实现全民免疫覆盖的进展和挑战

DTP immunizationcoverage and the numberof unimmunized childrenimproved slightly in 2024Programme performance in the first year of life,as measured by DTP-containing vaccinecoverage, is slightly better than in 2023 whileremaining below the pre-pandemic 2019baseline.There are 171k fewer Zero Dose Children (ZDC)and 426k fewer un-and-under vaccinated in2024 compared to 2023.WUENIC 20242 Measles immunizationcoverage and the numberof unimmunized childrenimproved more clearly in2024Measles vaccine coverage improved moreclearly. There were 1.7m fewer measles ZeroDose children than in 2023. This outperformanceof Measles over DTP vaccine is explained byDTP-specific issues such as stock-outs incountries like the Philippines, Sudan, andIndonesia, as well as stronger measlesperformance in Nigeria, Brazil, and Pakistan.No additional countries reported MCV2 in 2024,but countries that recently introduced a seconddose continue to increase coverage.WUENIC 20243 Top 10 countries with themost unvaccinatedchildren and lowestDTP1coverage in 2024The list of countries with most zero-dosechildren contains the same countries in 2024 asin 2023, although the order changed with Sudancontinuing to worsen under conflict. It is now thelowest performing country in the world.Gabon, Bolivia, and Azerbaijan entered the list often worst performing countries by DTP1coverage.WUENIC 20244 Top 10 countries with themost unvaccinatedchildren and lowestMCV1coverage in 2024The list of countries with most measles zero-dose children contains the same countries in2024 as in 2023, although the order changedwith Sudan continuing to worsen under conflict.Benin, Papua New Guinea, and EquatorialGuinea entered the list of ten worst performingcountries by MCV1 coverage.WUENIC 20245 The improvement in 2024 isstill insufficient to restoreperformance to the 2019baseline, or to strengthen ittowards 2030 objectivesThe Immunization Agenda 2030 (IA2030) aims toleave no one behind with immunization and calls onall countries to reduce the number of zero dosechildren by half by 2030.This chart shows the estimated number of zero-dose children in 2000-2024 (dark blue bars), thezero-dose target by 2030 (light blue bar), and theannual goals to reach the 2030 target based on alinear trajectory (points).In 2024, the number of zero-dose children was still1.4m above the 2019 number, and approximately 4mabove the trajectory that would be needed toachieve the IA2030 goal of halving the number ofzero-dose children between 2019 and 2030.WUENIC 20246 35 countries with a Gavi funded Big Catch-Up planhave committed to vaccinate older children whomissed their vaccination during the pandemic and atthe same time to restore and strengthen routineimmunization for infants. 16 of these have alsomanaged to strengthen routine immunization above2019 levels, while 16 others have not.Definitions: Countries are deemed to have not recovered frompandemic disruptions if the 2024 achievement is still below the2019-2023 range. They have partially recovered if the 2024achievement is better than the preceding 4 years, but still below the2019 baseline. They have strengthened if their 2024 performance isbetter than in 2019. Countries with high and stable coverage above90% are depicted separately. Green labels indicate which countriesimproved classifications compared to the 2024 report.WUENIC 202416 countries with a "BigCatch-Up" plan supportedby Gavi have strengthenedtheir performance above2019 baselines7 DTP3 coverage by WHOregionAMR and SEAR are performing better than in 2019for DTP3 coverage, while AFR has fully recoveredto that level. EMR has lost ground as conflictdisrupted immunization programmes in Sudanand Yemen.WUENIC 20248 DTP3 coverage distributionby WHO regionThis chart shows the distribution of coverageamong countries by WHO region. The weightedmean in the previous slide is affected by outliersand by changes in populous countries. The medianand inter-quartile range shown here is morereflective of the trend in the bulk of countries.Higher medians and smaller IQR reflects broadlybetter performance and greater equity.Unlike the weighted mean coverage shown in theprevious slide, the median DTP3 countryperformance was worse in 2024 compared to 2019in AFR, AMR, EUR and WPR. It has improved in EMR,highlighting how the lowered coverage in thatregion is driven by populous conflict affectedcountries. The median country in AFR, SEAR andWPR do noticeably better now than in 2000.Data do not suggest sustained improvements inequity over recent years, though is better than in2000 in AFR and SEAR.WUENIC 20249 MCV1 coverage by WHOregionFor measles, regional coverage trends aresimilar to DTP3, although WPR is doing a bitworse, and EMR a bit better in comparison.WUENIC 202410 MCV1 coverage distributionby WHO regionConsidering the distribution of coverage incountries by WHO region, rather than theweighted mean coverage, the median MCV1country performance was worse in 2024compared to 2019 in AMR and EUR, bu