Metagenomi Inc 2024年度报告

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15(d) of the Act. Yes☐No☒ Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes☒No☐ (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes☒No☐ Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growthcompany. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act. Large accelerated filer☐Accelerated filer☐Non-accelerated filer☒Smaller reporting company☒Emerging growth company☒ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financialaccounting standards provided pursuant to Section 13(a) of the Exchange Act.☒ If securities are registered pursuant to Section 12(b) of the Act, indicate by check mark whether the financial statements of the registrant included in the filing reflect thecorrection of an error to previously issued financial statements.☐ Indicate by check mark whether any of those error corrections are restatements that required a recovery analysis of incentive-based compensation received by any of theregistrant’s executive officers during the relevant recovery period pursuant to §240.10D-1(b).☐ Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes☐No☒ The aggregate market value of the voting and non-voting common equity held by non-affiliates, based on the closing price of the shares of common stock on The Nasdaq GlobalSelect Market on June 28, 2024 (the last business day of the registrant’s most recently completed second fiscal quarter), was $127,036,500. This calculation does not reflect adetermination that certain persons are affiliates of the registrant for any other purpose. The number of shares of registrant’s Common Stock outstanding as of March 7, 2025 was 37,383,472. Table of Contents PART IItem 1. Business.......................................................................................................................................................................4Item 1A.Risk Factors.................................................................................................................................................................34Item 1B.Unresolved Staff Comments .......................................................................................................................................88Item 1C.Cybersecurity...............................................................................................................................................................88Item 2.Properties.....................................................................................................................................................................88Item 3.Legal Proceedings .......................................................................................................................................................88Item 4.Mine Safety Disclosures..............................................................................................................................................89 PART IIItem 5. Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities .90Item 6.[Reserved] ...................................................................................................................................................................90Item 7.Management’s Discussion and Analysis of Financial Condition and Results of Operations .....................................91Item 7A.Quantitative and Qualitative Disclosures About Market Risk ....................................................................................101Item 8.Financial Statements and Supplementary Data ...........................................................................................................101Item 9.Changes in and Disagreements With Accountants on Accounting and Financial Disclosure ....................................101Item 9A.Controls and Procedures..............................................................................................................................................101Item 9B.Other Information.................................................................................................................