雅各臣科研制药二零二五/二零二六年年报

: 2633 157 258 459 660 761 116 8 117 20 35 38811232313-18 Conyers Trust Company (Cayman)LimitedCricket SquareHutchins DrivePO Box 2681Grand Cayman KY1-1111Cayman Islands 1617 jacobsonpharma@sprg.com.hk 2633 www.jacobsonpharma.com Cricket SquareHutchins DrivePO Box 2681Grand Cayman KY1-1111Cayman Islands 2324146 5 to Thrive CAR-TYikaidaAxicabtagene CiloleucelATP e-Jacob Pharma2U1,200 9 SAP • • ESG SDGs CDCC 100,000 ADHD 1,569.51,576.90.5% 300.8301.6 EBITDA 23 10 NIAS 1922 24179106725 46 7.8%65.5% DNA 4.7 Yikaida CAR-TYikaidaAxicabtagene Ciloleucel CAR-T Advanced Therapeutic ProductsATPYikaidaBDLBCLDLBCLCAR-TZUMA-7 1,200 YikaidaATPCAR-T 5.9%3.1%2.5-3.5% 100,000 CDCCCDFCPP 1,7681,749488.0473.1 1,569.57.40.5% 97%0.2 4.014.5%11.332.7% 4.5% 14.34.8%10.55.2% 10.725.8% 0.80.3%301.610.74.311.825.9 149.6135.77.8 24.218.1 825.81,268.3 98.2%99.3% 143.820.1% 100%8.3%20.8%143.8 C1 C.2.1C.2.1C.2.1 3.09D 3.13 (2)(3) (1)AB(2)(3) 3.10(2)3.21 (ii) (iii) (iv) (v) (vi) (vii) (viii) 6 1,000,0003,000,0014,000,0007,000,0018,000,00019,000,00120,000,000 3211 14.29%144.29%780 ••••••• (a) (i)(ii)(iii)(iv) (b) (i)(ii)(iii) A.2.1 (1) (2) (3) (4) 5356 I. I. II. 33 III. ••• ••••• IV. XIVA • •• 4,880,0004,880,0001,520,0001,642,000348,000348,000 58221 https://www.jacobsonpharma.com/download/Procedures.pdf F.2.2F.1.3 https://www.jacobsonpharma.comhttps://www.hkex.com.hk (a) (i) (ii) (iii) (iv) (v) (b) https://www.jacobsonpharma.com 2.07A (c) jacobsonpharma@sprg.com.hk 15 12 https://www.jacobsonpharma.comhttps://www.hkexnews.hk(i)(ii) PIC/S GMPGMP GMPPIC/S 57115 4.755.506.004.259.0015.009 117 23 1,440,249,0001,748,875,0001032459 21 ***^******** *^** 3 3.133.13 13.51B(1) 2161 (A) 63QueenshillKingshillKingshill38 2161 Cardiff UniversityThe Royal Pharmaceutical Society of Great Britain 64Jacobson Pharma Group (BVI)Limited41 2161 132195878Z Fin Limited1168182687GPI40 University of ManchesterAssociation of Chartered Certified AccountantsChartered Association of Certified Accountants 74 (B) 58The School of Pharmacy, University College London Institute of ChildHealth, University of LondonGreat Ormond Street Hospital for Children United Kingdom Department of Health Public Health Career Scientist AwardChemist andDruggists Pharmacy Practice Research MedalRoyal College of Paediatrics and Child HealthHonorary Fellowship*Royal Pharmaceutical Society*British Pharmacological Society*Facultyof Public Health, Royal Colleges of Physicians of the United KingdomFellowship Medicines Control AgencyRegulatory AuthorityDavid Lewis Centre for EpilepsyDavid Lewis CentreManchester Medical SchoolUniversity of Bradford Therakind LtdTherakind Ltd (C) 63 62TGS Global33Hodgson Impey Cheng952878 (C) 64216139 149 0011 American Express Bank Ltd.Schroders Asia Ltd. Murdoch UniversityNew York University Leonard N. Stern School of Business 6 138,000,000138,000,0006.90% 301 121% (i)(ii)(iii) 37,000,00037,000,000 3%120.5%120.1% 7,400,00013,400,000 (1) (2)21 (3) 1.43 76 (i)(ii)30% Kingshill30%30% XVXV78352347 (1)37,950,000Queenshill508,404,000Queenshill508,404,000UBS Trustees (B.V.I.) LimitedThe Kingshill TrustUBS NomineesLimitedKingshill Development Group IncTrust CoTrust CoKingshillKingshill850,684,000The Kingshill TrustThe QueenshillTrustThe Kingshill TrustThe Queenshill TrustKingshill850,684,000The Queenshill TrustTheQueenshill TrustThe Queenshill Trust8,200,000The Queenshill TrustThe Queenshill Trust8,200,000 XVXV78352347 XV23336 QueenshillQueenshill508,404,000 (2)UBS Trustees (B.V.I.) LimitedThe Kingshill TrustUBS Nominees LimitedTrust CoTrust CoKingshillKingshill850,684,000The Kingshill TrustThe Queenshill TrustUBS Trustees (B.V.I.) LimitedTrust CoKingshill850,684,000 (4)The Queenshill TrustThe Queenshill TrustThe QueenshillTrust8,200,000The Queenshill TrustTheQueenshill Trust8,200,000 (5)Longjin Investments LimitedLongjin75%Longjin157,050,000 336 衆衆218,000(i)59.92%(ii)62.39%衆A 247,000 247,000衆衆 5,580,0005,580,0004,590,000 衆5,580,000 A (I) (i)(ii)(iii) 10.0% 5,000,0006,000,0007,000,00030 6,523,0004,554,000 8,000,0009,000,00010,000,000 (II) (i)(ii)Dr. FreemanDr. Freeman 15.0%(i)(ii) (i)(ii)3,500,0003,500,0003,500,0003,000,0004,000,0005,000,00030 (II) 5,000,0006,500,000 2,142,0004,189,000100,000209,000 7,000,0008,000,0009,000,000 (III) 3,000,0003,500,0004,000,00030 582,000624,000 (i)70.25%(ii)71.62%A 0.1%5%14A.76(2)(a)A (i)(ii)(iii) 14A.56300074014A.56(1)(2)(3)(4) 29AA 55.7%53.3%51.0%48.0% 30.8%20.9%16.8%6.4% 5% 4(B) 25% 112,00093,600 57115 111(O)(ii) 183,722,000 • • • • • • • • • • •• P07324 1 (A) 1(E) (B) (C) 32 (D) 1(K) 1(J) (E) 21 1 (F) 1(R)1(S) 1(G) 1(O)(ii) 1 (G) 1(AA)1(I)1(O)(ii) 1(O)(i) 1(J) (H) 1(F)1(O)(ii)1(J) 1 (I) (i)(ii) (ii)(i) 1(O)(ii) (J) 27(E) (i) 1(X)(iii) (ii) 1(X)(iv) 1 (K) 1(N) 1(X)(v) (L)