Amazon.com, Inc. C$1,250,000,000 3.400% NOTES DUE 2029C$2,500,000,000 3.700% NOTES DUE 2031C$2,000,000,000 4.000% NOTES DUE 2033C$3,500,000,000 4.350% NOTES DUE 2036C$4,750,000,000 5.000% NOTES DUE 2056 Amazon.com, Inc. is offering C$1,250,000,000 of our 3.400% notes due 2029 (the “2029 notes”), C$2,500,000,000 of our 3.700% notes due 2031 (the “2031 notes”),C$2,000,000,000 of our 4.000% notes due 2033 (the “2033 notes”), C$3,500,000,000 of our 4.350% notes due 2036 (the “2036 notes”), and C$4,750,000,000 of our5.000% notes due 2056 (the “2056 notes” and, together with the 2029 notes, the 2031 notes, the 2033 notes, and the 2036 notes, the “notes”). The 2029 notes will bearinterest at a rate of 3.400% per annum. The 2031 notes will bear interest at a rate of 3.700% per annum. The 2033 notes will bear interest at a rate of 4.000% perannum. The 2036 notes will bear interest at a rate of 4.350% per annum. The 2056 notes will bear interest at a rate of 5.000% per annum. We will pay interest semi-annually in arrears on the notes on June 12 and December 12 of each year, beginning on December 12, 2026. The 2029 notes will mature on June 12, 2029. The 2031notes will mature on June 12, 2031. The 2033 notes will mature on June 12, 2033. The 2036 notes will mature on June 12, 2036. The 2056 notes will mature on June 12,2056. We may redeem some or all of any series of notes at any time at the applicable redemption prices as described under “Description of the Notes — OptionalRedemption.” We may redeem any series of notes in whole, but not in part, at any time at our option in the event of certain changes in the tax laws of a relevant TaxJurisdiction (as defined herein) that would require us to pay additional amounts as described under “Description of the Notes — Redemption for Tax Reasons.” Thenotes are senior unsecured obligations and will rank equally with all of our other senior unsecured indebtedness from time to time outstanding. There is no sinkingfund for the notes. The notes are not, and are not expected to be, listed on any securities exchange or any automated dealer quotation system. Neither the Securities and Exchange Commission (the “SEC”), any state securities commission, nor any other securities regulatory authority in any jurisdictionhas approved or disapproved of these securities or determined if this prospectus supplement or the prospectus to which it relates is truthful or complete. Anyrepresentation to the contrary is a criminal offense. The underwriters expect to deliver the notes on or about June 12, 2026 only in registered book-entry form and deposited in global form through the facilities ofCDS Clearing and Depository Services Inc. (“CDS”) for the accounts of its participants. Investors may hold their notes outside Canada through ClearstreamBanking, S.A. (“Clearstream”) or Euroclear Bank S.A./N.V. (“Euroclear”), as operator of the Euroclear System. Under Rule15c6-1 under the SecuritiesExchange Act of 1934, as amended (the “Exchange Act”), trades in the secondary market are generally required to settle in one business day, unless the parties toany such trade expressly agree otherwise. Accordingly, purchasers who wish to trade notes on any day prior to the business date before delivery will be required,by virtue of the fact that the notes initially settle in T+4, to specify an alternate settlement arrangement at the time of any such trade to prevent a failedsettlement and should consult their own advisors. See “Underwriting.” June 8, 2026 TABLE OF CONTENTS Prospectus PageS-iiS-iiS-iiiS-1S-7S-12S-13S-24S-30S-35S-35S-36PageAbout this Prospectus1Where You Can Find More Information1Incorporation by Reference2Special Note Regarding Forward-LookingStatements3About the Registrant3Risk Factors3Use of Proceeds4Description of Debt Securities4Description of Common Stock15Description of Other Securities16Plan of Distribution17Validity of the Securities18Experts18 About this Prospectus SupplementWhere You Can Find More InformationForward-Looking StatementsSummaryRisk Factors Underwriting Validity of the Notes We have not, and the underwriters have not, authorized anyone to provide you with any additionalinformation or any information that is different from that contained in or incorporated by reference into thisprospectus supplement, the accompanying prospectus, and any free writing prospectus provided in connectionwith this offering. We take no responsibility for, and can provide no assurance as to the reliability of, any otherinformation that others may give you. We are not, and the underwriters are not, making an offer of thesesecurities or soliciting an offer to buy these securities in any jurisdiction where the offer is not permitted. Theinformation contained in or incorporated by reference into this document is accurate only as of the date of thisdocument, unless the information specifically indicates that another date applies. Unless otherwise indicated or the context otherwise requires, re