FORM 10-Q_________________________________________________________________ (Mark One) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June30, 2026 OR ☐TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934For the transition period from ___________to ___________Commission File Number: 001-37478_________________________________________________________________ NATERA, INC. (Exact Name of Registrant as Specified in Its Charter)_________________________________________________________________ 01-0894487 (I.R.S. Employer Identification No.) (State or Other Jurisdiction of Incorporation or Organization) 13011 McCallen PassBuilding A Suite 100Austin, TX (650) 980-9190(Registrant’s Telephone Number, Including Area Code)_________________________________________________________________ Securities registered pursuant to Section 12(b) of the Act: Common Stock, par value $0.0001 per shareNTRAThe Nasdaq Stock Market LLC (Nasdaq Global Select Market) Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filingrequirements for the past 90 days.YesNo☐ Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 ofRegulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).YesNo☐ Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or anemerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company”in Rule 12b-2 of the Exchange Act. Large accelerated filerNon-accelerated filer☐ Accelerated filer☐Smaller reporting company☐Emerging growth company☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with anynew or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.☐ Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).Yes☐No As of July31, 2026, the number of outstanding shares of the registrant’s common stock, par value $0.0001 per share, was 144,144,170. Table of Contents Natera, Inc.FORM 10-Q FOR THE QUARTER ENDED JUNE 30, 2026TABLE OF CONTENTS SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS Part I — Financial Information Item 1. Financial Statements (unaudited)Condensed Consolidated Balance Sheets at June 30, 2026 and December 31, 20255Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three and Six MonthsEnded June 30, 2026 and 20256Condensed Consolidated Statements of Stockholders’ Equity for the Three and Six Months Ended June 30,2026 and 20257Condensed Consolidated Statements of Cash Flows for the Six Months Ended June 30, 2026 and 20259Notes to Unaudited Interim Condensed Consolidated Financial Statements10Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations36Item 3. Quantitative and Qualitative Disclosures About Market Risk48Item 4. Controls and Procedures48 Item 1. Legal Proceedings49Item 1A. Risk Factors49Item 2. Unregistered Sales of Equity Securities and Use of Proceeds49Item 3. Defaults Upon Senior Securities49Item 4. Mine Safety Disclosures49Item 5. Other Information50Item 6. Exhibits51Signatures53 SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS This report contains forward-looking statements. The forward-looking statements are contained principally in the sections titled “RiskFactors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations,” but are also contained elsewhere inthis report. Forward-looking statements include information concerning our future results of operations and financial position, strategy andplans, and our expectations for future operations. Forward-looking statements include all statements that are not historical facts and, in somecases, can be identified by terms such as “believe,” “may” “will” “estimate,” “continue,” “anticipate,” “design” “intend” “expect” “could,”“plan” “potential,” “predict,” “seek,” “should,” “would” or the negative version of these words and similar expressions. These forward-looking statements include, but are not limited to, statements concerning the following: •our expectations regarding revenue, expenses and other operating results;•our expectation that, for the foreseeable future, a significant portion of our revenues wi