变革处方：妇女健康研究的政策建议（英）

DisclaimerThis document is published by theWorld Economic Forum as a contribution to a project,insight area or interaction. The findings, interpretations andconclusions expressed herein are a result of a collaborativeprocess facilitated and endorsed by the World EconomicForum but whose results do not necessarily represent theviews of the World Economic Forum, nor the entirety of itsMembers, Partners or other stakeholders.©2025 World Economic Forum. All rights reserved. No partof this publication may be reproduced or transmitted in anyform or by any means, including photocopying and recording,or by any information storage and retrieval system.ContentsForewordExecutive summaryIntroduction: The case for women’s health policy transformation1 Unlock innovation in women’s health1.1 Women’s health is underfunded and under-researched1.2 Success in orphan and paediatric diseases:Incentives drive investment and innovation1.3 Policy recommendations to unlock innovation inwomen’s health2 Expand the inclusion of women in clinical trials2.1 Women remain under-represented in clinical trials2.2 Success in paediatrics: Requirements and incentivesdrive inclusion2.3 Recent guidelines and initiatives start to focus on inclusion2.4 Policy recommendations to expand the inclusion of womenin clinical trials3 Enhance disaggregation of clinical trial data3.1 Policy recommendations to enhance disaggregation ofclinical trial data4 Design clinical trials with women in mind4.1 Policy recommendations to design clinical trials withwomen in mind5 Deepen insights into sex-specific differences5.1 Policy recommendations to deepen insights intosex-specific differencesConclusionContributorsAcknowledgementsEndnotes 346991010121213131416161818202022232325Prescription for Change:Policy Recommendations for Women’s Health Research ForewordThe World Economic Forum’s Global Alliance forWomen’s Health, in partnership with Kearney andthe Gates Foundation, is pleased to present thiswhite paper proposing key policy recommendationsto protect improvements already made in women’shealth science and innovation and to promotefurther progress.Addressing the women’s health research gap isnot only an ethical imperative but also a criticalstep towards transforming global health outcomes.Women’s health has historically been under-researched and underfunded, leading to gaps inknowledge and innovation. Despite comprisinghalf the world’s population, women have also beenunder-represented in clinical research, resultingin significant disparities in the understanding ofmen’s and women’s physiology. These disparitieshave far-reaching implications, influencingdiagnosis, treatments and ultimately healthoutcomes for women.This existing gap in women’s health research is inline with the fact that women live in poor healthfor 25% more of their lives compared to men,according to a 2024 report.1Closing this gapcould yield 75 million disability-adjusted life yearsannually – the equivalent of adding seven healthydays per year per woman – and unlock $1 trillionin annual global GDP by 2040. While the economicbenefits are impressive, improving women’s healthis the real win, with lasting positive repercussionsShyam BishenHead, Centre for Healthand Healthcare; Member ofthe Executive Committee,World Economic ForumPrescription for Change:Policy Recommendations for Women’s Health Research for society. The time has come for stakeholders toaddress the drivers of this gap, improving the livesof women while strengthening communities andThis paper addresses the policy changesneeded to establish a more robust, safe andinclusive approach to women’s health scienceand innovation. We strongly believe that drivinginnovation in women’s health can improve thestatistics and lead to more women-focused clinicalresearch. Furthermore, it makes the case forincluding women from diverse racial, ethnic and agegroups in clinical trials to ensure such trials betterreflect the populations they aim to serve.The policy recommendations presented in thispaper aim to address the gap in women’s healthresearch. By promoting a more inclusive approachto research, society can advance science througha deeper understanding of women’s physiology,thereby improving safety and outcomes for womenwhile advancing knowledge on health and medicineLooking to the future, it is imperative thatpolicy-makers, healthcare leaders and otherstakeholders join forces to uphold women’s healthas a cornerstone of medical progress. The visionoutlined in this white paper provides a strategicpath to closing the women’s health research gapand advancing sex-specific medicine.Paula Bellostas MuguerzaSenior Partner, Global Lead,Healthcare and Life Sciences,Kearney3 economies worldwide.for all. Executive summaryDespite living an average of five years longer thanmen, women spend 25% more of their lives in poorhealth or with some degree of disability.2Addressingthis burden could improve the length and qualityof life for millions of women while also boost