快速科学建议关于乘客的管理：在安第斯病毒在邮轮船MV Hondius爆发背景下

Rapid Scientific Advice on the management ofpassengers In the context of the Andes virus outbreak on the cruise ship MV Hondius 9 May 2026 Key messages As of9May 2026,a total ofeightcasesofAndes virus infection, including three deaths and one critically ill patient,linked to the M/V Hondius cruise ship have been reported. •ECDC has classified all people on board the ship and for the purpose of disembarkation and repatriation tobe high-risk contacts.•Monitoring/quarantineup to six weeks (42 days); Day 0 = 6 May 2026.High-risk contacts:self-quarantine, daily symptom monitoring, test if symptomatic.Low-risk contacts:passive monitoring; isolate and test if symptoms develop.•Flights:trace contacts for probable/confirmed cases only (same row ±2 rows on long flights).•IPC:masking, one to two metres distancing, PPE for healthcare/cleaning•Strongrisk communicationand misinformation management. This document provides advice for public health professionals in the EU/EEA managing individuals potentiallyexposed to ANDV, including on: •Defining contact classification criteria based on level of exposure, including close and prolonged contactwith symptomatic people;•The identification, management and monitoring of contacts, including advice on testing;•Appropriate infection prevention and control (IPC) measures for managing repatriated passengers andcrew, suspected and confirmed cases and their contacts in healthcare and community settings; and•Risk communication, community engagement and the management of misinformation. ECDC rapid scientific advice disclosure statement: ECDC issues rapid scientific advice to meet an emergent orurgent public health need or to quickly reply to external requests. To accommodate the accelerated timeline, theprocess and methods used for the development of rapid scientific advice may be modified from those ofstandard assessments and recommendations. Potential limitations are described. Background In early May 2026, hantavirus infections were identified among passengers and crew on a cruise ship travelling in theSouth Atlantic. As of 8 May 2026, a total of eight cases, including three deaths and one critically ill patient, linked to thecruise ship have been reported. Of these, six have been laboratory-confirmed as Andes virus (ANDV) infection. Theoutbreak occurred on the cruise ship MV Hondius, which departed from Argentina on 1 April 2026 and travelled throughthe South Atlantic towards Cabo Verde. A total of 149 passengers and crew from 23 nationalities were on board and afurther 30 passengers disembarked on 24 April in St. Helena. Stockholm, 9 May 2026 Hantaviruses are a group of zoonotic viruses transmitted to humans primarily through contact with contaminated rodentexcreta, usually by inhalation. Andes virus is of particular concern because very limited human-to-human transmissionhas been reported, primarily after close and prolonged contact with symptomatic individuals. The incubation periodranges from one to six weeks. Infection can initially present with fever, respiratory and gastrointestinal symptoms andcan progress rapidly to severe disease or death. Given the very limited but documented potential for human-to-human transmission associated with ANDV, aprecautionary approach to contact identification, listing, tracing and follow-up is recommended. Each country can adapt their response to the local epidemiological situation, the latest available science, and availableresources. Methods The information provided in this report is based on: •Data reported to ECDC through the Early Warning and Response System (EWRS) and the European surveillanceportal for infectious diseases (EpiPulse) and communication with EU/EEA Member States and partners;•Available epidemiological information related to the outbreak, including reports from national authorities;•Evidence from peer-reviewed publications on hantavirus infection, including ANDV transmission, clinical presentationand infection prevention control and measures; and•Consultation with experts from the World Health Organization (WHO) Regional Office for Europe and WHOHeadquarters, and the EU Reference Laboratory for Public Health on Emerging, Rodent-borne, and Zoonotic ViralPathogens (EURL-PH-ERZV). Limitations A complete epidemiological, microbiological and environmental investigation is still ongoing, with limited informationcurrently available on the travel history of cases, risk exposures prior to boarding the ship, contacts among passengersand crew on board. Environmental sampling and extensive search for rodent reservoirs on the ship will be undertaken inSpain. In addition, there is limited evidence in literature on ANDV for human-to-human transmission. Acknowledgments ECDC would like to acknowledge the WHO Regional Office for Europe and WHO Headquarters, and theEU ReferenceLaboratory for Public Health on Emerging, Rodent-borne, and Zoonotic Viral Pathogens (EURL-PH-ERZV) for thecollaboration in developing the advice pr