艾美疫苗2025年中期报告

（於中華人民共和國註冊成立的股份有限公司）股份代號：06660 目 錄 2 5 30 41 42 43 45 46 48 62 202541720254132025417 2025417Ker Wei PEI20254 17 2025413 Ker Wei PEI(2025413 2025417202541720254172025413Ker Wei PEI20254 1720254172025417 2025520 Ker Wei PEI20254132025417 2025417202541720254132025417 153232033207 10564412 ACGHKACG2025613ACGHKACG2025613 20256132025613 2T626 97927 331919182025110 H 1617 25 399 06660 www.aimbio.com mRNA312,00068VeroACYW135(MPSV4) 12202324171EV71-CA16ImRNAmRNA 2025413(PCV13)23(PPSV23)IIIIII2025III2026132313 mRNA5312,000+100% 2025 MPSV4 VeroACYW135(MPSV4) +2025630514.720244.2% 1220152313(PCV13)23(PPSV23)IIIIII2025IIIACYW135(MCV4)IIEV71-CA16IMDCKb(Hib)(CDE)mRNA RSVmRNA20(PCV20) (CHO)20325 203090%65%202220224(ACIP)1959 10μg/0.5ml20μg/0.5ml10μg20μg16160.5ml20μg0.5ml100% Vero Vero2007920086GMP 2007Vero18100%mRNA (HAV)HAV115320Eu/0.5ml15640Eu/1.0ml20215920219202262022GMP ACYW135(MPSV4) 20203MPSV4MPSV4ACY W135201810MPSV4201812GMPMPSV4MPSV4MPSV4(MCV4)II (1)13(PCV13)(2)23III(3)20(4)24 PCV13671PCV13 PCV132024PCV13III71IIIPCV13 136620302001325.9%80% 13 GMP1323III (1)(2)III Vero III mRNAmRNAmRNA mRNA mRNAmRNA mRNA RSVmRNAmRNAGSKRSV20235202324.6GSK202343.7mRNAmRNA RSVmRNA(CDE)(FDA)mRNA mRNA ACYW135(MCV4) (MPSV)122MCV4MCV4MCV2MCV4MCV4ACYW1353II EV71-CA16 71(EV71)A16(CA16)CA16CA16EV71-CA16EV71-CA16EV71CA16 mRNAAImRNAAI (i)(ii)mRNA 2025630GMP2025630 201912 1 2024()1017.79.8%2025 20242.546,00020257 281520252020202410HBsAg5.86%HBV7,50027 2002HBV12024–2030(2025–2030) mRNAmRNAmRNAmRNAmRNAmRNADNAmRNAFDAmRNAmRNA PCV13PPSV232018PCV1334.6%65.6%2022PCV1372.6%88.3%PPSV23PCV132022107.522.7%2025240PCV13PCV20 PCV24PCV 20195,88020217,85033.6%2030220203035.0%mRNA2030mRNA21.2% 20256RSVRSVRSV2024531mRNA RSVmRNAmRNA2030RSV154 mRNA20302390.2%2030200 2015202261719.4%203012.3%2,203 2025MPSV4 13PCV13(MOU)(MENA) 2024–202613 VeroACYW135(MPSV4) GMP1323III 20251323mRNA 2025514.72024537.222.54.2% 2025173.42024148.924.516.5%2025 2025341.22024388.347.112.1%2025 202566.3%202472.3%6.0% 202510.5202413.42.921.4%2025 2025107.02024170.163.137.1%20242025 2025232.12024232.20.10.1% 2025126.22024124.22.01.6%2025 20257.620243.93.7 202528.5202430.01.55.1%2025 202515.6202414.01.611.4% 2025136.02024145.39.36.4%2025 20256 30401.920241231594.9193.032.4% 20256 302,213.93,026.2812.320241231702.9109.4132320256 30128,000,000566,000,000 2025630433.920241231462.628.76.2% 20256301,165.0202412311,123.841.23.7% 2025102.520252024119.517.014.2%13 20256301,778.5202412311,841.362.83.4%2025 202563050.2%2024123151.0%0.8%2025 2025630(1)2025630240.720241231249.7(2)202563069.92024123171.1(3) 2025630 2025630 20256301,49320246301,5572025166.92024180.4 2025630 H 202522820252 285.0115,500,000Factorial Master Fund77,655,00071,638,000202536 77.775.04.822025228H 2026630 202563091.61 2025630 2025630 2025630XVXV78352 (1)(2)20256301,226,562,599718,888,888507,673,711H (32025630200,000,0001,326,800H99.99%200,000,000 (4)5,000,00098%20,000,0005,150,000H5,160,000H 2025630XV(i)XV7878(ii)352(iii) 2025630336XV235% (1)(2)20256301,226,562,599718,888,888507,673,711H(3)(4)76.75%42.68%44,300,00053,236,200H(5)70.00%54,051,428H(6)49%51%61.25%40,000,000H(7)60087325,000,000H 2025630XV23336 18 20201130202221620201130 (a) (b) (c)12,106,6661%1%20246 30H (d)6.98 (e)2020113084 (f) 202511784743,351,000202511202563020256300 20201231186,958,000 12.4312.7413.482.606.98(%)43.64%-45.78%(%)–(%)3.02%-3.08%37 2024630 20256302025630 20256302011802022(a)2021(b)2024(a)(b)20232025630 13.2013.2113.22 2025630 C1C.2.1 20254 2520247120254252025428 202552020255202025520 2025630 2025630 13.51(2)13.51B(1) 13.51(2)13.51 B(1) (1)2025413(2)2025413(3)2025417 13.51(2)13.51B 2025630Ker Wei PEIKer Wei PEI2025630 D2 D240D2322024 21920256 30343434 2410 34 2025827 2025630 2025630 2025630 2025630 2025630 2025630 1. 201111920209 18202092310564412 2022106 2.1 20256303420241231 20256 30812,288,0001220256 30128,000,000566,000,000122025630 2025630 2.2 20241231 21 21 3. 4. 2025630 5. 6. 2025630 7. 25% 20221012202563015%2025630202563015% 20241224202563015% 2024126202563015% 2024126202563015% 20231212202563015% 2025630 7. 20225 1720211115% 8. 20256302024630 9. 1,221,081,93620246301,211,062,599 2025630 9. 20256302024630 10. 202563020241231240,724,000249,748,000 202563020241231283,288,000290,790,000 202563055,276,00020246 3066,188,000 2025630572,00020246 30123,000160,000202463047,000 11. 2025630 11. 12. 13. 2025365.01Factorial Master Fund15,500,00015,500,00053,631,000 2025630 14. 15. (a) 15. (i)20256305,375,00020246305,505,00020256 305,212,000202412 315,212,000202412 315,212,000 (ii)2025630168,0002024630168,000 (iii)2025630138,0002024630132,000 2025630 15. (i)2015100%20237 428,697,00020256 3032,948,00028,697,0004,251,000 (d) 2025630 16. 202563020241231 2025630 17. 18. 2025827