Destiny Tech100 Inc美股招股说明书(2025-11-05版)

Maximum Offering of up to $1,000,000,000Common Stock Supplement No. 2 dated November 5, 2025to theProspectus and Statement of Additional Information dated August 8, 2025 This prospectus supplement modifies, amends and supplements certain information contained in the Prospectus of DestinyTech100 Inc. (the “Company”) dated August 8, 2025, as amended or supplemented (the “Prospectus”) and the statement of additionalinformation, dated August 8, 2025, as amended or supplemented (the “Statement of Additional Information”), which relate to the saleof shares of the Company’s common stock pursuant to the “at-the-market offering” with Jefferies LLC. Capitalized terms used in thisprospectus supplement and not otherwise defined have the meaning specified in the Prospectus and/or Statement of AdditionalInformation. You should carefully consider the "Risk Factors" section beginning on page 26 of the Prospectus. Net Asset Value In connection with our regular net asset value determination process, as provided in our valuation policies and procedures, ournet asset valueas of September 30, 2025, is $11.37 per share of our common stock. Portfolio The following table sets forth certain information as of September 30, 2025, for each portfolio company in which we haveinvested. Percentage of portfolio column is based on an approximate portfolio value of $153.3million as of September 30, 2025. (1) The Company has a direct investment in a Special Purpose Vehicle ("SPV") which has invested in an underlying portfoliocompany. If applicable, the number of units presented, are the units in the SPV owned by the Company, which represents theequivalent number of securities of the underlying portfolio company for which the investment has economic exposure. (2) The Company has a direct investment in an SPV which has economic exposure to an underlying portfolio company. Thenumber of units presented, if applicable, are the units in the SPV owned by the Company, which represents the equivalent number ofsecurities of the underlying portfolio company for which the investment has economic exposure. The SPV has invested through one ormore underlying SPVs. (3) During the year ended December 31, 2024, the SPV disposed of the underlying asset. As of June 30, 2025, the SPV doesnot hold any underlying assets. (4) The SPV has invested through one underlying SPV, resulting in the related economic exposure to the Company. (5) The SPV has invested through five underlying SPVs, resulting in the related economic exposure to the Company. Five ofthe underlying SPVs have one additional layer of SPVs, while one has two layers. *Values may not sum due to rounding. (6) Investment is an SPV that holds multiple forward agreements that represent common shares of the indicated portfoliocompany. Forward contracts involve the future delivery of shares of a portfolio company upon such securities becoming freelytransferable or the removal of restrictions on transfer. The aggregate total of the forward contracts for each SPV represents less than5% of the Company’s net assets. The counterparties to the forward contracts are the shareholders of the private company who own therestricted shares. The Company does not have information as to the identities of the specific counterparties (the shareholders of theprivate company);however, counterparty risk is mitigated by the fact that there is not a single counterparty on the opposite side of theforward contracts and the sole obligation of the counterparties is to transfer shares following such time as the shares become freelytransferable. At-the-Market Offering From August 8, 2025, the date the Company entered into an Open Market Sale AgreementSM(the “Sales Agreement”) withJefferies LLC (the “Sales Agent”) through September 30, 2025, we sold a total of 2,974,547 shares of common stock at a weightedaverage price of $26.75 per share under the Sales Agreement (the “At-the-Market Offering”). The net proceeds as a result of thesesales of common stock were approximately $79,444,023 after deducting commissions and fees.