Imunon Inc美股招股说明书(2026-03-23版)

Prospectus Supplement dated September 3, 2024, andProspectus Supplement dated July 22, 2025) IMUNON, INC. Up to $17,000,000 of Common Stock This prospectus supplement amends and supplements the information in the prospectus supplement, dated September 3, 2024, asamended and supplemented by the prospectus supplement dated July 22, 2025 (as amended and supplemented, the “ATM ProspectusSupplement”), to the accompanying base prospectus, dated May 22, 2024 (the “Base Prospectus” and, collectively with the ATMProspectus Supplement, the “Prospectus”) filed as part of our registration statement on Form S-3 (File No. 333-279425) (the“Registration Statement”), relating to the offer, issuance and sale of shares of our common stock, par value $0.01 per share (“CommonStock”), from time to time pursuant to the terms of an At the Market Offering Agreement, dated as of May 25, 2022, as amended byAmendment No. 1 to At the Market Offering Agreement, dated as of May 15, 2024 (as amended, the “Sales Agreement”), by andbetween us and H.C. Wainwright & Co., LLC, as sales agent or principal (“Wainwright” or the “sales agent”). Through the date hereof,we have sold an aggregate of $4,797,848 of shares of our Common Stock through the sales agent under the Sales Agreement. Thisprospectus supplement should be read in conjunction with the Prospectus, and is qualified by reference thereto, except to the extentthat the information herein amends or supersedes the information contained in the Prospectus. This prospectus supplement is notcomplete without, and may only be delivered or utilized in connection with, the Prospectus, and any future amendments orsupplements thereto. We are filing this prospectus supplement to amend and supplement the Prospectus to increase the aggregate amount we intend to sellpursuant to the Sales Agreement. As of the date of this prospectus supplement, we are offering up to an aggregate of $17,000,000 ofour Common Stock for sale under the Sales Agreement, consisting of $10,000,000 that was previously authorized pursuant to the ATMProspectus Supplement and an additional $7,000,000 pursuant to this prospectus supplement. Our Common Stock is listed on The Nasdaq Stock Market LLC under the symbol “IMNN.” On March 19, 2026, the last reported saleprice for our Common Stock on Nasdaq was $2.95 per share. The validity of the shares being offered hereby will be passed upon by Thompson Hine LLP. Investing in our securities involves a high degree of risk. Before making an investment decision, please read “Risk Factors”beginning on page S-3 of the ATM Prospectus Supplement dated September 3, 2024 and the other documents and informationcontained or incorporated by reference in this prospectus supplement and the ATM Prospectus Supplement. Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of thesesecurities or determined if this prospectus supplement is truthful or complete. Any representation to the contrary is a criminaloffense. H.C. Wainwright & Co. The date of this prospectus supplement is March 23, 2026