Incannex Healthcare Inc美股招股说明书(2025-07-24版)

Amended and Restated Sales Agreement (the “Sales Agreement”), dated May 27, 2025, by and among the Company, A.G.P./Alliance the information herein amends or supersedes the information contained in the Prior Prospectuses. This Prospectus Supplement is notcomplete without, and may only be delivered or utilized in connection with, the Prior Prospectuses and any future amendments orsupplements thereto.We are filing this Prospectus Supplement to amend the Prior Prospectuses to update the amount of shares we are eligible tosell pursuant to such Prospectus. We are increasing the amount of shares of Common Stock we may offer and sell under the SalesAgreement by an aggregate offering price of up to $100,000,000 from time to time through the Sales Agents, which is in addition tothe shares of Common Stock having an aggregate gross sales price of approximately $63,469,250 that were sold pursuant to the PriorProspectuses to date. Investing in our securities involves a high degree of risk. See “Risk Factors” beginning on page S-6 of the ProspectusSupplement dated April 7, 2025 and the risk factors incorporated by reference into this Prospectus Supplement and the PriorProspectuses, as they may be amended, updated or modified periodically in our reports filed with the Securities and ExchangeCommission. these securities or passed upon the adequacy or accuracy of this Prospectus Supplement or the accompanying prospectus. Anyrepresentation to the contrary is a criminal offense. A.G.P.Curvature The date of this Prospectus Supplement is July 24, 2025