( 於 開 曼 群 島 註 冊 成 立 之 有 限 公 司 )(Incorporated in the Cayman Islands with limited liability) Stock Code股 份 代 號 : 2 2 2 8 2024INTERIM REPORT中 期 報 告 218C.19(5)4567213435363739414268 839 22 396 PO Box 309Ugland HouseGrand CaymanKY1-1104Cayman Islands 2 3485 Maples Fund Services (Cayman) LimitedPO Box 1093Boundary HallCricket SquareGrand Cayman KY1-1102Cayman Islands 1617 2228 www.xtalpi.com 18C.19(5) 18C18C18C.03(4) 18C.03(4) * 1 20202216 2 2024630 202461318C — ••mRNA202463010121013•ß-strand12•XtalFold22,000 — •1 •10380% •90%2024LCMSMS80%95%(A*STAR)—(EDDC) •8 •(PH)(FDA)(RPDD)(PCC)2025 •FDAIND6IND •250 • •20244 •20248N1 Life(AI) •20 •AiluxAI+ •100% •XtalPi 202499 2024910 2024 2024851.3510 2024744.9 20247263(1)(2)(3)(4)(5)2024730 2024 202418C2025 34 (i)(ii) 202363080.028.3%2024630102.6 202363036.168.6%202463060.9(i)(ii)(iii) 20236 3043.94.8%202463041.8 (i)(ii)(a)(b)(c)(iii)(iv)(v) 2024630 2023630234.410.3%2024630210.4 2023630101.2131.6%2024630234.3 202363058.34.8%202463055.5 202363029.616.9%202463034.6 20236307.7447.6%202463042.4 202363099.197.2%20246302.8 202363046.930.3%202463032.72024630 2023630231.2278.7%2024630875.4 644.22023630620.3617.399.5%20246301,237.6 (i)(ii)(iii)QuantumPharm Inc. 2021Omnibus 202312311,287.462.1%20246302,087.0 2023123138.552.0%202463058.5 2023123166.126.1%202463048.8 20246302023123110,780.3 2023123139.526.7%202463028.9 2023123113.743.6%20246307.7 20231231131.327.0%202463095.820231231 2023123160.08.2%202463064.920246302.55%3.5% 2023123120246302,648.03,286.224.1% 2024630 100%20246307.8%20231231-155.3% 202463020246303,377.1202312312,827.8 2024630299.32023630299.0 2023630788.093.8%202463048.7(i)1,778.4(ii)1,148.9(i)1,951.2(ii)272.7 202363020.12024630828.1901.1 20242023630 20232024630 2023202463041.634.2 2023123120246303.01.1 202463020231231 20246302023630 20246305% 2024630760315.5 5.28187,373,0000.00001 888.2 2024630 2024630 2024630XVXV78352 (1)LS(2)20246303,406,772,761(3)81,093,362(4)QuantumPharm HoldingsTMF (Cayman) Ltd.WSH Family Holdings99%TMF (Cayman) Ltd.WSH FamilyQuantumPharmHoldings222,126,40028,105,000(5)QuantumPharm RocQuantumPharm HoldingsQuantumPharm Roc298,041,143(6)(i)Crete Helix(ii)SeveningBAlphaQuantumPharmHoldingsQuantumPharm HoldingsCrete HelixSeveningBAlphaCrete Helix122,908,500SeveningBAlpha87,814,140 (7)45,230,342 (8)Crete HelixMH International Holdings99%MH International HoldingsTMF (Cayman) Ltd.TMF(Cayman) Ltd.MH FundCrete Helix122,908,500 (9)QuantumPharm Employee Holdings59,103,125QuantumPharmEmployee HoldingsQuantumPharm Employee Benefit132021628QuantumPharm Employee Benefit (10)32,315,661 (11)SeveningBAlphaLPHappy Holding99%LPHappy HoldingTMF (Cayman) Ltd.TMF (Cayman) Ltd.LPHappy FamilySeveningBAlpha87,814,140 (12)3,800,000 (13)3,800,000 (14)2,400,000ASJX Envision LLCASJX Envision LLC40%40%20%ASJX Envision LLC 2024630XVXV78352 2024630XV23362 (1)LS(2)20246303,406,772,761(3)QuantumPharm HoldingsTMF (Cayman) Ltd.WSH Family Holdings99%TMF (Cayman) Ltd.WSH FamilyWSH Family HoldingsTMF (Cayman) Ltd.QuantumPharm Holdings(4)QuantumPharm RocQuantumPharm HoldingsQuantumPharm HoldingsQuantumPharm Roc298,041,143(5)(i)Crete Helix(ii)SeveningBAlphaQuantumPharmHoldingsQuantumPharm HoldingsCrete HelixSeveningBAlphaQuantumPharm HoldingsCrete Helix122,908,500SeveningBAlpha87,814,140(6)(7)HSG Venture VI Holdco, Ltd.HongShan Capital Venture Fund VI, L.P.HSG Venture VI Management,L.P.HSG Venture VI Management, L.P.HSG Holding LimitedSNP China Enterprises LimitedSNP China Enterprises LimitedHongShan Capital Venture Fund VI, L.P.HSG Venture VIManagement, L.P.HSG Holding Limited SNP China Enterprises LimitedHSG Venture VI Holdco, Ltd.203,444,338(8)HSG Venture VIII Holdco, Ltd.HongShan Capital Venture Fund VIII, L.P.HSG Venture VIII Management, L.P.HSG Growth VI Holdco E, Ltd.HongShan Capital Growth Fund VI, L.P.HSG Growth VI Management, L.P.HSG Venture VIII Management, L.P.HSG Growth VI Management, L.P.SNP China Enterprises LimitedHSG Holding LimitedSNP China Enterprises LimitedHSG Holding LimitedSNPChina Enterprises LimitedHSG Venture VIII Holdco, Ltd.13,303,439HSG Growth VI Holdco E,Ltd.49,076,214 (9)HCHP Holdco, Ltd.HCHP Master FundHCHP Management LimitedHCHP Management LimitedHCHP Management Holding LimitedHCHP Management Holding LimitedHCHP Holdco, Ltd.16,358,738 (10)2628601628 (11)Evolution Fund I, L.P.Evolution Special Opportunity Fund I, L.P.Evolution Fund I Co-investment, L.P.5Y Capital GP Limited5Y Capital GP Limited5Y Capital GP LimitedEvolution Fund I, L.P.Evolution Special Opportunity Fund I, L.P.Evolution Fund I Co-investment, L.P. (12) (13) 2024630XV23362 18C.14 (1)3,413,523,761 (2) (3)QuantumPharm HoldingsQuantumPharm HoldingsWSH Family Holdings99%WSH Family HoldingsTMF (Cayman) Ltd.TMF (Cayman) Ltd.WSH FamilyWSH Family (4)QuantumPharm RocQuantumPharm Roc (5)QuantumPharm RocQuantumPharmRoc2024528(i)(ii)18C.14(1) (6)Crete HelixCrete HelixMH International Hold