华领医药-B年报 2024

(於開曼群島註冊成立的股份有限公司 )股份代號 :2552 2552 (321,071)970,192 20241231418.0250.159.8108.020241231 300,179167,754 Robert Taylor NELSEN612010423201851120108 1994NelsenARCHVenturePartners30Nelsen2018620247213720199PRIMEMedicine202210PRME20189SanaBiotechnologySANA20188LyellImmunopharmLYEL20171Vir Biotechnology Inc.VIR2021320224Renovation Healthcare Acquisition Corp.REVH20158201810SiennaBiopharmaceuticals,Inc.SNNA2012820186SyrosPharmaceuticals,Inc.SYRS2013820183JunoTherapeutics,Inc.JUNO20061201412KYTHERABiopharmaceuticals,Inc.KYTH20071220176AgiosPharmaceuticalsInc.AGIO2013920163SageTherapeutics,Inc.SAGE20142201511BellerophonTherapeutics,Inc.BLPH19941120045AdolorCorporationADLR1998620068Illumina,Inc.ILMN2007920146FateTherapeutics,Inc.FATE2000720137NeurogesX,Inc.NGSX201111202012UnityBiotechnology,Inc.UBX2018820216KarunaTherapeuticsInc.KRTX2017620216BeamTherapeuticsInc.BEAM2015520226DenaliTherapeutics,Inc.DNLI2012629NGSX(OTC)Nelsen KellerAlexionPharmaceuticals,Inc.ALXN20091220155NKBP20088201112HBM Biomed China Partners 2018720206 201362010720116200972010620072006 Robert Taylor NELSENFangxin LI (3)2019410JaneXingfangHONG100,000ChenFamilyInvestments,LLCChen Family Investments, LLC1100%Jane Xingfang HONGChen Family Investments, LLC10,000,000 (4)The George and Ann Lin 2005 Trustthe George and Ann Lin 2005 Trust (5)ARCH Venture Partners VII, LLCRobert Taylor NELSENARCH Venture Partners VII, L.P..NELSENARCH Venture Fund VII, L.P. 1.ARCH Venture Fund VII, L.P.ARCH Venture Fund VII, L.P.ARCH Venture Partners VII, L.P.ARCH Venture Partners VII, L.P.ARCH Venture Partners VII, LLCARCH Venture Partners VII, LLCRobertTaylorNELSENKeithLawrenceCRANDELLClintonWhitewoodBYBEEARCH Venture Partners VII, L.P.ARCH Venture Partners VII, LLCRobert Taylor NELSENKeith LawrenceCRANDELLClinton Whitewood BYBEEARCH Venture Fund VII, L.P.ARCHVenture Fund VII, L.P.Robert Taylor NELSENKeith Lawrence CRANDELLClinton WhitewoodBYBEE 2.Venrock Associates V, L.P.Venrock Associates V, L.P.Venrock Management V, LLCVenrock Management V, LLCVenrockManagementV,LLCVenrock Management V, LLC 3.Wuxi Pharmatech Healthcare Fund I L.P.Wuxi Pharmatech Fund I General Partner L.P.WuxiPharmatechInvestments(Cayman)Inc.Wuxi Pharmatech Investments (Cayman) Inc.Wuxi Pharmatech Investment Holdings (Cayman) Inc.Wuxi Pharmatech Investment Holdings (Cayman) Inc.Wuxi AppTec International Holdings LimitedWuxi AppTec International Holdings Limited 5.Jane Xingfang HONG11,221,72524,079,000HONG2.39% 2019410JaneXingfangHONG100,000ChenFamilyInvestments,LLCChenFamilyInvestments,LLC100%1HONGChenFamily Investments, LLC10,000,000 202110136,000,000Jane Xingfang HONGHONG 6.L 1. •Dorzagliatin 華堂寧® CROCMOSMO 201112Hoffmann-La Roche Inc.F. Hoffmann-La Roche Ltd. 20241231•William Robert KELLER 202411 Robert Taylor NELSENFangxin LI Robert Taylor NELSENA/BFangxin LIA/B (i)(ii)(iii) 2,500,00002,500,0013,000,00023,000,0013,500,00013,500,0014,000,00004,000,0014,500,00014,500,0015,000,00015,000,0002 200506Chengde WANG+86 (21) 3810 1803ir@ huamedicine.com 2024 1. 2. 2. 3. 3.1 3.2 3.2 3. 3. 3.2 3. 3. 3.2 3. 3. 3. 3. A91,38335,036B49,92811,332C39,9841D110,701 255,87376,61019–255,89276,610 8. 34,58336,238 22. 23. 25. 1,243,4991,339,153 27. 123120242023 28. 2014124201882611,221,7250.070.4920184325,592,4050.4713(v)20133252018666,733,3200.070.472013325201882613,789,6930.070.47201391220185114,447,0000.070.47 201938202333124,079,0003.408.86620193820233311,500,0003.628.86613(v)20193820233311,900,0003.408.866201892820235824,707,7482.9688.866201938200,0008.866 111231 2014200,000––––200,00020161,500,000––––1,500,00020171,500,000––––1,500,00020188,221,725––––8,221,725 20231120231231 20133,654,000–(3,654,000)–––20143,730,500–(1,500,000)––2,230,50020166,875,000–(1,200,000)––5,675,00020175,004,000–(254,000)–(1,200,000)3,550,000201819,352,293–(2,903,320)–(2,803,960)13,645,013 20131,550,000–(900,000)–(650,000)–2014150,000––––150,00020163,322,000––––3,322,00020181,125,000––––1,125,000 1320241120231231 33. 37. 2023115,921,640260,651(4,143,730)2,038,561––(21,530)(21,530)9,187––9,187–23,911–23,911202312315,930,827284,562(4,165,260)2,050,129––(19,602)(19,602)1,577––1,577–11,841–11,841202412315,932,404296,403(4,184,862)2,043,945 1,243,499,0002025 2018914 0.001