Shattuck Labs Inc 2024年度报告

FORM10-K ☒ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934For the fiscal year endedDecember31, 2024OR☐TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934For the transition period fromtoCommission File Number:001-39593 Shattuck Labs, Inc. (Exact name of registrant as specified in its charter) 81-2575858(I.R.S. EmployerIdentification Number) Delaware 500 W. 5th Street,Suite 1200Austin,TX78701(512)900-4690 (Address of principal executive offices including zip code)Former name, former address and former fiscal year, if changed since last report: N/A Securities registered pursuant to Section 12(b) of the Exchange Act: Securities registered pursuant to Section 12(g) of the Exchange Act: None Indicate by a check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes☐No☒ Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filingrequirements for the past 90 days.Yes☒No☐ Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 ofRegulation S-T (§ 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).Yes☒No☐ Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or anemerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company”in Rule 12b-2 of the Exchange Act. Accelerated filer☐Smaller reporting company☒Emerging growth company☒ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with anynew or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.☐ Indicate by check mark whether the registrant has filed a report on and attestation to its management’s assessment of the effectiveness of its internalcontrol over financial reporting under Section 404(b) of the Sarbanes-Oxley Act (15 U.S.C. 7262(b)) by the registered public accounting firm that prepared orissued its audit report.☐ If securities are registered pursuant to Section 12(b) of the Act, indicate by check mark whether financial statements of the registrant included in thefiling reflect the correction of an error to previously issued financial statements.☐ Indicate by check mark whether any of those error corrections are restatements that required a recovery analysis of incentive-based compensationreceived by any of the registrant’s executive officers during the relevant recovery period pursuant to §240.10D-1(b).☐ Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes☐No☒ The aggregate market value of the voting and non-voting common equity held by non-affiliates of the registrant as of June 28, 2024, was approximately$102,096,000based on the closing price on The Nasdaq Global Select Market reported for such date. Shares of common stock held by each officer and directorand by each person who is known to own 10% or more of the outstanding common stock have been excluded as such persons may be deemed to be affiliates ofthe registrant. This determination of affiliate status is not necessarily a conclusive determination for other purposes. As of March17, 2025, the registrant had47,899,240shares of common stock, $0.0001 par value per share, outstanding. Documents Incorporated by Reference The information required by Part III of this Annual Report, to the extent not set forth herein, is incorporated by reference to the registrant’s definitiveproxy statement relating to the Annual Meeting of Stockholders to be held in 2025, which is expected to be filed with the Securities and Exchange Commissionwithin 120 days after the end of the fiscal year to which this Annual Report relates. Auditor Firm ID:185Auditor Name:KPMG LLPAuditor Location:Austin, TX, USA SHATTUCK LABS, INC.TABLE OF CONTENTS Part I.1Item 1. Business1Item 1A. Risk Factors31Item 1B. Unresolved Staff Comments49Item 1C. Cybersecurity49Item 2. Properties50Item 3. Legal Proceedings50Item 4. Mine Safety Disclosures50Part II.51Item 5. Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities51Item 6. Reserved51Item 7. Management’s Discussion and Analysis of Financial Condition and Results of Operations51Item 7A. Quantitative and Qualitative Disclosures About Market Risk60Item 8. Financial Statements and Supplementary Data61Item