AxoGen Inc美股招股说明书(2026-01-21版)

Our common stock is listed for trading on the Nasdaq Capital Market under the symbol “AXGN.” The last reported saleprice of our common stock on the Nasdaq Capital Market on January 20, 2026 was $31.87 per share. Investing in our common stock involves a high degree of risk. See the section titled “Risk Factors” beginning on page S-10of this prospectus supplement, in the accompanying prospectus and in the documents incorporated by reference intothis prospectus supplement and the accompanying prospectus to read about factors you should consider before deciding to (1)See “Underwriting” beginning on pageS-29for additional information regarding underwriter compensation. We have granted the underwriters an option for a period of 30 days to purchase up to an additional $12.75 million ofshares of our common stock at the public offering price set forth above, less underwriting discounts and commissions. The underwriters expect to deliver the shares against payment in New York, New York on or about January Neither the Securities and Exchange Commission nor any state securities commission has approved ordisapproved of these securities or determined if this prospectus supplement or the accompanying prospectus istruthful or complete. Any representation to the contrary is a criminal offense. Prospectus SupplementPageProspectus Supplement Summary.....................................................................................................................S-3Risk Factors......................................................................................................................................................S-10Cautionary Note Regarding Forward-Looking Statements..............................................................................S-17Use of Proceeds.................................................................................................................................................S-18Dividend Policy................................................................................................................................................S-19Capitalization....................................................................................................................................................S-20Dilution.............................................................................................................................................................S-22Material U.S. Federal Income Tax Consequences for Non-U.S. Holders of Our Common Stock...................S-24Underwriting.....................................................................................................................................................S-29Legal Matters....................................................................................................................................................S-37Experts..............................................................................................................................................................S-37Where You Can Find Additional Information..................................................................................................S-37Incorporation by Reference...............................................................................................................................S-38 ProspectusPageAbout this Prospectus.......................................................................................................................................1Cautionary Note Regarding Forward-Looking Statements..............................................................................2The Company....................................................................................................................................................3Risk Factors......................................................................................................................................................5Use of Proceeds.................................................................................................................................................6Description of Capital Stock.............................................................................................................................7Description of Debt Securities..........................................................................................................................10Description of Warrants....................................................................................................................................18Global Securities...............................................................................................................................................20Plan of Distribution...........................................................................................................................................23Legal Matters..............................................................