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$500,000,000 4.30% Senior Notes due 2028$750,000,000 4.60% Senior Notes due 2031$750,000,000 5.20% Senior Notes due 2036Unconditionally Guaranteed byEnterprise Products Partners L.P. This prospectus supplement relates to our offering of three series of senior notes. The senior notes due 2028, which we refer to as “2028 notes,” will bear interestat the rate of 4.30% per year and will mature on June 20, 2028. The senior notes due 2031, which we refer to as “2031 notes,” will bear interest at the rate of 4.60% peryear and will mature on January 15, 2031. The senior notes due 2036, which we refer to as “2036 notes,” will bear interest at the rate of 5.20% per year and will matureon January 15, 2036. We refer to the 2028 notes, the 2031 notes and the 2036 notes, collectively, as the “notes.” We will pay interest on the 2028 notes on June 20 and December 20 of each year, beginning on December 20, 2025. We will pay interest on the 2031 notes onJanuary 15 and July 15 of each year, beginning on January 15, 2026. We will pay interest on the 2036 notes on January 15 and July 15 of each year, beginning on January15, 2026. We may redeem some or all of the notes of each series at any time at the applicable redemption prices described in “Description of the Notes—OptionalRedemption,” plus accrued and unpaid interest thereon to the redemption date. The notes will be unsecured and will rank equally with all of our other existing and future unsecured and unsubordinated indebtedness. The notes will beguaranteed by our parent, Enterprise Products Partners L.P., on an unsecured and unsubordinated basis, and in certain circumstances may be guaranteed in the future onthe same basis by one or more of our subsidiaries. The notes will not be listed on any securities exchange. Investing in the notes involves certain risks. See “Risk Factors” beginning onpageS-7of this prospectussupplement and on page 2 of the accompanying prospectus. Neither the United States Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities ordetermined if this prospectus supplement or the accompanying prospectus is truthful or complete. Any representation to the contrary is a criminal offense. (1)Plus accrued interest, in the case of the 2028notes, from June 20, 2025, if settlement occurs after that date.(2)Plus accrued interest, in the case of the 2031notes, from June 20, 2025, if settlement occurs after that date.(3)Plus accrued interest, in the case of the 2036 notes, from June 20, 2025, if settlement occurs after that date. The underwriters expect to deliver the notes in book-entry form only, through the facilities of The Depository Trust Company, against payment on or about June20, 2025. Joint Book-Running Managers TDSecurities PNCCapitalMarketsLLCSOCIETEGENERALEUSBancorp J.P.MorganSMBCNikko TABLE OF CONTENTS Prospectus Supplement SummaryRisk FactorsUse of ProceedsCapitalizationDescription of the NotesMaterial U.S. Federal Income Tax ConsequencesCertain ERISA ConsiderationsUnderwritingLegal MattersExpertsInformation Incorporated By ReferenceForward-Looking Statements Prospectus About this ProspectusOur CompanyRisk FactorsUse of ProceedsDescription of Debt SecuritiesDescription of our Common UnitsCash Distribution PolicyDescription of our Partnership AgreementMaterial Tax ConsequencesInvestment in Common Units or Debt Securities by Employee Benefit PlansPlan of DistributionWhere You Can Find More InformationIncorporation by ReferenceForward-Looking StatementsLegal MattersExperts Important Notice About Information in ThisProspectus Supplement and the Accompanying Prospectus This document is in two parts. The first part is this prospectus supplement, which describes the terms of this offering of notes and certain terms ofthe notes and the guarantee. The second part is the accompanying prospectus, which describes certain terms of the Indenture (as defined under“Description of the Notes”) under which the notes will be issued and which gives more general information, some of which may not apply to thisoffering of notes. If the information varies between this prospectus supplement and the accompanying prospectus, you should rely on the information in thisprospectus supplement. You should rely only on the information contained or incorporated by reference in this prospectus supplement and the accompanyingprospectus or any free writing prospectus prepared by or on behalf of us. We have not, and the underwriters have not, authorized anyone toprovide you with additional or different information. If anyone provides you with additional or different information, you should not rely on it.We are not, and the underwriters are not, making an offer to sell these securities in any jurisdiction where the offer is not permitted. You shouldnot assume that the information contained in this prospectus supplement or the accompanying prospectus is accurate as of any date other thanthe date on the




