东曜药业-B2025年中期报告

BioDlink International Company Limited 中 期 報 告2025 231317182021223649 1617 33191918 120 www.biodlink.com 1875 ESG • 22 CDMOCDMO··ADCCDMO 2025ADCCDMOADCADCADCCDMO 20256 3016ADC1416912273%ADC12 CDMO ®688136.SH202520256 30GMP® 20223-B6622.HKTAB014(wAMD)TAB014(MAH)TAB014wAMDTAB014wAMD2025 6 123.2(TAB014)TAB014(wAMD) CDMO 20256 30 1 •489,1406%397,9091%CDMO/CMO77,30132% ADCCDMOGMPPPQADCADCADC •202534,83025% •4,06287% OSHydroTrioOSADCHydroTrioDAR 2CDMO –2.1·ADC ··ADCADCCDMOCDMOXDCDNAIND11CDMO BDKcell®(CHOk1)INDFab –2.2 CDMO GL-DisacLink™ ADCFc 2.3GMP –2.4 50,000 m2422ADC54303,000ADC960530 ICHQ10FDAALOCA+NMPAFDAEMAGMPGMPGMP202563060GMPQPGMPGMPPMDA(DMS)(ERP)(EMS)VAISALA(LIMS) –2.5CDMO CDMO1520256 306045%CDMO5247%87%ADC77% CDMO20256 30 18A.05 2025397,90920256303526GMP ® ®20212025630®Avastin®1002030490202120307.6%2030184202120308.3%®2022 ® ®2021531NMPA2021®20222025630 •20255BioProcess International EuropeGMPCDMOCDMO ADCXDC CDMO •2025521st Annual PEGSBoston 2025ADCADC 2025 •2025215(15th World ADC London)GL-DisaLink® •202562025PlusDisacLinkOne-step cys •202542025XDC··ADCCDMO •20256BioPlusCMCBiotech •20254AACRADCXDCCDMO •202562025 CBA-ChinaADCXDCADCXDCADC CDMOCDMO 2025ADCASCO100ADCCDMOCDMO 2025489,1402024520,60331,4636%20254,062202431,55927,49787%202535,628202446,059202534,725202432,1052025277,4452024276,482 CDMO 202535,628202446,05910,431CDMO 2025277,4452024276,482963 CDMO/CMO 2025397,9092024400,4002,491 2025CDMO/CMO77,3012024113,79136,490CDMO/CMO136,101143,6957,594CDMO/CMO 202534,725202432,1052,620 20252024 202550920249,4518,9422024 20254,062202431,559 20253,42820241,5451,883 2025630731,6822024729,6552,027 20256 30383,9822024381,2562,726 20251,25020242,182932 202534,830202427,8017,029CDMO26,506202468,78442,2785,065202436,2092025 20256,36620243,8812,485 2025630396,118202412 31394,013469,050202412 31299,05014 20256 3060420256 30 20256 300.52024 12 310.5 202111 91.8202112 3183,500202112 3120256 307,283 (1) 2025106,705202496,742 2021ADC20256 302,841 20256 30 2025 20256 30 20256 30 1 TOT BIOPHARM International Company Limited200912 433191918 CDMOCMO 201911 8 20258 12 2 2.1 20256 3034 202412 31 20256 30202412 31622436 622662(3)63202412 31 2 2.1 (a) (b) 3 3.1 20241231 202412 31 3.2 3 3.3 13 1 22 33 20256 30202412 31 • • 20256 3020246 30 20256 3012 320246 30 4 2024 5 (a) CDMO/CMO (b) 5 (d) (e) 2017110 84,500,00020256 3055,500,00020256 30202463029,000,000 2022110 30,000,00020256 3030,000,00020256 305,000,00020246 30 CDMO/CMO115 5 (f) 202520246 30 6 7 8 9 (a) (b) 202563020246 3020256 300.0120246300.04 11 (a) 1590 20256 30202412 31 (b) 11 (b) 12 (a)202412 31CDMO14,219,0002026120256 30 13 3220256 30202412 3147,590,948 14 20256 30202412 31 16 20256 30202412 31 17 (a) 18 202520246 3020256 30202412 31 (a) Vivo HK Limited (b) (i) 20256 30XVXV78352 (1)L(2)20256 30772,787,887(3)(4)Teeroy Limited 20256 30XV78352 20256 30XV23336 (1)L (2)20256 30772,787,887 (3)213,311,7007,646,300 (4)Advantech Capital Investment V Limited49,136,800Advantech CapitalInvestment V LimitedAdvantech Capital II Master Investment LimitedAdvantech Capital II L.P.Advantech Capital II L.P.Advantech Capital II L.P.Advantech Capital Partners II LimitedAdvantech Capital Partners II LimitedAdvantech Capital II Master Investment LimitedAdvantech Capital II L.P.Advantech Capital Partners IILimitedAdvantech Capital Investment V Limited (5)Chengwei Evergreen Capital, L.P.56,573,500Chengwei Evergreen Capital, L.P.Chengwei Evergreen Capital, L.P.Chengwei Evergreen Management, LLCChengwei Evergreen Management, LLCChengwei Evergreen Capital, L.P. (6)Vivo Capital Fund VIII, L.P.90,718,100Vivo Capital Surplus Fund VIII, L.P.12,526,900Vivo Capital Fund VIII, L.P.Vivo Capital Surplus Fund VIII, L.P.Vivo CapitalVivo CapitalVivo Capital VIII, LLCVivo Capital LLCVivo CapitalVivo Capital VIII, LLCVivo Capital VIII, LLCVivo Capital LLCVivo Capital (7)116,250,000 (8)Tricor Trust (Hong Kong) Limited202020205 2938,993,566 20256 30XV23336 20132 20201712 11201812 2020193 1220194 1620197 22 V-36V-47202426 20256 30 (1)(i)(ii)(iii)1.0020143 30.286V-37V-38 (2)20223 1 (3)7,819,6001.01% 87,558,390202212 307,558,390 2020 20205 292020(i)(ii)2020202020207 29202112 23202211 12020105 20256 3020205,274,9130.68%202412315,274,9132020Tricor Trust (Hong Kong) Limited13,141,5912024123113,141,59120227 292020202420202024 202057,000,0005,700,00020202021202014,250,000202112232020202112 23(1)(2)(3) 202020208 382120211223(1)(2)(3)202211 1(1)(2)(3)(4)202212 8202426 2020529202020208431,413,7962020122830,466,697202112 232813,700,000202112 3013,700,0002022111 2020 20256 302020 (1) (2)(i)20205 29(ii)202112 23202211 1 12772,787(3)12772,787 2024 20245 292024(i)(ii)2020202462620242024109 20256 302024 202420245 301225 202477,278,78810.00%2024(i)3,863,939(ii)(1)127,727,878(2) 20256 302025630 20256 3018 2022531150,000,0003.15 2