实现循证决策研究的共同愿景

BastienKolt,aTanjaKuchenmüller,aAhmedMandil,bAnnetteBoaz,cDanielFPatiño-Lugo,dJohnCReeder,aKathrynOliver,eRobertFTerry,fSarahCCharnaud,aTarangSharmaa& TikkiElkaPangestug this commitment, consolidated with thenetwork’s 2021 call for action to enhanceevidence-informed policy-making.4Today, the network supports the insti-tutionalization of evidence use in healthpolicy-making in more than 50 countries.A growing body of research on The World Health Organization (WHO)defines knowledge translation as theexchange, synthesis and effective com-munication of reliable and relevantresearch results.1Also known as researchutilization or knowledge mobilization,knowledge translation is a transdisci-plinary process that promotes sustainedinteraction between researchers andusers, tailoring information so thatevidence-informed policy-making in-terventions are more widely adopted.1Despite considerable progress in consensus on the most effective meth-ods for translating knowledge intopolicy across different contexts and set-tings. Knowledge translation researchis fragmented and insufficiently coor-dinated within and across disciplines,sectors and countries.8Expertise andfunding in this field are often narrowlyfocused on specific priorities linked tofunding agencies’ interests, resulting inmissed opportunities for collaborationand in research waste.9With the vastamount of research in progress, iden-tifying true research gaps and priori-tizing knowledge translation domainsis challenging. Many of the efforts inprioritizing research in knowledgetranslation either target particularcontexts or localities, or concentrate onspecific sectors or institutions, resultingin further fragmentation.10Moreover,they often focus on the relationshipsbetween evidence producers and users,neglecting the role and needs of otherinterest-holders, such as knowledgebrokers, funders or educators. Glob-ally coordinated knowledge translationresearch priorities are also absent in theliterature, and knowledge translationresearch is disproportionately concen-trated in high-income countries.8To address these challenges, we saw knowledge translation examines themethods, mechanisms and measure-ments that shape how evidence is pro-duced, disseminated, used and can bepromoted in policy-making.5Much is al-ready known about what works, includ-ing establishing relationships betweenresearchers and policy-makers; timelyaccess to high-quality and relevant re-search evidence; and capacity-buildingin evidence-informed policy-makingfor policy-makers.6Using these lessons,along with systematic approaches andtrusted partnerships, the network con-tinues to promote the use of evidencefor policy impact. For example, in Brazil,the network implemented a knowledgetranslation intervention, producing apolicy brief and policy dialogues. Theintervention led to new policy strategiesthat contributed to a rapid decline inperinatal mortality, demonstrating thetangible impact of evidence use and thenetwork’s methods on health outcomes.7Yet, despite widespread implemen- knowledge translation and evidence-informed policy-making, translatingevidence into policy and practiceremains challenging, mainly due toinsufficient institutional capacities andfinancial and human resources.2Yetwith the emergence of competing nar-ratives and misinformation, the need forevidence-informed policy has becomeincreasingly critical.The concepts of knowledge trans- lation and evidence-informed policy-making emerged in the 1980s from theevidence-based medicine movement,which sought to close the persistent gapbetween research and policy.2WHO hasplayed a central role in advancing theseapproaches. In 2005, WHO reformedits guideline production process, andthe World Health Assembly adopted aresolution calling on Member States tostrengthen the knowledge base for deci-sion-making and establish mechanismsto support evidence-based policies.3Inresponse, WHO launched the Evidence-informed Policy Network, which hasbecome a flagship initiative for advanc-ing evidence-informed policy-makingglobally. The coronavirus disease 2019(COVID-19) pandemic further reinforced tation, evidence on the effectiveness ofknowledge translation interventions forpolicy-makers and on how they influ-ence decisions remains limited. Persis-tent gaps remain in areas such as insti-tutionalization of evidence-informedpolicy-making, raising awareness andco-creating policy-relevant evidenceamong producers, intermediaries andusers.8Knowledge translation researchfaces numerous challenges, with little a strategic role for WHO in conveningevidence producers, users, intermediar-ies and funders to collaboratively setresearch priorities and catalyse invest-ments to reduce research waste. WHOidentified the importance of a multidis-ciplinary research agenda that addresseskey gaps in how evidence informs policyand practice. This effort must be globaland equitable to break silos, enhanceresearch coordination, bridge disciplin- ary divides and enrich the current bo