TRELYSA LONG|JUNE 2026 Manufacturing start-ups, particularly in critical national economic power industries, are essentialto the nation’s economic and security strength. Yet, U.S. manufacturing start-ups have declinedover the last three decades. KEY TAKEAWAYS U.S. manufacturing start-ups are declining at a time when all other start-ups are growing.From 1989 to 2023, U.S. manufacturing start-ups declined 58 percent from an index of100 to 42.5. All other start-ups grew from 100 to 104.6. Most of the decline occurred prior to 2009 and appears related to the significant drop inU.S. manufacturing competitiveness. Manufacturing start-ups have declined faster than total manufacturing firms. From 1989to 2023, manufacturing start-ups declined from an index of 100 to 42.5, while totalmanufacturing firms declined from 100 to 74.8. The average manufacturing start-up is now smaller. Manufacturing start-ups’ averagenumber of employees fell from 9.2 in 1989 to 7.7 in 2023. Dual-use, enabling, and nonstrategic industries had very similar rates of decline, rangingfrom 57 percent to 60 percent. In contrast, defense industries had a much smaller rateat 45 percent. The is likely due to facing much less overseas competition. Manufacturing start-ups have not declined because of growing industry concentration, as82.3 percent of manufacturing industries saw a decline or slight increase (< 5 percent) inconcentration. To avoid losing more manufacturing strength to China in economic power industries, theUnited States should set a national goal of at least doubling the annual number ofmanufacturing start-ups in its economy. CONTENTS Key Takeaways ................................................................................................................. 1Introduction ..................................................................................................................... 2Manufacturing Start-Up Firms in Decline............................................................................. 4Fewer Young Manufacturing Firms ...................................................................................... 7Start-Ups’ Average Employees .......................................................................................... 10Manufacturing Start-Ups in Defense, Dual-Use, Enabling, and Nonstrategic Subsectors.......... 11A Likely Cause Is The Growing U.S. Trade Deficit ............................................................... 12Industry Concentration Was Not the Cause for Manufacturing Start-Up Decline...................... 13Policy Recommendations................................................................................................. 15Conclusion ..................................................................................................................... 15Methodolgy .................................................................................................................... 16Endnotes ....................................................................................................................... 17 INTRODUCTION Start-ups play a crucial role in the evolution of economies.1No matter how healthy incumbentcompanies are, some will eventually shrink or even die. Moreover, start-ups are critical ways ofinjecting necessary innovation and enabling creative destruction. National economic power industries, most of which are in manufacturing, are a cornerstone ofnational competitiveness and geopolitical independence. Yet, over the past three decades, theUnited States has seen a steep decline in manufacturing start-ups—a trend that bodes ill for thefuture of U.S. manufacturing. At one level, the decline should not be a surprise, given that real valued manufacturing outputhas declined as a share of gross domestic product (GDP).2But the decline in start-ups was 10percent more than the decline in manufacturing output. And the average employment size ofmanufacturing start-ups has also declined. Despite proclamations from policymakers and industry advocates—including former EnergySecretary Jennifer Granholm, who claimed that U.S. industrial policy “has revived Americanmanufacturing, created jobs, and made our country more secure”—the underlying data tells adifferent story.3The decline in start-ups in what the Information Technology and InnovationFoundation (ITIF) defines as dual-use sectors and enabling sectors is particularly troubling asChina continues to expand production in these critical industries. (Seebox 1.) To ensure that the United States slows or, ideally, reverses its relative decline in nationaleconomic power industries, policymakers need to promote a more robust manufacturing start-upecosystem and policy environment. Box 1: Defining National Economic Power Industries The conventional view is that defense industries are the only industries that matter to nationalpower. But that is now vastly too limiting. As Corelli Barnett, wrote, “For munitions productionfor