脊髓灰质炎过渡进展：监测和评估报告（2025年第三季度）

countries1and in countries in the watch list2towards the goals and strategic outcomes of the Polio Transition Strategic Framework.The report provides updated data for the indicators on immunization, released in July 2025, mid-year data for the indicators on surveillance and outbreak response, andanupdate on milestone indicators. Highlights: As emphasized in the 8th Report of the Transition Independent Monitoring Board, as of Q3 2025, the context for poliotransition remains immensely challenging. In 2024, despite epidemiological progress, twelve polio transition prioritycountries reported atotal of 22 cVDPV outbreaks. Furthermore, many priority countries continue to experienceoutbreaks of other diseases, includingmeasles outbreaks,despitesignificantefforts to mitigate risks and raise immunitythrough the ‘Big Catch-up' programme. Immunization coverage remains sub-optimal in most priority countries, withonly one country reaching the 90% IPV and DTP3 coverage benchmark during 2024. Fragile governance and insecurity At the same time, there are emerging signs of progress. Surveillance quality and sensitivity continue to show a mixedpicture across priority countries. Whilst the number of countries meeting the threshold for non-polio AFP rates declinedfrom 18 to 13 between December 2024 and June 2025, and ES surveillance sensitivity also dropped, the timeliness ofsample results improved, as did the rate of discarded non-measles non-rubella cases annually. Operationally, strongerintegration between polio and essentialimmunization activities has begun through the first joint Gavi-GPEI boardmeeting in June 2025. There have also been concerted efforts to bolster country laboratory capacity to enable countriesto have greater ownership over sample testing. Country transition planning has become more tailored and, in some countries, has begun to be embedded more systematically as a critical step following the closure of a polio outbreak. At 1In 2024-25, thelistof21prioritycountriescomprisesAngola,Burkina Faso,Cameroon,Central African Republic,Chad,Democratic Republic oftheCongo,Ethiopia, Guinea, Madagascar, Mali, Mozambique, Niger,NigeriaandSouthSudanintheAfricanRegion;Afghanistan,Pakistan,Somalia, Sudan, Syrian Arab Republic and Yemen in the Eastern Mediterranean Region; and Myanmar in the South-East Asia Region.2The ‘watch list’ comprises Kenya*in the African Region; Iraq and Libya in the Eastern Mediterranean Region; Bangladesh, India, Indonesia and 1.Progress Towards Impact Goals Afghanistan and Pakistan continue to be polio endemic for wild polio virus.In 2024, 12 polio transition priority countries reported a total of 22 cVDPVoutbreaks. Moreover, Indonesia, a watchlist country, also experienced anoutbreak during the same period. IPV1 coverage remains sub-optional(less than 90%) in all priority countries, except one, indicating that there isa considerable readiness barrier for successful bOPV cessation post- GOAL 1: All countries remain poliofree Fourteencountriesremain belowthe benchmark for DTP3 coverage at thesub-national level, indicating significant challengesin achievingbaselineimmunity againstvaccinepreventable diseases. Further, WUENIC data asof June 2025 demonstrates the third dose of polio vaccine (POL3)coverage globally in 2024 was 84%, still below pre-pandemic coverage of86% in both 2018 and 2019. Whilst the ‘Big Catch Up’ has enabledintegrated delivery of an additional 227M total doses of polio vaccine GOAL 2: Minimize the burden of andeliminatevaccine-preventable Despite progress toward strengthening preparedness, detection, andtimely response to public health emergencies, there are still challenges oftimeliness and sensitivity of surveillance systems and timely response tooutbreaks. Most of the priority countries reported significantly lowerscores than the regional average on the International Health Regulations(IHR)core capacity indicators for laboratory capacity and healthemergency management.Repeated outbreaks of polio underscore health GOAL3:Rapidlydetectandcontroldiseaseoutbreaks 2 Progress Towards the Strategic Outcomes The indicators for strategic outcomes measure health systems performance and resilience related to the essentialfunctions: immunization surveillance, health emergency preparedness andresponse, and poliovirus containment. SO 1:National immunization programmes systematically reach and immunize Prioritycountries: Most of the priority countriesreportedIPV1 and DPT3 coverage gradually increasing or stable over the period 2023-24. However,ten priority countries reportedcoverages of both IPV1 and DPT3 below 70% in 2024: Afghanistan, Angola, Central AfricanRepublic, Chad,Democratic Republic of Congo, Guinea, Madagascar, Nigeria, Sudan and Yemen. Equity remains also a challenge Watchlistcountries: Among watchlist countries, five countriesare ontrack for IPV1 and DTP3 coverage,two countries have IPV1 coverages lowerthan 90%: Indonesia and Kenya, 81% and88% respectively,