腾盛博药-B：2024年度报告

Brii Biosciences Limited騰盛博藥生物科技有限公司 ()於開曼群島註冊成立的有限公司 股份代號 :2137 2024年度報告 Zhi HONG Martin J MURPHY JRGrace Hui TANG Gregg Huber ALTON Grace Hui TANG Martin J MURPHY JRGrace Hui TANG Gregg Huber ALTONZhi HONGMartin J MURPHY JR PO Box 309, Ugland HouseGrand Cayman KY1-1104Cayman Islands Gregg Huber ALTON WeWork One City CenterSuite 05-130, 110 N Corcoran StDurham, NC 27701United States of America First Citizens BankGoldman Sachs International BankJ.P. Morgan Chase Bank 33 191920 2137 (1)2騰盛博藥 •ENSUREElebsiran + PEG-IFNαvs PEG-IFNα•ENRICHBRII-179elebsiran + PEG-IFNα•ENHANCEBRII-179 + elebsiran + PEG-IFNα(2)ElebsiranBRII-835VIR-2218(3)TobevibartBRII-877VIR-34342Vir Biotechnology(4)EpetraboroleBRII-658AN2(5) ZhiHONG6120183220213242018223202291202171320229120217132022930 Hong20181BriiBiosciences,Inc20192 752021622202171320217132021713202291 51720042543200711255220189ATACreativityGlobalAACG20081MLCO200612200083492010122120064 2003112017220014200611200112200412200172002619941199722000820003200081989119805198812CLP Power Cantrell19915(WestminsterCollege)19985(University of Missouri-Columbia) Neuendorff199752010620157(SPHR,SHRM-SCP)20126(GPHR)20115(PHR-CA) 562022101202071620229302018422020715 202171326.142023324 b)202412VBIVaccines,Inc.VBIK2VBIEquity Trust, LLCK2 HealthVentures LLCBRII-179BRII-179BRII-179BRII-179VBI1.2BRII-179 2024123140.0%202347.0%11.6%202322.0% 20241231 Zhi Hong Robert Taylor Nelsen2024713 16.19Gregg Huber Alton 2.ZhiHong41,431,315(i)282,190(ii)20236,928,000(iii)20231,188,125(iv) JINGFAN HUANG 2020JINGFAN HUANGUA DTD9/24/2020Zhi Hong 202017,033,000(v)Hong202016,000,000 3.7,436,500(i)1,442,957(ii)3,066,668(iii)20231,996,500(iv)2023930,375 ARCHVenturePartnersIX,LLCRobertTaylorNelsenClintonBybeeKeith CrandellARCH Venture Fund IX, L.P.ARCH Venture Fund IX Overage, L.P. 3.BoomingPassionLimited72,019,612BoomingPassionLimitedBoyuCapitalFundIII,L.P.BoyuCapitalFundIII,L.P.BoyuCapitalGeneralPartnerIII,L.P.BoyuCapital General Partner III, L.P.Boyu Capital General Partner III, Ltd.Boyu Capital GeneralPartnerIII,Ltd.BoyuCapitalGroupHoldingsLtd.BoyuCapitalGroupHoldingsLtd.XYXYHoldings Ltd.Boyu Group, LLCXYXY Holdings Ltd.100% BoyuCapitalFundIII,L.P.BoyuCapitalGeneralPartnerIII,L.P.BoyuCapitalGeneral Partner III, Ltd.Boyu Capital Group Holdings Ltd.Boyu Group, LLCXYXY Holdings Ltd.Booming Passion Limited 202412312024123125 3.25%25%25%25% 4.5%10%40%45% 2.25%202291725%202391725%202491725%2025917 3.202271320237132024713 4.25%25%25%25% 5.5%202191710%202191740%202191745%2021917 7.5%10%40%45% 9.202391202491202591 13.1.03 20241231 GraceHuiTang Zhi Hong 2023 ZhiHongGregg Huber AltonGregg Huber Alton 20241231 1. 3.2 3. 2 0 2 41 23 19 0 , 3 4 8 , 0 0 02 0 2 35,432,000179,710,0002023267,018,00017 257,325,0002023273,029,000179,710,0002023191,233,00077,126,00020236,011,000489,000202375,785,000 11. (iii)20241231VBI(i)VBIBRII-179(VBI-2601)BRII-179 (VBI-2601)PreHevbri®(ii)BRII-179(iii)FerringFerring(iv)20241231VBI-1901VBIFerringVBICda騰盛博藥VBI-1901VBI-1901VBI-1901(v)20241231RehovotRehovot(A)SciVac(i)Rehovot(ii)Rehovot(iii)Rehovot(iv)Rehovot(v)BRII-179(VBI-2601)(vi)(vii)Rehovot(viii)(B)RehovotRehovotRehovot202412312,500,00017,971,0004%12,500,00089,855,000VBIVBIK2HV2024730VBI202488VBI (i)(25%)(ii)(5%)(10%)(40%)(45%)(iii)(33.3%)(iv) 25. 25. 20231231– HR IND MAC MARCH C3 MDR/XDR NCE NDA NRTTI PK 2021630 0.00001