制药工艺与装备4：制药工程与设备&从实验室到生产
AI智能总结
082025ڼ08 ᄱ߾ᅝᇑጎԢ!ᄱײ߾ᇑยԢ!ٗํᄓڟิׂ ٗํᄓ ڟิׂᅜ ඇ૾ ཉ Ԩཱི ࣅ ظ ႎዘ ໒ ᄱ ႜ ᄽิ ༀ 螨暵⚥㕂ⵖ蚋猰䪮剣ꣳⰖ䚪絑椚 %S"OESFBT3JTDI ࣄ֧༬՚48 ݣ㢜㵹͇❴ݯ⩌ϔ䃫ิ䄰ⵁܳᲽ ᅝ߾रຍᇑײࡗ82㢜ጒ㞧ឭᱜݣݯݣᬍ㣹ᣏ⾣ ዊଉ੦118 ㉏侙冮㗪࣌᫆㢜⩌ϔ䓴⼸͚ᱯ䉕ᣔݣ⮱≮⼸хࡃゃ⪒ᣏᲽ ాۆᔅਙᒙ˜ؐǐځךћᘎɮ Ì᠏ިǻȡਙ 䔂渿⚥㕂ⵖ蚋⚌ 1IBSNB5&$ⵖ蚋⚌⟄忘駈ⵖ蚋遤⚌Ⰼ❡⚌Ꝇ涸宠⚹ⴀ〄挿ⴔ❧Ⰼ椕ⵖ蚋遤⚌剒倝佟瘻岁錞ծ䊨玐ծ䒓〄ծⵖ鸣ծ⣘䎾Ꝇㄤ餘ꆀ盗椚瘝倰涸倝椚䙁ծ䪮助馋⸷ծ⯓鵳呩⢾餻腊⚥㕂ⵖ蚋➃䲀鵳劥㕼ⵖ蚋遤⚌侮⡤宐䎂䲿⼮⟄⿺騗㕂꣢ ❜崨կ1IBSNB5&$ ⵖ蚋⚌鸑鵂⚪㺢涸紺餘⿺侨㶶㯮⡤ծ⠔雳♸崞⸓ծ㹐䨪㹁ⵖ⻊剪⸉瘝⚹暵㹁湡叻纈⡤䲿⣘剣佪涸⥌䜂❜崨䎂〵䎇⚹⣘䎾㉁♸欽䨪䲿⣘㢴庈麤涸❜✽䎂〵կ ǒืሮࢺˊǓ͘ނᎄ 1998ظ/ሆ/ሆ20නӲ/2025ڼ8ڼDŽጺ667Dž րނ˟͊ ິࠅᆶ၌ߢ࠽دߦޡ߾ǖԛऐپጺߢ࠽ںǖԛဇ൶ӥྤግٷন22ᇾࡽ2୍ࡽ3֫ᆰՊǖ100037Add.: 3rd Floor, 2nd Building, No 22, BaiwanzhuangStreet, Xicheng District, Beijing, 100037ࣆۉTelǖ+86-10-63326090࡛ฉTelǖ13917264254 17755450823໋ዝTelǖ18662595387ހਸTelǖ13683598646ኣዝTelǖ18810368957ళཚTelǖ18510064198ฬᄞTelǖ18545558115ྗں൶ஏتǖJ&M Media CorporationࣆۉTelǖ+886-4 2296-5959 ࣷࢇᄽ߾ऐႁࡔ࿋ǖዐڇ࠶ዷዷӸڇ࿋ǖऐႁ߾ᄽ႑တჺ৯ᇾዐࡔऐႁ߾ᄽणཷᆶ၌ࠅິӲڇ࿋ǖୁ߾ײᄽՊडևںǖԛဇ൶ӥྤግٷন22ࡽᆰՊǖ100037 ڎဍᣝ Ҟ˟͊ނր ڎဍಞऋࣹङᗘᄇᜦϤᩐቡ߸և߱ ᦌ۲Ϥ֙ᔵլ߷ڎᅵ๒ணᒬঽᦀ ࣻᔮᖱ มǖঁჱԐޭǖมᛉਚލቧዜბᆗዷՊǖࢲ ৢᛉޭዷՊǖตૢዱࢆ݀ ݤݚՊडևǖ٢ቧলႸ෴ࣜ᫇ቛᇸ 匔ⷶ⍒ⷶ⢆ ǖپߢ࠽ഄǖࡔڤVogel Communications Group GmbH & Co. KGTel: +49 9314182988ǖࡔெGardner Business Media, Inc.Tel: +1 5135278800૧ǖٷᅪFerdinando Salaris Tel: +39 3388285021๗ǖVogel Communications Group AGTel: +41 447227700հનǖRaven Media sp.zo.o. Tel: +48 717823181যਖ਼ǖMM publishing s.r.o Tel: +42 0775245802૧ǖںӎTechnik & Medien Verlagsges.m.b.H.Tel: +43 187683790Ⴅც૧ǖMüszaki Média Kiadó Kft.Tel: +36 203967942ǖࡔGreen World Medida (Thailand) CompanyLimited Tel: +66 27311191ǖࡔࡣMM MaschinenMarkt Korea Co., Ltd.Tel: +82 1084065100 DŽӀᅼಇႾDž ߵӊॐᘀᩤᬈᬈᮻᬈᩤᬈᤉᬈቡழᬈ߱ Քپᬈሮʸ໘ၷʸᗉЋ᭕ ̷сюᰴ ूࠂᰴභᔥੇрမڎ͵ ᳧ ࣼथॴކᗘһޏһᭇҽౄฉౄйౄᴝౄᇼڎౄౄູౄຎູ ್ᇖ໘ѶҧकѶຍ್ѶՔ̈ҪߦѶ ᯱᰏ ᯱ୳ ᯱᆰ ᯱ௴ˌˌ࠵ඐൗϤ߷༿˰ᓍՃ᳁ԾΫᔚᏤˌࠃංסᬝᨷ᭢ၿ༷᩸ᓨࠃဍဍΈᭋဍйဍРဍՔᣝဍ ̈᱐ΈᲞں᱐न᱐අᮊں៙ௌ१ழᓢ ᫆᫂ࡻᭇ˗ӨޅՁҽՁ ̆ห˿ ̆ˇঽ᧧ѸܙභεඅसНसቡूससழᡏဗ࣌ᡏᡏ၊ևևߺևᏕևᥴᤌᥴঃ̈ Պडևۉࣆǖ+86-10-63326091E-mailǖprocess@vogel.com.cnࣆǖۉခޜኁ܁+86-10-63326083 ݀݀ᄽՊडև߾ײ࿋ǖୁڇႜႜ݀ਸࠅాྔࡔྷǖݔႜӲዜǖሆࡔाՔጚჄӲࡽǖISSN 1674Ċ5922ࡔాཥᅃჄӲࡽǖCN 11Ċ5669/Tᆇǖԛձ࡛ื֒ᆇຘᆶ၌ࠅິ ۨॏǖ10ᇮNj ሗڦխणཷدߦޡࡔڤ๕ՊᅳݛӲႹࡗᄽ႑တჺ৯ᇾཚ߾ྔ႑တᆯऐႁ࡛ڦᄽė߾ײĖୁኾPROCESSăInternational Editorial of LiuCheng GongYe is licensed from PROCESS.Ӳำ ǖԨߡॲӲᆶLj࿄ঢ়ሎႹLjփڥገሜăස๚ံ༬ຫLjፕኁཨߡनྺཞ้ኽतྪበĂྲ႑Ăྲձᅜ၎ᆌӲă 1IBSNB5&$ ⵖ蚋⚌錠곸〿 ۉጱሗኾ൩ݡ࿚https://pharm.jgvogel.cn/dzzz/ ᆅߢ࠽Advertiser Index ࡔᆈFLYGERິࠅோᆶ၌݅ߦટޡິࠅᆶ၌ڢ࠶ᄽ༬ዖ߾໒۫࠽ฉ࡛ഔ᮱ํᄽᆶ၌ࠅິટຯҾඇ݅ோDŽཀৄDžᆶ၌ࠅິDECHEMA Ausstellungs-GmbHฉ࡛ᇺҾୁ༹ยԢरᆶ၌ࠅິྰ૬ჯتरຍDŽฉ࡛Džᆶ၌ࠅິኅॿಋጲ੦ᅏᆶ၌ࠅິฉ࡛۫ୄरᆶ၌ࠅິ ฉ࡛৫ᆶୁ༹रᆶ၌ࠅິ45ԎۉጱDŽฉ࡛Džᆶ၌ࠅິ47౷ߦDŽฉ࡛Džஹᅟᆶ၌ࠅິ61ݤ༬DŽዐࡔDžᄱरᆶ၌ࠅິ65ฉ࡛ᅪ݀ஒᄱยԢᆶ၌ࠅິ67ԛࡪଠࡵᇔर݀ቛᆶ၌ࠅິ75ڱఐ߾ᄽยԢDŽฉ࡛Džᆶ၌ࠅິ93ኅॿᇺҾୁ༹ยԢᆶ၌ࠅິ97SieversݴဆᅏDŽྰ૬ჯDž109 ྲႾײ႑ၭ 2025-8 ୁᄽ߾ײ12025-8 ୁᄽ߾ײ1 ੨ࠦޜ༹वჄิׂ࿄ઠڦՔ߇ႠਦݛӄĊĊFE CPSჄิׂဣཥP8 㼓➃暟$PWFS'JHVSF 44ݣ㢜㵹͇㘪⎽ノ⤳͚ᢌ䃳ݘ̻ᮧ㘪ࡃノ⤳䌢 /ዜॆெ၊ڤԕSmart energy management: Identifying loss & driving efficiency in pharma 06ϻ侹ბݝ⩌ϔВڕ䨫᱙ౌ݈ࡃ䛺ൾݣ㢜㵹͇⩌ᔮ/ݤݚ٢From lab to production: reshaping pharma with end-to-end local innovation ϻ侹ბݝ⩌ϔFrom Lab to Prodution 482025ݣ㢜㵹͇❴ݯ⩌ϔ䃫ิ䄰ⵁܳᲽ 喟ᮧࡃ䒙ಸ侞ߕ̸⮱᩵⢴ࡴ㏔̻ጒ㞧݈/ԨՊडև2025 Tablet manufacturing survey: Digital transformation drives efficiency &innovation 遤⚌錜㻋*OEVTUSZ0CTFSWBUJPO 102025࣌᫆ߋͫߌ䕍䃧ಈݣ䔈ٵݯݣ㢜ࣷధҀ/ݤݚ٢2025 API & Solid Dosage Advanced Manufacturing Forum wraps successfully14≲䄵⩌➖ࡨ㢜Ю͇ጒ㞧䃫ิ䛴䉚ڕ≮⼸ノ⤳/ႹManaging the full lifecycle of biopharma equipment procurement20 ࣌᫆㢜+ݯݣ̭Ҁࡃ⩌ϔЮ͇䃫ิ⩌পকႶڕノ⤳Ҁ㈨Ჱᐧ̻䌢/Ⴘॺ࿀Building & implementing a lifecycle safety management system for integratedAPI-drug product facilities 56Ꭰぶцѡڠ㈨᭜ߌ⮱ڠ䩛㉍/Anke Geipel-KernEqual partnership is key to success 59۳ㆶ᱘䙺ᐭ̻ࣾ侹ბߎ/ࡔ༬ዐݤPrecision powder formulation: Development & lab services 62䔋㐚ݣ䕍ឭᱜᏁ⩕⣝⟣̻ᠾᝅ/ݤݚ٢Continuous manufacturing: Current applications & hurdles 暵ⵆ瘻ⴢ4QFDJBM'FBUVSF ݣ㢜ጒ⼸̻䃫ิPharma Engineering and Equipment 66䔋㐚ݣ䕍ຯ҂⣝ϻᐭࣾݝ⩌ϔ⮱䔋㐚ࡃ̻▢≨ࡃ /Marten KlukkertAchieving seamless & flexible transition from development to production viacontinuous manufacturing /०ਬᚴݐࢆ٢૬ᄊMulti-layer risk control design for high-potency API facilities 29⩌➖ࡨ㢜ࢯᝬ䰣ᭌጒ⼸⮱ڕ䓴⼸ノ⤳ⵁ⾣ 68ࢸ❴ᱧ̻ㆶ᱘Ⱑࢸጒ㞧⮱хࡃ䔯䙺ᣏ䃕/٢ඵ֍Optimizing tablet presses for direct powder compression /ዬᅫݰೝૢגኾฬ࿀ࡔቶۭ࿔ݚٳגಧࡓManaging small-scale projects in biopharma plants: A full-lifecycle approach 32ݣ㢜Ю͇ᬍ㣹ݯݣ䒓䬡ज㻳ࡃ䃫䃎হノ⤳ᣏ㉏/ᇺຏࢆVisual design & management for sterile drug product suites VPEIF2025䃬䄵VPEIF2025 Interviews 72Вጒ৮䉕䨥ᅞݣ㢜㷲ิ⮱͚ప߈䛼/ݤݚ٢Precision engineering: Building China's pharma equipment strength 36ധλISPE DIMMಸᄦᵤ᱙Ю͇ᢛႹ᪡ᕔ⛌Ꮣ⣝⟣⮱ ᣏ⾣/ࢲ࿋᪻Exploration of the data integrity maturity status of pharmaceutical enterprisesbased on the ISPE DIMM model 76䉸㘪ࡨ㢜᱗Გ喑ڞまᮧ䕍ᴴᱳ/ݤݚ٢Enabling pharma's future, building smart manufacturing benchmarks 78ι䒪݈㱂अ喑䛺ൾݣ㢜⩌ϔ߈/ݤݚ٢Two decades of innovation: Redefining pharmaceutical production Contents 鵂玐䪮助♸䊨蒌 1SPDFTT5FDIOJRVFT 82ᬍ㣹ݣݯݣ㢜ጒ㞧ឭᱜᣏ⾣/ഽࢡ็ଠୄṩؾቤᨤଘExploration of sterile formulation pharmaceutical process technology87㑀ᣔ䛷ᓛͥ3Dក࢝ಸጒ㞧̻䛷㢜㵹᪴䄰ᣔ/߯ቧჯӣল3D-printed controlled-release pellets: Fabrication & release profile tuning90 ͚㢜䷄ㆿݯ⩌ϔ͚⮱⣝Аࡃጒ㞧ᩦ䕍/ஆႌࡣModernizing traditional Chinese medicine granule production95䊲䛺߈ឭᱜౕ⣜ධ䶳ഌ⮱Ꮑ⩕/ԐࢤApplication of high-gravity technology in the environmental field98≲䄵ݣ㢜⩌ϔ͚࢞რ➖᫆⮱䭟៑ゃ⪒/༚၄ଵቧဪBrief discussion
