三项急性研究的统一研究评审表：测试指南429、437和491

OECD Series on Pesticides and Biocides Harmonised Study Review Forms for threeacute studies: Test Guidelines 429, 437 and491 Pleasecitethispublicationas: OECD (2024),Harmonised Study Review Forms for three acute studies: TestGuidelines 429, 437 and 491, OECD Series onPesticides and Biocides, OECD Publishing, Paris,https://doi.org/10.1787/19d63ef7-en. © OECD 2024 Attribution 4.0 International (CC BY 4.0) This work is made available under the Creative Commons Attribution 4.0 International licence. By using this work, you accept to be bound by the terms of this licence (https://creativecommons.org/licenses/by/4.0/). Attribution–you must cite the work. Translations–you must cite the original work, identify changes to the original and add the following text:In the event of any discrepancy between the original work and thetranslation, only the text of original work should be considered valid. Adaptations–you must cite the original work and add the following text:This is an adaptation of an original work by the OECD. The opinions expressed and arguments employedin this adaptation should not be reported as representing the official views of the OECD or of its Member countries. Third-party material–the licence does not apply to third-party material in the work. If using such material, you are responsible for obtaining permission from the third party andfor any claims of infringement. About the OECD TheOrganisation for Economic Co-operation and Development(OECD)is an intergovernmentalorganisation in which representatives of 38 countries in North and South America, Europe and the Asiaand Pacific region, as well as the European Union, meet to co-ordinate and harmonise policies, discussissues of mutual concern, and work together to respond to international problems. Most of the OECD’swork is carried out by more than 200 specialised committees and working groups composed of membercountrydelegates.Observers from several Partner countries and from interested internationalorganisations attend many of the OECD’s workshops and other meetings. Committees and working groupsare served by the OECD Secretariat, located in Paris, France, which is organisedinto directorates anddivisions. TheEnvironment, Health and Safety Division publishes free-of-charge documents in twelve differentseries:Testing and Assessment;Good Laboratory Practice and Compliance Monitoring;Pesticides;Biocides;Risk Management;Harmonisation of Regulatory Oversight in Biotechnology;Safety ofNovel Foods and Feeds; Chemical Accidents; Pollutant Release and Transfer Registers; EmissionScenario Documents; Safety of Manufactured Nanomaterials;andAdverse Outcome Pathways.More information about the Environment, Healthand Safety Programme and EHS publications is availableon the OECD’s World Wide Web site (https://www.oecd.org/en/topics/chemical-safety-and-biosafety.html). This publication was developed in the IOMC context. The contents do not necessarilyreflect the views or stated policies of individual IOMC Participating Organizations. The Inter-Organisation Programme for the Sound Management of Chemicals (IOMC)was established in 1995 following recommendations made by the 1992 UN Conferenceon Environment and Development to strengthen co-operation and increase internationalco-ordination in the field of chemical safety. The Participating Organisations are FAO,ILO,UNDP,UNEP,UNIDO,UNITAR,WHO,World Bank,Basel,Rotterdam andStockholm Conventions and OECD. The purpose of the IOMC is to promote co-ordinationof the policies and activities pursued by the Participating Organisations, jointly orseparately, to achieve the sound management of chemicals in relation to human healthand the environment. Foreword This document provides the second set of outputs of the Review Sharing initiative which theWorking Party on Biocides (WPB) has undertaken over the last few years. Review sharing wasproposed to leverage constrained specialist resourcesmore efficientlyand permit thosespecialists (generally toxicologists) to pursue more value-added activities such as risk orexposure assessment. An expert group of the WPB was formed which defined a process and created the necessarydocuments to realize the objectives of the project. The expert group reviewed available national checklists and processes to draft and refineHarmonized Standard Review Forms for the studies in scope and develop a Standard OperatingProcedure for applicants and government reviewers to follow. The Standard Operating Procedureand HSRF for the acute studies commonlyknown as the “6 Pack” acute studies were initiallypublished as “Sharing of Government Biocides Reviews: Standard Operating Procedure andHarmonised Study Review Forms of the "6 pack" Acute Studies”, in the Series on Biocides (No.14) in February 2019. The Standard Operating Procedure described in the Series on Biocides (No. 14) applies to thenew HSRF described in the current publication. The studies included in this document are the HSRF for the fol