Safety Shot Inc. American Depositary Share Prospectus (Version as of May 14, 2025)

(To the Prospectus Dated November 9, 2022) Safety Shot, Inc. 695,410shares of Common Stock We are offering 696,410 shares of Common Stock, par value $0.001 per share (the “Common Stocks”). The shares ofCommon Stock will be sold at a negotiated price of $0.3595 pursuant to this prospectus supplement, the accompanying prospectus and The shares of Common Stock are being offered directly to investors without a placement agent or underwriter. We are notpaying placement agent fees or underwriting discounts in connection with the offering. Our Common Stock is listed for trading on the Nasdaq Capital Market (“Nasdaq”) under the symbol “SHOT”. The closingprice of our Common Stocks on May 13, 2025, as reported by Nasdaq, was $0.4494 per share. As of May 13, 2025, the aggregate market value of our outstanding Common Stocks held by non-affiliates was approximately$28,675,546 based on 63,808,513 shares of Common Stock held by non-affiliates on such date and based on the last reported saleprice of our Common Stocks on Nasdaq on March 18, 2025, (a date that will be within 60 days of the date of this prospectussupplement) of $0.53 per share. In no event will we sell securities pursuant to a Registration Statement on Form S-3 in a publicprimary offering with value exceeding more than one-third of our public float in any 12-month calendar period so long as our publicfloat remains below $75 million and General Instruction I.B.6 of Registration Statement on Form S-3 continues to apply to us. As of Investing in our Common Stocks involves a high degree of risk, including that the trading price of our CommonStocks has been subject to volatility and investors in this offering may not be able to sell their Common Stocks above the actualoffering price or at all. Before making an investment decision, please read the information under the heading “Risk Factors” NEITHERTHE SECURITIES AND EXCHANGE COMMISSION(THE“SEC”)NOR ANY STATE ORCANADIAN SECURITIES REGULATOR HAS APPROVED OR DISAPPROVED OF THE SECURITIES OFFERED Aggregate gross proceeds from this offering will be approximately $250,000. See “Plan of Distribution” beginning on pageS-10 of this prospectus supplement for more information regarding fees and expenses of this offering. Delivery of the shares of Common Stock offered hereby is expected to be made on or about May 15, 2025, subject to thesatisfaction of certain closing conditions. Prospectus Supplement dated May 14, 2025. Prospectus Supplement Prospectus ABOUT THIS PROSPECTUS SUPPLEMENT General Advisory This document is in two parts. The first part is this prospectus supplement, which describes the specific terms of this offeringand also adds to, and updates information contained in the accompanying prospectus and the documents incorporated by referenceherein and therein. The second part, the accompanying prospectus, provides more general information, some of which may not applyto this offering. Generally, when we refer to this prospectus, we are referring to this prospectus supplement and the accompanyingprospectus combined. To the extent there is a conflict between the information contained in this prospectus supplement and theinformation contained in the accompanying prospectus or any document incorporated by reference herein or therein filed prior to the We further note that the representations, warranties and covenants made by us in any agreement that is filed as an exhibit toany document that is incorporated by reference herein were made solely for the benefit of the parties to such agreement, including, insome cases, for the purpose of allocating risk among the parties to such agreements, and should not be deemed to be a representation, You should rely only on the information contained in or incorporated by reference in this prospectus supplement and theaccompanying prospectus. We have not, authorized anyone to provide you with different information. If anyone provides you withdifferent or inconsistent information, you should not rely on it. We are not making an offer to sell these securities in any jurisdictionwhere the offer or sale is not permitted. You should assume that the information in this prospectus supplement, the accompanyingprospectus, and the documents incorporated by reference herein and therein, is accurate only as of the date of those respectivedocuments. Our business, financial condition, results of operations and prospects may have changed since those dates. You should read We are offering to sell, and seeking offers to buy, securities only in jurisdictions where offers and sales are permitted. Thedistribution of this prospectus supplement and the accompanying prospectus and the offering of securities in certain jurisdictions maybe restricted by law. Persons outside the United States who come into possession of this prospectus supplement and the accompanyingprospectus must inform themselves about, and observe any restrictions relating to, the offering of securities and the distribut