新加坡：抗菌药物耐药性国家战略行动计划

TheNationalStrategicActionPlanonAntimicrobialResistance(AMR)wasdeveloped by theOne Health AMR Workgroup (OH AMRWG)and isjointly •Communicable DiseasesAgency (CDA)•National Environment Agency (NEA)•National Parks Board (NParks) Forenquiries,pleasecontactthe Secretariat at:Antimicrobial Resistance CoordinatingOffice, CDASingapore National Strategic Action Plan on Antimicrobial Resistance, Singapore (version 2.0) ONE HEALTH AGENCIES: TABLEOFCONTENTS FOREWORD................................................................................................................................2LISTOFABBREVIATIONS........................................................................................................3VISION AND MISSION...............................................................................................................5INTRODUCTION.........................................................................................................................6OVERVIEW OF AMR IN SINGAPORE...................................................................................7DEVELOPMENT OF NSAPv2..................................................................................................10STRUCTURE OF NSAPv2.......................................................................................................12CORE STRATEGIES.................................................................................................................13GOALS & TARGETS................................................................................................................14CORESTRATEGY01. COMMUNICATION & EDUCATION..............................................17CORE STRATEGY 02. SURVEILLANCE & RISK ASSESSMENT.......................................22CORESTRATEGY03.RESEARCH & EVIDENCE................................................................28 FOREWORD TheOne Health Agencies–comprising theCommunicable Diseases Agency,National Environment Agency, National Parks Board, PUB Singapore’s NationalWater Agency, and Singapore Food Agency–play a key role in shaping Singapore’s AMR, in particular, has been a growing concern globally as it threatens the ability to treatinfectious diseases. On the human health front, it poses risks to medical advances andpatient outcomes, contributing to increased mortality and greater healthcarecosts.AMR To combat these threats, Singapore’s first National Strategic Action Plan (NSAP) on AMRwas launched in 2017. It has since delivered several meaningful outcomes. Notably, itserved to formalise and structure efforts across the human, animal and environmentsectors. We have embarked on public education campaigns on correct antibiotic use,expanded AMR surveillance programmes and technical capabilities across all sectors, Notwithstanding these successes, AMR is a long-term threat that requires sustainedaction. As the AMR situation continues to evolve globally and new challenges occur,Singapore must remain vigilant and adapt our national AMR strategies accordingly. The One Health agencies are therefore pleased to share Singapore’s second NSAP onAMR (NSAPv2), which represents the nation’s renewed commitment to combat AMR,harnessingour strengths in One Health collaboration,research expertise,good The success of the NSAPv2 hinges on our collective effort. We are grateful to allstakeholderswho have contributed to shaping this enhanced plan.We invite allstakeholders to continue playing their part in tackling AMR. Together, all of us can LISTOFABBREVIATIONS AAHSAquatic Animal Health ServicesACEAgency for Care EffectivenessACGACE Clinical GuidelinesAHC2ASEANHealth Cluster 2ALDASEAN Leaders DeclarationAMRAntimicrobialResistanceAMRCOAntimicrobial Resistance Coordinating OfficeAMRWGAntimicrobial Resistance WorkgroupAMUAntimicrobial UtilisationANIMUSEANImal antiMicrobial USEARBAntimicrobialresistant bacteriaARGAntimicrobialresistance genesASEANAssociation of Southeast Asian NationsASF-AMR ASEAN Strategic Framework to Combat AMR through One HealthApproachASWGFiASEAN Sectoral Working Group for FisheriesASWGLASEAN Sectoral Working Group for LivestockASPAntimicrobialStewardshipProgrammeATLASSAssessment Tool for Laboratories and AMR Surveillance SystemsCDACommunicable DiseasesAgency IHR JEEInternational Health Regulations Joint External EvaluationInFARMInternational FAO Antimicrobial Resistance MonitoringIPCInfection Prevention and ControlMDRMultidrug resistant/resistanceM&EMonitoring and EvaluationMOEMinistry of EducationMOHMinistryofHealthMRSAMethicillin-resistantStaphylococcus aureusNARCCNationalAntimicrobialResistanceControlCommitteeNAREPNationalAntimicrobialResistanceExpertPanelNASEPNationalAntimicrobialStewardshipExpertPanelNAISNational Adult Immunisation ScheduleNCISNational Childhood Immunisation ScheduleNEANationalEnvironmentAgencyNIPCNationalInfectionPreventionandControlCommitteeNSAPNationalStrategic Action PlanOHOne HealthOHARPOne Health AMR Research ProgrammeOHCCOne Health Coordinatin