5,000,000 Shares of Class A Common Stock This prospectus supplement amends and supplements the prospectus dated May 4, 2026 (as supplemented or amended from time to time, the “Prospectus”), which forms apart of our Registration Statement on Form S-1 (No. 333-295274). This prospectus supplement is being filed to update and supplement the information in the Prospectus with the information contained in our Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on May 13, 2026 (the “Quarterly Report”). Accordingly, we have attached the Quarterly Report to this prospectussupplement. This prospectus supplement updates and supplements the information in the Prospectus and is not complete without, and may not be delivered or utilized except incombination with, the Prospectus, including any amendments or supplements thereto. This prospectus supplement should be read in conjunction with the Prospectus and if thereis any inconsistency between the information in the Prospectus and this prospectus supplement, you should rely on the information in this prospectus supplement. Our Class A common stock is traded on the New York Stock Exchange (“NYSE”) under the symbol “SPIR.” On May 13 2026, the last quoted sale price for our Class Acommon stock as reported on NYSE was $18.37 per share. You should rely only on the information contained in the Prospectus, this prospectus supplement and any other prospectus supplement or amendment hereto.We have not authorized anyone to provide you with different information. NEITHER THE SECURITIES AND EXCHANGE COMMISSION NOR ANY STATE SECURITIES COMMISSION HAS APPROVED OR DISAPPROVEDOF THESE SECURITIES OR DETERMINED IF THIS PROSPECTUS IS TRUTHFUL OR COMPLETE. ANY REPRESENTATION TO THE CONTRARY IS ACRIMINAL OFFENSE. The date of this prospectus is May 14, 2026 UNITED STATES SECURITIES AND EXCHANGE COMMISSIONWASHINGTON, DC 20549 OR SPIRE GLOBAL, INC. (Exact Name of Registrant as Specified in its Charter) 8000 Towers Crescent DriveSuite 1100Vienna, Virginia 22182(Address of principal executive offices) (Zip Code)(202) 301-5127(Registrant’s telephone number, including area code) Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.Yes☒No☐ of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).Yes☒No☐Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growthcompany. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act. Large accelerated filer☐Non-accelerated filer☒Emerging growth company☐ Accelerated filerSmaller reporting company If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financialaccounting standards provided pursuant to Section 13(a) of the Exchange Act.☐Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).Yes☐No☒The registrant had outstanding 38,711,549 shares of Class A common stock and 1,507,325 shares of Class B common stock as of May 11, 2026. Table of Contents FINANCIAL INFORMATION PART I. Item 1. Unaudited Condensed Consolidated Financial StatementsCondensed Consolidated Balance SheetsCondensed Consolidated Statements of OperationsCondensed Consolidated Statements of Comprehensive LossCondensed Consolidated Statements of Changes in Stockholders’ EquityCondensed Consolidated Statements of Cash FlowsNotes to Unaudited Condensed Consolidated Financial StatementsManagement’s Discussion and Analysis of Financial Condition and Results of OperationsQuantitative and Qualitative Disclosures About Market RiskControls and Procedures Item 2.Item 3.Item 4. OTHER INFORMATION PART II. Legal ProceedingsRisk FactorsUnregistered Sales of Equity Securities and Use of ProceedsDefaults Upon Senior SecuritiesMine Safety DisclosuresOther InformationExhibits Item 1.Item 1A.Item 2.Item 3.Item 4.Item 5.Item 6.Signatures SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS This Quarterly Report on Form 10-Q contains forward-looking statements within the meaning of the federal securities laws, which statements involve substantial risksand uncertainties. Forward-looking statements generally relate to future events or our future financial or operating performance. In some cases, you can identify forward-looking statements because they contain words such as “may,” “will,” “should,” “expect,” “plan,” “anticipate




