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Joint FAO/WHO Meeting onPesticide Residues EVALUATIONS2023 PartII – Toxicological Pesticide residuesin food – 2023 Toxicological evaluations Sponsored jointly by FAO and WHO Joint Meeting of theFAO Panel of Experts on Pesticide Residuesin Food and the Environmentand theWHO Core Assessment Group on Pesticide Residues Washington D.C., United States of America, 19–28 September 2023 The summaries and evaluations contained in this book are, in most cases, based onunpublished proprietary data submitted for the purpose of the JMPR assessment.A registration authority should not grant a registration on the basis of an evaluationunless it has first received authorization for such use from the owner who submittedthe data for JMPR review or has received the data on which the summaries arebased, either from the owner of the data or from a second party that has obtainedpermission from the owner of the data for this purpose. Pesticide residues in food 2023: Joint FAO/WHO meeting on pesticide residues. Evaluation Part II –Toxicological. ISBN (WHO) 978-92-4-009930-2 (electronic version)ISBN (WHO) 978-92-4-009931-9 (print version)ISBN (FAO) 978-92-5-139154-9 © World Health Organization and Food and Agriculture Organization of the United Nations, 2024 Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO licence (CC BY-NC-SA 3.0 IGO;https://creativecommons.org/licenses/by-nc-sa/3.0/igo/). Under the terms of this licence, you may copy, redistribute and adapt the work for non-commercialpurposes, provided the work is appropriately cited, as indicated below. In any use of this work, thereshould be no suggestion that the World Health Organization (WHO) or the Food and AgricultureOrganization of the United Nations (FAO) endorse any specific organization, products or services. Theuse of the WHO or FAO logo is not permitted. If you adapt the work, then you must license your workunder the same or equivalent Creative Commons licence. If you create a translation of this work, youshould add the following disclaimer along with the suggested citation: “This translation was not createdby the World Health Organization (WHO) or the Food and Agriculture Organization of the United Nations(FAO). WHO and FAO are not responsible for the content or accuracy of this translation. The originalEnglish edition shall be the binding and authentic edition”. Any mediation relating to disputes arising under the licence shall be conducted in accordance with themediation rules of the World Intellectual Property Organizationhttp://www.wipo.int/amc/en/mediation/rules. Suggested citation.Pesticide residues in food 2023: Joint FAO/WHO meeting on pesticide residues.Evaluation Part II–Toxicological. Geneva:World Health Organization and Food and AgricultureOrganization of the United Nations; 2024. Licence:CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data.CIP data are available athttps://iris.who.int/. Sales, rights and licensing.To purchase WHO publications, see:https://apps.who.int/publications/book-orders.To submit requests for commercial use and queries on rights and licensing, see:http://www.who.int/about/policies/publishing/copyright. Third-party materials.If you wish to reuse material from this work that is attributed to a third party,such as tables, figures or images, it is your responsibility to determine whether permission is neededfor that reuse and to obtain permission from the copyright holder. The risk of claims resulting frominfringement of any third-party-owned component in the work rests solely with the user. The designations employed and the presentation of the material in this publication do not imply theexpression of any opinion whatsoever on the part of WHO or FAO concerning the legal or developmentstatus of any country, territory, city or area or of its authorities, or concerning the delimitation of itsfrontiers or boundaries. Dotted lines on maps represent approximate border lines for which there maynot yet be full agreement. The mention of specific companies or of certain manufacturers’ products, whether or not these havebeen patented, does not imply that they are endorsed or recommended by WHO or FAO in preferenceto others of a similar nature that are not mentioned. Errors and omissions excepted, the names ofproprietary products are distinguished by initial capital letters. All reasonable precautions have been taken by WHO and FAO to verify the information contained in thispublication. However, the published material is being distributed without warranty of any kind, eitherexpressed or implied.The responsibility for the interpretation and use of the material lies with thereader. In no event shall WHO and FAO be liable for damages arising from its use. Contents Abbreviations and acronyms..................................................................................ivIntroduction.......................................................................