Guardant Health Inc 2026年季度报告

(Mark One)☒QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGEACT OF 1934 For the quarterly period ended March31, 2026OR ☐TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGEACT OF 1934 For the transition period fromtoCommission File Number: 001-38683_____________________ GUARDANT HEALTH, INC. 45-4139254(I.R.S. EmployerIdentification No.) (State or other jurisdiction ofincorporation or organization) 3100 Hanover StreetPalo Alto, California, 94304Registrant’s telephone number, including area code: (855) 698-8887_______________ Securitiesregistered pursuant to Section 12(b) of the Act: Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the SecuritiesExchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2)has been subject to such filing requirements for the past 90 days.Yes☒No☐ Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuantto Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant wasrequired to submit such files).Yes☒No☐ Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reportingcompany, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,”and “emerging growth company” in Rule 12b-2 of the Exchange Act. If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period forcomplying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.☐ Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).Yes☐No☒ As of May1, 2026, the registrant had 132,599,929 shares of common stock, $0.00001 par value per share, outstanding. GUARDANT HEALTH, INC.FORM 10-Q TABLE OF CONTENTS PART I – FINANCIAL INFORMATION PageItem 1.Unaudited Condensed Consolidated Financial Statements3Condensed Consolidated Balance Sheets3Condensed Consolidated Statements of Operations4Condensed Consolidated Statements of Comprehensive Loss5Condensed Consolidated Statements of Stockholders’ Deficit6Condensed Consolidated Statements of Cash Flows7Notes to the Unaudited Condensed Consolidated Financial Statements8Item 2.Management’s Discussion and Analysis of Financial Condition and Results of Operations36Item 3.Quantitative and Qualitative Disclosures About Market Risk46Item 4.Controls and Procedures47 Item 1.Legal Proceedings48Item 1A.Risk Factors48Item 2.Unregistered Sales of Equity Securities and Use of Proceeds48Item 3.Defaults Upon Senior Securities48Item 4.Mine Safety Disclosures48Item 5.Other Information48Item 6.Exhibits49Signatures50 FORWARD-LOOKING STATEMENTS This Quarterly Report on Form 10-Q, including the section titled “Management’s Discussion and Analysis of Financial Condition and Resultsof Operations,” contains forward-looking statements regarding future events and our future results that are based on our current expectations,estimates, forecasts and projections as well as the current beliefs and assumptions of our management, including about our business, ourfinancial condition, our results of operations, our cash flows, and the industry and environment in which we operate. Statements that includewords such as “believe,” “may,” “will,” “estimate,” “continue,” “anticipate,” “would,” “could,” “should,” “intend” and “expect,” variations ofthese words, and similar expressions, are intended to identify forward-looking statements. These forward-looking statements speak only as ofthe date of this Quarterly Report on Form 10-Q and are subject to risks, uncertainties and assumptions that are difficult to predict. Therefore,actual results may differ materially and adversely from those expressed in any forward-looking statements. Factors that might cause orcontribute to such differences include, but are not limited to, those discussed in Part I, Item 1A,“Risk Factors” and elsewhere in our AnnualReport on Form 10-K for the year ended December31, 2025, in Part II, Item 1A, “Risk Factors” and elsewhere in this Quarterly Report onForm 10-Q, and in other reports we file with the U.S. Securities and Exchange Commission, or the SEC. While forward-looking statements arebased on the reasonable expectations of our management at the time that they are made, you should not rely on them. We undertake noobligation to revise or update publicly any forward-looking statements for any reason, whether as a result of new information, future events orotherwise, except as may be required by law. Each of the terms the “Company,” “we,” “our,” “us” and similar terms