科笛-B2025年中期报告

18 36 37 38 40 41 43 58 (ACG, HKACG)20258 28(FCG, HKFCG)20258 28 97927 20258 2820258 28 183401 20258 2820258 28 13662805 20258 2820258 2820258 2820258 28 (ACG, HKACG)2025828(FCG, HKFCG)2025828 科笛集團 1617 Harneys Fiduciary (Cayman) Limited4th Floor, Harbour Place103 South Church StreetP.O. Box 10240Grand Cayman KY1-1002Cayman Islands 56 43620 1-102 131 Harneys Fiduciary (Cayman) Limited4th Floor, Harbour Place103 South Church StreetP.O. Box 10240Grand Cayman KY1-1002Cayman Islands 02487 www.cutiatx.com 3 2019 CATAME® 4 CU-102014%CU-40102CU-40102CU-30101 CU-40102 CU-40102II5α-CU-40102CU-401022025620258CU-40102CU-40102IIIICU-40102 CU-102014% CU-10201CU-10201 CU-10201202411CU-10201 CU-10201IIICU-10201 5 CU-10101 CU-10101CU-10101CU-10101IND20245CDE20249I CU-30101 CU-30101CU-30101CU-3010120241III20247CU-30101IIICU-30101Pliaglis® CU-20401 CU-20401CU-20401CU-20401 CU-20401202412CU-20401II2028IICU-20401CU-20401CU-20401CU-20401 科笛集團 CU-40102202568CU-40102CU-102014%202411 7 GMP2023GMPFDA 20244 20258CU-40102CU-40102CU-40102CU-40102 20258288.4028,904,00020259528,904,0009.05%8.30%8.40242.79240.27(i)45%108.12(ii)45%108.12CU-40102CU-102014%(iii)10%24.032025828202595 科笛集團 2025CU-102014%CU-40102CU-30101 CU-20401IIIICU-20401III CATAME® 9 202463095.630.6%202563066.3CU-40102CU-102014% 202563034.2202463045.224.3% 202563032.1202463050.336.3%2024630202563053%48% (i)(ii)(iii)202463011.910.7%202563010.6 202463011.858.9%20256304.9 2024630103.511.4%202563091.7CU-40102CU-10201 科笛集團 202563078.9202499.020.3%(i)(ii) 202463067.65.0%202563064.2 11 20256307.22024630 (i)(ii)(iii)(iv)202463020256300.0340.0 20246304.82.1%20256305.0 20256302024630 2025630239.42024630200.919.1% 科笛集團 (i)(ii) 2025630208.820241231385.745.9% 13 202563010.72024123110.51.5% 2025630462.020241231480.03.7% 2025630822.5208.8260.0196.3 202563016 2025630 202563032.2%2024123130.0%100% 科笛集團 20236131663,840,0002023828 20256305% 2025630 2025630 20256304.8202412315.0 202563020241231 202563020241231 15 2025630 2025630298202563090.62024630113.72025630 科笛集團 392.7356.82025630 2025630571XV(i)XV78(ii)352(iii) 2025630XVXV78352 18 科笛集團 2025630XV23336 19 1.6 Dimensions LP6 Dimensions Affiliates Fund, L.P.6 Dimensions Affiliates6Dimensions Capital GP, LLC6 Dimensions Capital GP, LLC6 Dimensions LP6Dimensions Affiliates 2. 3.AuroraCutis Limited54,019,020Aurora Cutis LimitedFutu Trustee LimitedFutu Trustee LimitedAurora CutisIIAurora Cutis LimitedIFutuTrustee LimitedAuroraCutis Limited2025630376,100I 科笛集團 4.YF Dermatology LimitedYunfeng LPYunfeng LPYunfeng GPYunfeng GPYunfeng LPYunfeng GPYF Dermatology Limited 5.HSGGrowthHongShanGrowth Fund VHongShanGrowth Fund VHSGManagementHSGManagementHSGHolding LimitedHSGHolding LimitedSNPChinaEnterprisesLimitedSNP China Enterprises LimitedHongShan Growth Fund VHSG ManagementHSG Holding Limited SNP China Enterprises LimitedHSG Growth 6. 2025630336 20241,362,60015.10.44714%20256301,362,600 2025630 13.2013.2113.22 2025630 21 2025630202563020256300% 2019823 1. (a) (b) (c) 70,685,670 52,197,77416.3% (d) (e) Aurora Cutis LimitedFutu Trustee LimitedFutuTrustee LimitedI20211025I54,019,020Aurora Cutis LimitedII2025630376,100I AuroraCutisIIIIFutuTrustee Limited2023121FutuTrustee LimitedII8,572,580IIII III 6,786,920 (f) (1)(2) (g) 1020198234 23 (a) (b) (i)(ii)(iii)100%(iii)10%110% 100% (c) 10(a)(b)(c) (d) (a) (b) (c) 20251120236122025630 2025630 (i)21,830,40020256306.8%(ii)13,216,94020256304.1%(iii)8,613,46020256302.7% (i)(ii)(iii)(iv) 20%48 (2) (3)9.91 20251120236122025630 2025630 (i)29,690,52920256309.3%(ii)15,138,29920256304.7%(iii)14,552,23020256304.6% (i)(ii)(iii) 28 (1)25%202211325%(2)(3)0.00002(4)9.914.44 2. 2023530 (a) (b) (a)(b) (c) (i)(iv)(v)10%30,402,446202511202563030,402,4469.5% (ii)(i)1%3,040,24420251120256303,040,2440.95% (iii)(iv)(1)(2)13.39(6)13.39(7)13.40 13.4113.4213.36(2)(a)(1)(2) (iv)10% 31 (v)(iv) (d) 121% (e) (i) (ii) (iii) (f) (g) 121012 (h) 10 2025630202563030,402,446 (i) 1020235308 2025630 (1)202549686(2)20251147720258(3)202546178(4)20258(5)20258(6)20258 13.51B(1) 33 20258283.28 34 科笛集團 20258282025828 2025630 2025630 20256302024630 202361220256302410 Cutia Therapeutics科笛集團 2025828 35 Tel+852 2846 9888Fax+852 2868 4432ey.com Ernst & Young27/F, One Taikoo Place97927 979 King’s RoadErnst & Young27/F, One Taikoo Place979 King’s RoadQuarry Bay, Hong Kong Cutia Therapeutics 3757CutiaTherapeutics2025630343434 2410 34 2025828 2025630 20256 30 39 2025630 40 2025630 42 20256 30 1. 1.1 CutiaTherapeutics201951520236124thFloor,Harbour Place, 103 South Church Street, P.O. Box 10240, Grand Cayman KY1-1002, CaymanIslands 1.2 20256303420241231 2 20241231 21 21 3. 8 2025202463010% AB 4. 5. 6. 科笛集團 7. 8. 9. 20256302024630 10. 20252024630 20252024630 10. 11. 20256304,635,000202463012,665,000 2025630974,00020246306,000 13.