绿竹生物-B2023年中期报告

股份代號: 2480（於中華人民共和國註冊成立的股份有限公司） 24561624252627282943 •8835 3212101-2105 183401 (FCG HKFCG(PE)) (FCG HKFCG(PE)) 112-14 7 3 H 1617 13 2480 www. luzhubiotech.com 3 202358 3485 2001 2023630LZ901 2023630LZ901 H202358H241.6 Fabite®Fabite®TFabite®2-8˚C Fabite® LZ901 LZ901VZVVZVFcAPCLZ901VZVLZ901I 20235LZ901IILZ901GMCGMTLZ901GMCGMTAE0-7IIIIIIAE23.74%6.02%1.00%AE29.0%23.0%13.0%LZ901IIIVAEAEIIIII2023LZ901III2024LZ901BLA2025LZ901III50LZ901III4020227FDALZ901IND2023220237 LZ901I2024LZ901I2024LZ901II20252025III2027 K3 K3TNF-αHumira®20189IK3201912I2024K3III2024III20242025BLAK32025BLA2025 K193 K193BBCD19CD193CD3K193CD19/CD3K193Fabite®K193K193BK193201912K193I2024I2024K193II2027K193II K333K1932 (2)K3II 202363029 GMP202363028GMP •LZ901K3K193•K333K1932••• 20232022630 20226306.416.1%20236305.33.620236301.6 20226302.990.3%20236300.320221B+20226302.52023630 20226308.694.7%202363016.8(i)5.9(ii)2.3 2022630551.5202363020226 202263044.67.5%202363041.29.42.1 202263055.239.9%202363033.226.3 20226300.312.5%20236300.4 202263012.5111.5%202363026.5 2022630652.187.8%202363079.4 2023630 25%20222023630 202263088.039.9%202363052.92023630202263022.0 202263069.0297.22023630366.2 202363010.02.35% 2023630 2023630 2023630 20236307.9%2022123112.4% 2023630 2022123113.5202363025.7 2023630 2023630 2023630 20236302022630 H202358241.62023552023528 2023630 2026 20236301292023630 2023630XVXV78352 (i) (1)(2)(3)2023630(4)2023630(i)34.00%46.00%(ii)60.00%80.00%(i)(ii)(iii)(iv)(5)202363049.51%(6)40.67%(i)(ii)(7)H (ii) 2023630 2023630XVXV78352 2023630XV23336 H (2)202363040.67%(i)(ii) (3)2023630(i)34.00%46.00%(ii)60.00%80.00%(i)(ii)(iii)(iv) (4)2023630(i)(ii)(iii)60193957.11% (5)2023630(i)(ii)40.00%40.00%20.00%20236307,776,0502,224,694(i)(ii) (6)H 2023630XV23336 20211215B.3. C.2.1C.2.1(i)(ii) 2023630 2023630 2023630 2023630 3.10(2)3.21 202363020236302410 202363013.51B(1) 202363018 2023630 25422023630343434 24102410 34 20226302410 •2023821 20236 30 20236 30 20236 30 20236 30 20236 30 1. 202358 2023630 2. 34 3. 202363020221231 202311 17202062021121781212 4. 202363020226302023630 5. 6. 20236 30 7. 8. 2023630242,129,00020221231170,512,000202363017,876,0002022123119,922,0002023630224,253,00020221231150,590,000 9. 10. 2022630 20236 30 11. 20226301819(b) 12. 46,622,0002022630 13. 42,846,000202263040,426,00077,277,0002022630 20236 30 16. 202333010,000,00020226302.35% 17. (i)(ii) 18. i.20226C92,481,0002,034,582,000 ii.20235832.8010,386,000110,386,000289,797,000340,660,800300,183,00010,386,00041,255,000 20236 30 19. (a)2022 20222022420222022 2022 (b) 20218301.00LZ901II405% LZ901II20224202263020225278,694,5131.008,695,00090,907,000 19. (c)2022 20211 20224 202248,110,13212022(i)7,450,0007,450,00012.545.097.19(ii)1,942,320660,13212.948,110,1323,875,00020224,235,132 20225 20236 30 19. (c)2022 2022 2022C (d) 2022618350,00010,000,000118,9523,398,68011.00 20221231 19. (d) C 2023630 20236 30 20. 9 21. a. 2023630 b. 16202363010,000,000 22. 1.00 2016525 GMP H1.00 K3TNFα H202358 202358H LZ901 2015121(i)60.00%(ii)10.00%10.00%20.00%