 H 1617 1820 25 2920 16218 126 91A25 06660 www.aimbio.com 3485 mRNA31VeroVeroACYW135(MPSV4) +2023630540.520228.6% 1423914Delta-OmicronBA.5mRNAIIIEV71-CA1613(PCV13)III23(PPSV23)IIIVero20221020237IIIAC YW135(MCV4)20232I2024III (CHO)20325 HBsAg10μgHBsAg20μgHBsAg 10μgHBsAg20μgHBsAg16202363033.3%100% Vero Vero2007920086GMP 202363060.0%2007Vero16100% (HAV)HAV115320Eu/0.5ml15640Eu/1.0ml20215920219202262022GMP2023 AC Y W135(MPSV4) 20203MPSV4MPSV4AC YW135201810MPSV4201812GMPMPSV4MPSV4MPSV4202363014.7 2007920082GMP201820226GMP2022 820041020051GMP20202GMP20206GMP (1)IIIIIIIII Delta-Omicron BA.5 mRNA Delta-OmicronBA.5 mRNAmRNADeltaOmicronBA.5mRNADelta-OmicronBA.5 mRNA 2023325IIIIIIIII 13(PCV13) PCV13202010PCV1320212I2022PCV13IIIIIIPCV1320242024 PCV132022PCV13IIIIPCV13III3,78071 EV71-CA16 EV71-CA1671(EV71)A16(CA16)EV71-CA16EV71CA16202272022102023 AC YW135(MCV4) MCV4ACYW135320232I20233I1202024III •Vero20221020237III •23(PPSV23)20238III mRNA (i)(ii)mRNAmRNAmRNAmRNA mRNA10PCV13PCV20 PPSV23 MCV4DTP 2023630GMP2023630 2023630mRNA2022 202120229DTP-Hib202211 2019121 20221302022510 2015251202176120302,15720213,03620304,314mRNA 2025 Delta-OmicronBA.5 mRNAIIImRNAmRNAEV71-CA1613(PCV13)III23(PPSV23)IIIVero20221020238IIIAC YW135(MCV4)20232I2024III2023 2023540.52022591.651.18.6% 2023107.82022109.92.11.9%2023 2023432.62022481.649.010.2% 202380.1%202281.4%1.3% 202321.0202220.80.20.9%2023 2023398.52022194.0204.5105.4%mRNA 2023224.92022233.08.13.5% 2023115.72022185.669.937.7% 202319.1202210.28.987.2% 202352.42022183.2130.871.4%25%15% 20233.720226.62.944.7% 2023257.4202250.9308.3605.3%2023 2023630754.920221231797.842.95.4% 20236302,548.32,269.7 2023630547.620221231504.742.98.5% 20236301,052.4202212311,052.60.20.1% 2023111.020232022454.9343.975.6%2023 20236301,687.5202212311,398.7288.820.6%2023 202363030.3%2022123123.9%6.4% 2023630(i)2023630277.420221231286.5(ii)202363060.12022123161.1(iii) 2023630 2023630 20236301,57220226301,5282023175.22022231.9 2023630 91.612023630 (1)20233mRNACOVID-19SARS-CoV-2(2)20236PCV13PCV20PPSV23(3)20231 2023382023428202320232023H (a)35(b)242,212,5191.00 2023382023411 2023630 20237428,697,000202363030,889,00028,697,0002,192,000 2023630 2023630XVXV78352 (1)(2)20236301,211,062,599718,888,888492,173,711H (3)200,000,00099.99%200,000,00010,135,23523,254,765H (4)5,000,00098%20,000,0005,150,000H5,160,000H (5)25,000,00025,000,000H 2023630XV(i)XV7878(ii)352(iii) 2023630336XV235% (1)(2)20236301,211,062,599718,888,888492,173,711H(3)(4)76.75%42.68%44,300,00055,700,000H(5)70.00%54,051,428H(6)49%51%61.25%40,000,000H(7)51%49%90%40,000,000H(8)0396883.20%17,990,000H19,240,000H(9)60087325,000,000 2023630XV23336 18 20201130202221620201130 (a) (b) (c)12,106,6661%1%2023630H (d)6.98 (e)2020113084 (f) 2023118448011,806,6662023112023630202363011,556,66620236300.95% (1)(i)20221212023113030%(ii) 20231212024113030%(iii) 20241212027113040% (2) 20236300.95% 20201231186,958,000 12.4312.7413.482.606.98(%)43.64%-45.78%(%)–(%)3.02%-3.08%37 21,855,000202229,287,000 2023630 20217500.02023630(a)2021(b)2023630 13.2013.2113.22 2023630 C.2.1 2023630 2023630 13.51(2)13.51B(1) 23182023720 13.51(2)13.51B Ker Wei PEIKer WeiPEIKer Wei PEI2023630 40322022 33512023630343434 2410 34 2023829 2023630 2023630 2023630 2023630 2023630 1. 20111192020918202092316218 2022106 2.1 20236303420221231 2.2 20221231 1281212 2.2 (a)12202311 (b)8202311 (c)1212 2023630 2.2 (d)1220231120231231 3. 4. 4. 5. 6. 7. 25% 20221012202363015% 20211119202363015% 20211210202363015% 20211210202363015% 2022525[2022]191915%1915% 2023630 8. 20236302022630 9. 1,211,062,59920226301,199,999,999 20232022630 10. 202363020221231277,417,000286,515,000 20236302022123184,022,00086,307,000 202363072,123,0002022630424,999,000 202363091,000202263050,00080,000202263050,000 11. 2023630 11. 12. 13. 14. 15. (a) 15. (b) (i)20236305,315,00020226305,135,000202363013,706,0002022123118,275,00015,384,0002022123120,275,000 (ii)2023630168,0002022630168,000 (iii)2023630138,0002022630120,000 (iv)2023630612,0002022630 15. (i)2015100%20237428,697,000202363030,889,00028,697,0002,192,000 (d) 2023630 16. 202363020221231 17. 15(c) 18. 2023829 %