新生儿和儿童健康方案和研究的风险分层分析，会议报告，瑞士日内瓦，2024年3月12日至14日

programmes and research in newborn and child health Meeting Report Geneva, Switzerland12–14 March 2024 ©World Health Organization 2025 Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO licence(CC BY-NC-SA 3.0 IGO;https://creativecommons.org/licenses/by-nc-sa/3.0/igo). Under the terms of this licence, you may copy, redistribute and adapt the work for non-commercial purposes, provided the work is appropriatelycited, as indicated below. In any use of this work, there should be no suggestion that WHO endorses any specific organization, products orservices. The use of the WHO logo is not permitted. If you adapt the work, then you must license your work under the same or equivalent CreativeCommons licence. If you create a translation of this work, you should add the following disclaimer along with the suggested citation: “Thistranslation was not created by the World Health Organization (WHO). WHO is not responsible for the content or accuracy of this translation. Theoriginal English edition shall be the binding and authentic edition”. Any mediation relating to disputes arising under the licence shall be conducted in accordance with the mediation rules of the World IntellectualProperty Organization (http://www.wipo.int/amc/en/mediation/rules/). Suggested citation.Risk stratification analyses for programmes and research in newborn and child health: meeting report, Geneva, Switzerland,12-14 March 2024. Geneva: World Health Organization; 2025.https://doi.org/10.2471/B09138. Licence:CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data.CIP data are available athttps://iris.who.int/. Sales, rights and licensing.To purchase WHO publications, seehttps://www.who.int/publications/book-orders. To submit requests forcommercial use and queries on rights and licensing, seehttps://www.who.int/copyright. Third-party materials.If you wish to reuse material from this work that is attributed to a third party, such as tables, figures or images, it is yourresponsibility to determine whether permission is needed for that reuse and to obtain permission from the copyright holder. The risk of claimsresulting from infringement of any third-party-owned component in the work rests solely with the user. General disclaimers.The designations employed and the presentation of the material in this publication do not imply the expression of anyopinion whatsoever on the part of WHO concerning the legal status of any country, territory, city or area or of its authorities, or concerning thedelimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet befull agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by WHOin preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products aredistinguished by initial capital letters. All reasonable precautions have been taken by WHO to verify the information contained in this publication. However, the published material isbeing distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material lieswith the reader. In no event shall WHO be liable for damages arising from its use. Contents Introduction1WHO Child Mortality Risk Stratification Multi-Country Pooled Cohort2Analysis approach2Findings3Summary of main findings and main messages4WHO guidelines and clinical tools / approaches5Risk differentiated care6Intervention packages9Wrap up10Agenda12Participants15Annex: Feedback slides from break out groups: Risk-differentiated care17 Introduction In 2021, WHO Department of Maternal, Newborn,Child and Adolescent Health and Ageing (MCA) invitedresearch teams with relevant data to participate in aRisk Stratification Working Group (RSWG). The aim wasto jointly design and implement a set of analyses thatwould examine individual and cumulative risks for all-cause mortality, and impaired growth or developmentin newborns and children. As a result, 33 datasetswere pooled to establish the WHOChild Mortality RiskStratification Multi-Country Cohort dataset. findings presented and discussions that followed.Summaries follow the structure of agenda includingfeedback from the break-out sessions (Annex). Meeting objectives 1.To review findings of the WHO Child Mortality RiskStratification Multi-Country Cohort pooled analyses2.To consider how risk-differentiated care approachesmight reduce infant and child mortality throughimproved clinical decision pathways and healthprogrammes.3.To identify research needs and interventionpackages for testing. In 2022 and 2023, a set of pooled analyses wereconducted with technical support from the Universityof Bergen, Norway. Main findings were agreed by theRSWG and will be submitted for publication in peer-revi