永泰生物-B2025年度报告

24582428517173152157158160161163226 20256 25 20254 2520254 25202510 1620256 2620256 26202510 16 •88135 20256 26 183401 20254 25202510 16202510 1620254 25 255 P.O. Box 309Ugland HouseGrand Cayman KY1-1104Cayman Islands 1816 Maples Fund Services (Cayman) LimitedP.O. Box 1093, Boundary HallCricket SquareGrand Cayman, KY1-1102Cayman Islands 17 183171712-1716 118 6978 www.eaal.net 131 20207 10 19TEAL®2006EAL®EAL® EAL®EAL® EAL®6B11CAR-TTCR-T ® EAL® EAL®EAL®TCD8+TCD3 II430EAL®2025 3NDAEAL®EAL®NDA 6B11-OCIK 6B11-OCIKT6B11COC166-9OC166-96B116B11-OCIK 6B11-OCIKIII CAR-T CAR-T-19 CAR-TCAR-T-19CAR-T-19B-ALL2525CAR-T-19B(B-ALL)IND20198 202012CAR-T-19INDINDCAR-T-19I20212 25I202310III CAR-T-1925B-ALLCAR-T-19CAR-T-19 CAR-T-19II52 RC19D2CAR-T-19-D2 CAR-T-19-DNRTGF-ßBCAR-T20233 I16 aT19 aT19CD19TCD19CAR-T-19aT19CAR-TCAR-TCD19CD19CAR-TCAR-TCD19 20242aT19IINDI CAR-T-19aT19CAR-TCAR-TTCR-T TCR-T TCR-TCMVEBV CMVTCR-T-CMV20253(Pre-IND) YT007 202412 3133.813.339.3%202512 3120.5 2024123111.857.7488.7%202512 3169.5 202412 31154.221.413.9%202512 31132.8 202412 3144.53.57.9%202512 3141.0 202412 31186.444.523.9%20251231230.9 202412 31187.343.623.3%202512 31230.9 18A.08(3) EAL® EAL®EAL®TCD8+TCD3 II430 EAL®2025 3NDAEAL®EAL®NDA 6B11-OCIK 6B11-OCIKT6B11COC166-9OC166-96B116B11-OCIK 6B11-OCIKIII CAR-T CAR-T-19 CAR-TCAR-T-19CAR-T-19B-ALL2525CAR-T-19B(B-ALL)IND20198 202012CAR-T-19INDINDCAR-T-19I20212 25I202310II CAR-T-1925B-ALLCAR-T-19CAR-T-19 CAR-T-19II52 RC19D2CAR-T-19-D2 CAR-T-19-DNRTGF-ßBCAR-T20233 I16 aT19 aT19CD19TCD19CAR-T-19aT19CAR-TCAR-TCD19CD19CAR-TCAR-TCD19 20242aT19IINDI CAR-T-19aT19CAR-TCAR-TTCR-T TCR-T TCR-TTHLATCRTCRTHLATCR TCR-TCMVEBV CMVTCR-T-CMV20253(Pre-IND) YT007 18A.08(3) 27,60440,000EAL® EAL® • 20216 1712200,000 • 20212EAL®10 20225 1121,848.620 GMPGMP EAL® 2025123150 EAL® EAL® CAR-TTCR-TIII (HSCT)(SOT)(CMV)TCMVTCRCMV TCRCAR-TTCR-T GMPCAR-TCDMO 202512 31202412 31 202412 3133.839.3%202512 3120.5 b 202412 3111.8488.7%202512 3169.5 202412 3144.57.9%202512 3141.0 202412 31154.213.9%202512 31132.8 202412 317.59.3%202512 316.816 202412 312.143.0%202512 311.2 202412 31186.423.9%20251231230.9 202512 3125%202412 2202312 2015% 202412 3147.07.5202512 3154.5 202512 31103.4 20232(1)(2)Tan Zheng LtdTan Yue Yue LtdTan Zheng Ltd19,285,714Tan Yue Yue Ltd6,714,286 202512 31 20207 1011.00100,000,000 20207 3114,584,00014.58%TanZheng Ltd202511 13102,916,800202512 31617,500.80617,500,800 102.9%-2.9%202412 31102.9%-2.9% 2023 20232 20Tasly300202320234.81202320231 11Tasly68,493,150202364.425202374,452,441 2023202210 30202210 3120232 20202212 16 202322023300(a)102.3EAL®(b)197.7 2023202512 31 202512 312023300.0 2023 202412 18Tasly300202320257 152023 2026 20262 9270202630202320262 1320232026364202320262 13 2.520259 184.7847.70%(5)(1)102,916,800252.42.45202511 1320259 19202511 12202510 13 202512 31100.116.6% 202512 820.0100.0202512 3120262 10202512 31100.0202512 8 202512 315% 202512 3118356.9202470.1 202512 31 (1)(2)(a)(b)(3)202512 31202512 31 202412 310.20202512 310.35202412 310.19202512310.34 482018420198201998620046603858.SH20046201312013120158JY Research Holdings LimitedJY Research Holdings LimitedHamiyangHamiyang2015920201220234668120237 62198320074020011020238600535.SH19962001 4520042012202020201620142016 712003222003300109.SZ 442003720067200682010820255 5220007200972020008200312003131 4320052005600062 642020620206 29198371988719973302002920196300016.SZ202011430047.BJ 532020620206 2919971120031200662220011020061020172202510 1495120101220227143020175202362333 472020620206 2920026201082019252002720051220124201312201412016420167 4520026202002720216 5520199519981998200520052016120138201612016220182 20247 2620 202512 31 20256 25 20256 2620256 26202510 1620254 2520254 25202510 16 20256 26 2427 19T2006 622388(2) EAL® 202512 31 2427 7172 1213 3.25C1 1213 202512 31 XVXV78352 (1)LXV 5,395,000 Tan Zheng LtdTan Zheng Ltd158,890,428120,490,428Tan Zheng LtdTan Zheng LtdTan Zheng Ltd158,890,428 XVXV78352 XV23336 (1)LXVSXV617,500,800(2)20198 29Tan Zheng Ltd(3)(BVI)53.39%(BVI)(4)Poly PlatinumPoly Platinum(GP)(GP)Poly Platinum(5)59,794,28646,080,000Tan Xiao Yang Ltd13,714,286TanXiao Yang LtdTan Xiao Yang LtdTan Yueyue LtdTan Yueyue Ltd6,714,286Tan Xiao Yang LtdTan Zheng Ltd(6)44,167,65642,579,713Zhang Jun Zheng Ltd1,587,543Zhang Jun Zheng LtdZhang Jun Zheng LtdZhang Jun Zheng LtdTan Zheng Ltd(7)102,880,787Jiaze Global Capital Limited202620262.92Jiaze GlobalCapital Limited16.66%20262 920262 13Jiaze Global Capital Limited94.78%50.1%49.9% XV23336 2019123120206 6 1.00 7 5.5 201912 31103.5 1.2. 9,872,8501.60% a)()30.00% b)()10.00%10.00%50,000,0008.10% c)(a)(d)10.00% d)(a)(c)(c) 1.00% (1)0.10%(2)5.0 10 (i)(ii)(iii) 20206 6104 50,000,000 202512 31(1)(2)(3)(4)(5) (i)(ii)CROSMO202512 3144.8%202450.2%202512 3122.9%202419.9% 5% 37 16 39 202512 311,631,922,00020241,402,498,000 202512 31 36A