归创通桥年报 2025

2478104046788198103104106107108188 22 270 270 33191928 128 9925-28 H1617 9984 H02190 432 www.zyloxtb.com 1811 20252024 1 20251,057.5202435.1%244.42024143.7% 202471.6%202572.1%28.0%50.3%32.8%115.5% 2 2025+115.5% 20261Optimed++ 3 2025AI202511Mammoth61110 OtterOrca 4 20253,300110 2026 (i)(ii)(iii)(iv) 202512 31UltraFreePTA(UltraFree DCB) H I. 2025 1,057.52024782.535.1%64.1%35.9% 2025202428.0%(i)30(ii)(iii) 2025202450.3%(i)UltraFreePTA(UltraFreeDCB)PhoenixSwan(ii)PenguinUnicorn 202471.6%202572.1% 2025244.42024143.7%273.12024124.0120.2% 1. 2025202535.1%6120203,3001,100,000 2. MarketsandMarketsGrand View Research10012%-15%7015%-20% (1) 202548.62024115.5%7TOP 10402980 CEGPOsAsklepiosSANA 3450FDA (2) 20261OptimedOptimed70 Optimed 3. 2025 —Mammoth 12F-18F2019150203033050%2025 — DFTDrawn Filled Tube20%2025 —Orca 4,0001/3OrcaTPU+108mm202622027 —Otter ++ 50%70%202622027 — 40%~60%2025122027 4. 244.4 202572.1%202471.6% 202422.3%202518.4% 2025246.82024233.25.8% 7961CE(UAE) 3450 302027 (CRD)(BGC)BADDASSBADDASSBAlloon guide with large bore Distal accesscatheter with Dual Aspiration with Stent-retriever as Standard approach CRD BADDASSCRD CRD 2025 DFTDrawn Filled Tube(DFT)420%50mm75mm Unicorn (bAVM)(DAVF)(bAVM)bAVM5%4525%–35%(DAVF)2026 90% 30%-50%20191,73020302,7902027 40%–60% 10%–30%2025122027 31202710 PTA —UltraFreePTA(UltraFree DCB) UltraFree DCB202011202010CE2021UltraFree DCB —UberVanaDCB DCBUberVanaDCB —UltraFree BTK DCB300mmRCT6300% Swan 6F512020 Octoplus ZYLOX Octoplus(PE)(DVT) Penguin 420241 Unicorn Unicorn3–0Unicorn5F–22F8F 201510.75201927.432030378.21Unicorn20245 Eagle EagleEagleEyeEagleNest 20251 Mammoth (12F–18F)3.5 2019150203033050% KINGKONG RBP 40 atm60 atm1% 40 atmFDA OCTCTO 20243Avinger Inc.AvingerAvinger Inc.(i)PantherisISR(ii)Tigereye ST(iii)LightBox 3OCT AIOCTOCT OCT 2019PAD4,95020306,230PAD80% Pantheris(OCT)PAD(MAE)Pantheris(ISR)IDEVISION StudyINSIGHT Study, Pantheris DCBDCB202492025 Pantheris OCT OCT Tigereye ST(CTO)OCTCTO202411 Tigereye ST LightBox 3 OCT LightBox 3 OCTPantherisTigereye ST(OCT)CTO OCTLightBoxXPADOCT LightBox 3 OCT 4,000(DCB)leave nothing behind Orca Orca4,0001/3 OrcaTPU+108mm 20262 Orca Otter ++ 50%70%20262 Otter 4,00050% 2026FDA II. 1,057.52024782.535.1%64.1%35.9% 202428.0%(i)30(ii)(iii) 2025202450.3%(i)UltraFreePTA(UltraFreeDCB)PhoenixSwan(ii)PenguinUnicorn 202512 31294.6202412 31222.632.3%(i)20241231(ii) 202412 31559.936.3%20251231762.9202412 3171.6%202512 3172.1%(i)(ii) 202512 31246.8202412 31233.25.8%202434.9202549.1 202512 31194.7202412 31174.711.4%202412 3122.3%18.4%(i)(ii)(iii) 202512 31121.2202412 3191.033.1%202412 3111.6%202512 3111.5% 202512 311.2202412 311.414.7% 202512 3129.4202412 3120.345.1%2025 46.8202412 3143.62025 202512 3155.1202412 3165.22025 202512 317.6202412 31 (1) (1)H2025 202412312,509.6202512 312,600.2321.0202512 31579.6202412 31418.138.6%202512 311,854.7202412 311,926.1202512 31166.0202412 31165.4 202512 3160.0202412 3187.0 202512 3160.02.11% 202412 312.93%202512 311.97% 202512 311,621.0202412 311,194.935.7% 202512 31 202512 31 202512 31111.2 202512 31 202512 31 202512 31925202412 31875 202512 313.0279.1202412 3112.8158.7202512 31 III. 3450 Optimed (CRD)PenguinMammothOrcaOtterOCT 5920121120121120213 291996720026Guilford Pharmaceuticals Inc.4523CordisCorporationCardinalHealth2002720118 1988619975• 56201672018320213 1995720101020111201292012102014920141020166 1992719957200312 482019120213201622018 20157Medtronic PLCMDT20092013Mystic Pharmaceuticals LimitedInternational Biomedical Ltd 19996200242007820189 3820225 20158CS Capital Co., Ltd.201182015320181020166EpimAb Biotherapeutics Inc.20213 2009201120156 5720201020213 2020199OrbiMedAdvisorsLLCOrbiMed Advisors LLCUBS AG 20204202172138201762019101530 1991519975•2000920029 5620213 19971219971220001220001220041220041220188 2016320106201120101020176 1992719978 妘6220213 20041119867199912 20011200532005420146 2022268829920204600724201572021560113720176202150115820235600177 1986719976200411 512009(eWEAR)2021 20142019 19971999200420042008200820122013 38202311 172021420185202142014201820112014 2011 4620225 202112025820166202012Edwards Lifesciences China20062016 2002 3720213 20188202112010720188300529 20196ISO 90012015 ISO134852016 20106 59 4720211 1620183SoucheHolding2016112018320097201610Bank of America Merrill Lynch 200172005320096 201211 620213 220217 5H02190 202512 3137 202512 31103187 202512 310.2274.2202520266 1820266 2H20263 17 7 13.91C2 20253 31 20253 3113.51(2) 4045 3.13 (a)(b) 3.25 38 1818 18 202512 31XV(a)XV78(b)352(c) (1)202512 317,781,257336,350,744HL (2)WEA Enterprises, LLCWEA20211 21II 202512 318,141,222H1,015,1983,750,196H568,2947,353,613H1,095,8577,488,498H957,709 (3)40.0%49.3%8,141,222H1,015,1983,750,196H568,294(4)(i)38,719,796H(ii)H400,000H20253,600,000H(5)(i)479,427H(ii)H200,000H2025