5,000,000 Shares of Class A Common Stock This prospectus supplement amends and supplements the prospectus dated May 4, 2026 (as supplemented or amended fromtime to time, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (No. 333-295274). This prospectus supplement is being filed to update and supplement the information in the Prospectus with the informationcontained in our Current Report on Form 8-K, filed with the Securities and Exchange Commission on July 17, 2026 (the “CurrentReport”). Accordingly, we have attached the Current Report to this prospectus supplement. This prospectus supplement updates and supplements the information in the Prospectus and is not complete without, and maynot be delivered or utilized except in combination with, the Prospectus, including any amendments or supplements thereto. Thisprospectus supplement should be read in conjunction with the Prospectus and if there is any inconsistency between the information inthe Prospectus and this prospectus supplement, you should rely on the information in this prospectus supplement. Our Class A common stock is traded on the New York Stock Exchange (“NYSE”) under the symbol “SPIR.” On July 16‚ 2026,the last quoted sale price for our Class A common stock as reported on NYSE was $12.15 per share. Investing in our securities involves a high degree of risk. Before buying any securities, you should carefully read thediscussion of the risks of investing in our securities in the section titled “Risk Factors” beginning on page 5 of the Prospectus. You should rely only on the information contained in the Prospectus, this prospectus supplement and any otherprospectus supplement or amendment hereto. We have not authorized anyone to provide you with different information. NEITHER THE SECURITIES AND EXCHANGE COMMISSION NOR ANY STATE SECURITIES COMMISSIONHAS APPROVED OR DISAPPROVED OF THESE SECURITIES OR DETERMINED IF THIS PROSPECTUS ISTRUTHFUL OR COMPLETE. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE. The date of this prospectus is July 17, 2026 UNITED STATESSECURITIES AND EXCHANGE COMMISSIONWASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 13, 2026 SPIRE GLOBAL, INC. (Exact name of registrant as specified in its charter) Delaware(State or other jurisdictionof incorporation) (Commission File Number) 8000 Towers Crescent DriveSuite 1100Vienna, Virginia(Address of principal executive offices) 22182(Zip code) Registrant’s telephone number, including area code:(202)301-5127 Not Applicable(Former name or former address, if changed since last report) Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrantunder any of the following provisions: ☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) ☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) ☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) ☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) Securities registered pursuant to Section 12(b) of the Act: Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933(§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter). Emerging growth company☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period forcomplying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.☐ Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; CompensatoryArrangements of Certain Officers. On July 13, 2026, the Board of Directors (the “Board”) of Spire Global, Inc. (the “Company”) approved, effective on August 3, 2026,the appointment of Eric Mellinger as Chief Commercial Officer of the Company. Mr. Mellinger, age 61, most recently served as theVice President for Business Development & Growth Leader, Defense & Space Sector, at Mantech International Corporation, atechnology company (“Mantech”), since April 2025.Previously, Mr. Mellinger served in multiple positions at Mantech, includingSenior Executive Director for Business Development, Defense Sector, from January 2024 to April 2025; Executive Director forBusiness Development, Defense Sector, from April 2022 to January 2024; and Director for Business Development, from January2019 to April 2022. There are no arrangements or understandings between Mr. Mellinger and any other persons pursuant to which he was appointed asChief Commercial Officer. There are no family relationships between Mr. Mellinge