方达控股：全年业绩公告截至2025年12月31日止年度

FRONTAGE HOLDINGS CORPORATION* 1521 (1) (2) 2024 0.00330.0004 20251231 1. 20184162019530 Cricket Square, Hutchins Drive,P.O. Box 2681, Grand Cayman, KY1-1111 Cayman Islands700 Pennsylvania Drive, Exton, PA 19341, USA33191920 2. 202511 202511 21 3. 4. ADMEAPI (i)(ii)(iii) 15(i)(ii) 5. 8 202512 31 20252024123110% 6. 7. 8. 9. 116,155125,527 10. 279(1,993) 4,8252,125 2025123126.41%202424.66%20172017122220172025123120241231 BRI Biopharmaceutical Research, Inc.BRICCPC27% Nucro-Technics, Inc.NucroCCPC26.5% 25% 202011202311202315% 202212202512202515% 70%202012202310202315% 20252024123116.5%20183212017720183282,000,0008.25%2,000,00016.5%201841 202520241231 11. (i) 62,53359,828 6,3053,794 1,3072,848 72,20669,091 3090 909118018111 13. 14. 202512310.02%3.5%20240.02%4.33% 300,000 20251231392,0002024381,00020251231392,0002024381,000 2025123124,0003,000202426,0004,000 15. 3090 16. 202518,863,000202420,295,000 17. 622,174,00088,518,0002024510,000,00070,948,000211,061,00030,028,0002024177,344,00024,670,00020251231 2022531Frontage Labs2023728Frontage Labs54,000,0002025123120,500,000202435,000,000Frontage Labs 2022722Frontage LabsFrontage Labs49,000,0002025123125,150,000202436,000,000Frontage LabsFrontageLabs 20251231362,275,00051,541,0002024304,436,00042,351,00033,500,000202419,000,000 18. 0.00001 2024112024123120251120251231 : (a)20251231202436,179,00020242,312,00020249,530,000 (b)2024123163,100,00015,122,0001,00015,121,00020251231 19. 20. 20251010III270,000,00038,413,000 2026332025101020261720263320251215 2025 2025CRDMO AIAIAIQCQAAI 20241231254.90.7%20251231256.720251231433.720241231390.611.0% 2025922.750.10%12026257.78.3%2 2025546,300CRDMO(9)(GMP)(2)(2)(5)(2)(3)202510GMPIIIPPQ 2025AI(RFI)QCQAAI 2025 • -14 PDM IIINDA800APIGMP2026 • IDBSELNIEBSWatson LIMSStudyDocAI IHC(IF)RNARNASeqWESRNAscRNA-seq Frontage Europe, S.r.l.20252025GLPGCP 2025FDADEAISO/IEC APIJefferies Group LLC7202532%2023202421%3 2025 • siRNA CAR-TNHPTCM GMP2025720258CNAS • mRNA 25% Alamar NULISA HT-Argo2025 20251231(13) •(4)•(2)•(1)•(1)•(1)•(1)•(1)•(1)•(1) 20251231(10) •(4)•(3)•(1)•(2) SOPSOP F D AD E ACNSCPHAC( C L I A / C A P )D O HAAALACUSDA NMPA Frontage LabsZenQMSSOPKPI (SDWAN)SDWANSDWANGDPRISO 27001NetSuiteSalesforce SOPUSDAFDA 20251027045,169,326100% (i)1425%100%(ii)14A5%2025101020251215 20251231 202617202633 20251231 2026 20241231254.90.7%20251231256.7 20241231198.20.3%20251231197.720241231403.556.74.4%20251231421.259.0 2024123137.215.3%2025123142.92025123116.7%2024123114.6% 2024123152.58.8%2025123157.12025123122.3%2024123120.6% 20241231185.11.3%20251231187.5 2024123169.80.9%2025123169.22024123127.4%2025123127.0%2024123129.3%2025123128.5%2024123120.7%2025123121.9% 202412314.334.9%202512312.8 202412310.2202512311.5 202412318.59.4%202512317.7 2024123147.116.8%2025123139.22024123135.114.2%2025123130.1 (i)(ii) 202412315.623.2%202512314.3 202412319.620.8%202512317.6 202412312.1128.6%202512314.8 202512316.8202412310.6202512312.6%202412310.2%20241231 2024123113.218.9%2025123115.7202512316.1%202412315.2%20251231 42024123150.08.0%2025123154.02025123121.1%2024123119.6% 52024123154.03.3%2025123155.82024123121.2%2025123121.7% 202412310.0004202512310.0034202412310.0004202512310.0033 202512310.0078202412310.006618.2%202512310.0078202412310.0066 4(i)(ii)(iii) 5 2025123145.32024123154.316.6% 2025123123.22024123130.022.7% 2024123169.14.5%2025123172.2 2024123119.33.6%2025123118.6 8.3% 2025123136.32024123144.1 2025123111.72024123125.954.8% 2025123175.72024123195.7202512312.65%6.09%45.7211.130.0 2025123151.92024123158.7 20251231 100%202512312024123125.4%33.0% 202512311,5238456781,32120285%535 20251231107.120241231114.6 20182021 2024 202662 202652720266220266220265261617 2025123120251231 2202563020251231202571202571 20252025 (www.hkexnews.hk)(www.frontagelab.com) C3 20082015 * 2026330 WentaoZhangZhongping LinYin Zhuan *