兆科眼科-B：截至2024 年12 月31日止年度全年业绩公告及有关认购理财产品的须予披露交易

Zhaoke Ophthalmology Limited 6622 20241231 2024123120231231 NVK002AwAMDTAB014BRIMOCHOL™ PFCEDZKY001 •NVK0022024NVK0022025120248NVK002IIIChina CHAMP202410 •A20248IIIIII •wAMDTAB014III20249TAB014III20251TAB014 •202469.3202318.8268.6%32.61,200202010234.7BRIMOCHOL™ PF •20249®20241220253 •20241Kwangdong Pharmaceutical Co., Ltd.KDPBRIMOCHOL™ PFKDP20243PharmaniagaTRB®EyeGiene®20251AFTBRIMOCHOL™ PF wAMDDMECED NVK002Vyluma NVK002 •24•NVK002IIICHAMPChina CHAMP •CHAMP16526ChinaCHAMP18777 •CHAMPIII2024III20251NVK0020.01% •20248China CHAMPIII202410NVK002NVK002•NVK002(0.01%) A A • •AAAA•IIICOSMO41644A •20247AIIIIII20239•COSMO2025 TAB014wAMD TAB014wAMDVEGFwAMD •TAB014IIITAB014Lucentis®52 •60488 •20239TAB014III20249•20251•TAB014 BRIMOCHOL™ PFCARBACHOL™ PFTenpoint BRIMOCHOL™ PFCARBACHOL™ PF •BRIMOCHOL™ PFα2CARBACHOL™ PF••BRIMOCHOL™ PFCARBACHOL™ PFTenpointTenpointTenpointIII •20241BRIMOCHOL™ PFCARBACHOL™ PFIII•III2025324II•20251TenpointBRIO-IIBRIO-IIIIIBRIMOCHOL™ PF82025 ZKY001 ZKY0014 •ZKY001 •ZKY001IICEDTPRKNK TPRKCEDZKY001ZKY001III ®20232 •2024920®® •20241292025318 • 18A.08(3) 100 20241231203.72023333.138.8%NVK002TAB014IIIBRIMOCHOL™ PFCARBACHOL™ PFIII ®®2024920241220253 202311 2024301,200530.4 15,400 2024129KDPBRIMOCHOL™PFBRIMOCHOL™ PFKDPKDP VisusTenpoint20242TenpointBRIMOCHOL™ PFCARBACHOL™ PF 20247NVK002Vyluma 20243®PharmaniagaEyeGiene®TRB 2025113AFTBRIMOCHOL™ PFAFTBRIMOCHOL™ PF 20246 FDAEMA ®® 2024NVK002NVK002 (ESG) 20249202410 ESG20244ESG 2025 20251NVK0022026 AIII20252025A 20251TAB014III2025TAB014 BRIMOCHOL™ PFCARBACHOL™ PFII2025III AIIIFDA2025FDA 1224 20241231237.520231231385.0202433.5NVK002TAB014III 2024123169.32023123118.8 202010233.5®30.420234.72024 KDP1.220235.62024123114.9 202412312023123182.087.3 2024123118.3202312313.52024 (i)CRO(ii)(iii)(iv)(v)(vi) 2024123120231231333.1129.438.8%203.7NVK002TAB014IIIBRIMOCHOL™ PFCARBACHOL™ PFIII (1) 2024123170.82023123184.413.6 (1) 202412312023123151.963.52024 20241231202312317.99.52024 2023123120241231 2017120204 25% 10% 20241231237.520231231385.0 (1) 202412311,614.91,121.0356.351.569.516.620241231313.084.74.5212.611.2 CRO30 20241231212.6 20241231356.32023265.7 (1)(2) (1)(2)100%(3)202320241231 20241231 2024123195.42023123158.337.1BRIMOCHOL™ PFCARBACHOL™ PFIIIAIII 20241015Barclays Bank PLC202010,000,000 (1)Barclays Bank PLCBarclaysBank PLC (2)20 (3)20202532010,000,000 5%25%14.0725% 20241231 20241231 2024123129420241231 51.79733.05318.03712.66321.410.33813.0294100.0 20241231115.520231231126.813.6 202412312024123120241231 20242023 369,32418,750(17,527)(4,503) (227,991)(376,567) 5(a)(9,502)(7,921) 5(237,493)(384,488) 6–(550) (237,493)(385,038) (0.43)(0.71) (0.43)(0.71) 80,58761,107 (156,906)(323,931) 30,38935,569 1,900,0772,048,318 –*–*1,900,0772,048,318 1,900,0772,048,318 1. 201712020204292219613Vistra (Cayman) Limited, GrandPavilion, Hibiscus Way, 802 West Bay Road, George Town, Grand Cayman 2. (a) 20241231 2(b) (b) 3. (a) 20242023 15 30,4434,7362,151–2,0038,41433,523– (b) 4. (i)(ii) (i)(ii) 5. (a) 8,0946,1651,4081,756 (b) 32,56931,6338,1218,411 2,2402,1509981,107 6. 20242023 7. (a) 237,493,0002023385,038,000546,139,1722023543,922,707 20242023 (b) 202420231231 動 部 分 18571,38112–6672378–*36671,6626377– 9. 20242023 113366 10. 202412312023 C.2.1 C.2.1 C1 C3 2021429123,567,5001,932.320241231 20241231 20241231 20241231 20241231 20241231 2025516 202551320255162025512183171712–1716 (www.hkexnews.hk)(zkoph.com)20241231 FDA AAZKY001 AT DME KDPKwangdong Pharmaceutical Co., Ltd.009290 GEM C3 NK 21 PharmaniagaPharmaniaga Logistics Sdn. Bhd.Pharmaniaga BerhadPHARMA 20241231 0.00000025 TenpointTenpoint Therapeutics Limited VEGF VisusVisus Therapeutics, Inc.202412TenpointTenpoint 2025324