恒瑞医药2025中期报告
江 蘇 恒 瑞 醫 藥 股 份 有 限 公 司Jiangsu Hengrui Pharmaceuticals Co., Ltd.（ 於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司 ）股份代號:1276 2 4 5 7 21 32 34 36 38 40 57 38 7 33191920 H 1617 200010 18 20255 23 2920 15 97927 45 50037 www.hengrui.com A600276 H01276 2019(Pharm Exec)502025Citeline202520245002312202450 ADC 1.2.3.2018 2025 202515,761.215.9%4,450.129.7%3,871.23,227.9 1. 20259,560.960.7%7,569.8 2. MerckSharp & Dohme 200.0IDEAYA Biosciences 75.0 3. PROTACADCDACAPCAOCAI 15ADCADC10ADC(SHR-A1811)9CDE 1261(I)/(II)631115NMPA10III22II15I MAABLAFDAFDA(SHR-A1811)(SHR-1316)FDA 124622 15(ASCO)2025ASCO72452736 2025(ADA)918 255PCT3341442,864PCT7371,125797 173JAMAAnnals of OncologyCancer CellJournal ofClinical OncologyLancet Oncology•1,35117≥20 20253Merck Sharp & Dohme(a) (Lp(a))HRS-5346Merck Sharp & Dohme200.01,770.020254Merck KGaA, Darmstadt, GermanySHR7280GnRHMerckKGaA, Darmstadt, Germany15.0 3025,000200,0001,5002 2314261 20246 3013,600.715.9%20256 3015,761.2(i)(ii)MerckSharp & Dohme200.0IDEAYA Biosciences75.0 99.5%20246 3099.4%9,560.960.7%7,569.848.0%55.3% 20246 3011,727.416.4%20256 3013,646.220246 3086.2%20256 3086.6% 20246 305,227.710.9%20256 305,799.3202463038.4%20256 3036.8% 20246 303,037.86.3%20256 303,227.920246 3022.3%20256 3020.5% 20246 303,428.129.9%20256 304,454.720246 3025.2%20256 3028.3%4,450.129.7% 202412 3150,135.625.4%20256 3062,893.5202412 3124,802.545.5%20256 3036,094.0202412 3146,090.328.1%20256 3059,029.8H 20256 304,300.51,267.7 20256 301,084.7438.9 20256 308,039.5H 12 20256 3035,542.62024123121,636.2 20256 304,300.520246303,032.8 20256306.1%202412318.1% 20256 30 20256 30 20256 3027.92024123113.4 20256 30 20256 30 20256 3020,5603,686.023.4% 20229 820249 6202220232024AA A17.01(1)(b)17.12A202512 31 (ESG) ESG ESGESG 20258MSCI Inc.AAESGAAAAAESG 2025 13.51B(1) 20256 30XV(i)XV78(ii)352(iii)C3 1. (1)(2)20256 306,637,199,8746,379,002,274A258,197,600H(3)20256 30(i)1,538,184,187A(ii)89.2%A 2. (1)20256 30(i)48.5%28.0%(ii)89.2% (2)20256 30(i)40.0%(ii)50.0% 20256 30XV(i)XV78(ii)352(iii) 20256 30XV23336 GIC Private LimitedJPMorgan Chase & Co. (1)20256 306,637,199,8746,379,002,274A258,197,600H (2)89.2%A1,538,184,187 (3)79.17%100%99.00%99.00% (4)17,439,774JPMorgan Chase Bank, National AssociationJPM, NA400J.P. Morgan SE2,500,650622,550J.P. Morgan Securities PlcJPM Securities Plc9,273,600JPMorgan Asset Management (Asia Pacific)LimitedJPM AM AP202,600JPMorgan Asset Management (Taiwan) LimitedJPM AM Taiwan380,200J.P. Morgan Securities LLCJPM SecuritiesJ.P. Morgan SEJ.P. Morgan International Finance LimitedJPM FinanceJPM FinanceJPMorgan Chase & Co.JPM, NAJPM Securities PlcJPMorgan Chase & Co.J.P.Morgan Capital Holdings LimitedJ.P. Morgan Capital Holdings LimitedJPM FinanceJPMAM APJPM AM Taiwan JPMorgan Asset Management (Asia) Inc.JPMorgan Asset Management (Asia) Inc.JPMorganAsset Management Holdings Inc.JPMorgan Asset Management Holdings Inc.JPMorgan Chase & Co.JPMorgan ChaseHoldings LLCJPM HoldingsJPM SecuritiesJPMorgan Chase & Co.J.P. Morgan Broker-Dealer Holdings Inc.J.P. Morgan Broker-Dealer Holdings Inc.JPM HoldingsJPMorgan Chase & Co.JPMorgan Chase & Co.17,439,774622,550 (5)Morgan Stanley & Co. International plcMSCIMSCIMorgan Stanley Investments (UK)Morgan StanleyInvestments (UK)Morgan Stanley International LimitedMSILMSILMorgan Stanley International Holdings Inc.Morgan Stanley International Holdings Inc.Morgan Stanley InternationalHoldings Inc.13,471,200 (6)18,214,200Capital Research and Management CompanyCRMC1,683,600Capital International, Inc.188,200Capital International SarlCRMCThe Capital Group Companies, Inc.TCGCCapital InternationalSarlCapital International, Inc.Capital Group International, Inc.Capital Group International, Inc.CRMCCRMCTCGCThe Capital Group Companies, Inc. (7)9,432,200UBS Asset Management (Europe) S.A.UBS Europe4,692,000UBS Asset Management (HongKong) LtdUBS HK3,410,400UBS Asset Management (UK) LimitedUBS UK700,871UBS AG65,800UBS Fund Management (Switzerland) AGUBS Switzerland58,800UBS Asset Management (Singapore) LtdUBSSingaporeUBS EuropeUBS HKUBS UKUBS AGUBS SwitzerlandUBS SingaporeUBS Group AGUBSGroup AG (8)7,037,400Cordial Solar Limited5,897,341Boyu Capital Opportunities Master FundBCOMF1,140,059Boyu Capital Vantage Master FundBCVMFCordial Solar LimitedBCOMF83.80%BCOMFBCVMFBoyu Capital Investment Management LimitedBCIMBCIMBoyu Capital Group Holdings Ltd.Boyu CapitalGroup Holdings Ltd.Boyu Group, LLCBoyu Group, LLCXYXY Holdings Ltd.45.70%XYXY Holdings Ltd. (9)7,054,049Wellington Management International Ltd.Wellington International2,369,000WellingtonManagement Hong Kong LtdWellington Hong Kong3,692,684Wellington Management Company LLPWellington MCLLPWellington MC LLPWellington Investment Advisors Holdings LLPWellington Advisors99.99%WellingtonHong KongWellington International Wellington Management Global Holdings, Ltd.Wellington MGHWellington MGHWellington Advisors94.10%Wellington AdvisorsWellington Group Holdi
