GLOBAL INFLUENZA SURVEILLANCE AND RESPONSE SYSTEM (GISRS) Co-circulationInfluenza SUMMARY Globally, influenza activity remained stable and positivity was just above 15% in week 6 2026. SARS-CoV-2 activity remained low overall. Influenzapredominated and positivity was around 15% in the northern hemisphere temperate and subtropical areas and the tropical areas. In the southern hemisphere qInfluenza Globally, influenza detections continued to decline in week 6. Influenza A viruses were predominant among influenza detections, with a slight increase In the northern hemisphere, influenza percent positivity was elevated (>10%) in countries in North America, Western Africa, Western, Southern andSouth-East Asia. Percent positivity was over 30% in countries in Central America and the Caribbean, Tropical South America, Northern Africa, In the southern hemisphere, influenza activity remained low overall although elevated positivity (>10%) was reported in single countries in TemperateSouth America and Eastern Africa and two countries in Tropical South America. Percent positivity was over 30% in a single country in Oceania. No qSARS-CoV-2 Globally, SARS-CoV-2 positivity remained stable and low, with single countries reporting elevated positivity (>10%) in Temperate South America,South West and Northern Europe. Small increases in activity were reported in single countries in South West and Northern Europe. [Figures 7 and 8] Globally, RSV positivity remained stable and low, with a few countries reporting elevated positivity (>10%) in Central America and the Caribbean,Northern Africa, South West and Northern Europe and Western Asia. Small increases in activity were reported in a few countries in Central Americaand the Caribbean and Northern Europe and in single countries in Northern Africa, South West and Eastern Europe and Western Asia. [Figures 9 The severity assessments here are reported from countries, areas and territories. Assessments for transmissibility can be reported based on syndromicparameters and/or influenza-specific parameters. In the northern hemisphere temperate and subtropical areas, influenza-specific transmissibility wasreported as low (1) and moderate (1); transmissibility using syndromic data was reported as below seasonal threshold (12), low (8), moderate (12) and Co-circulation of influenza and SARS-CoV-2 1b) Weekly numbers of influenza andSARS-CoV-2 virus specimens tested and 1d) Weekly numbers of influenza andSARS-CoV-2 virus specimens tested and Influenza SARS-CoV-2 Respiratory syncytial virus Severity assessment Additional information Data and methods The data presented in this report originates from virologic surveillance conducted by countries, areas, and territories (CATs) and submitted to WHO FluNet through participation orcollaboration with the Global Influenza Surveillance and Response System (GISRS). These CATs employ diverse methodologies to monitor respiratory virus activity, which may resultin variations between this report and other surveillance summaries published elsewhere. To assess trends, the proportion of specimens tested positive for influenza or SARS-CoV-2 was smoothed over a 3-weeks period. This analysis includes only countries that tested 10 ormore specimens in at least two of the three weeks. Weekly changes in the smoothed positivity rate for each virus were calculated as absolute differences from the previous week. These The influenza transmission zones map is based on data aggregated over a 3-weeks period, moving backward from the current week until a minimum threshold of 100 tested samples isreached within each influenza transmission zone. Pie charts are displayed on the map only if the total percent positivity in a influenza transmission zones map is 20% or higher. Alltrend analyses are based on ISO 8601 calendar week numbering. Severity assessments: The severity assessments here are reported from countries, areas and territories.WHO’s Pandemic influenza severity assessment (PISA): a WHO guide to assess the severityof influenza in seasonal epidemics and pandemics, 2nd ed outlines the methods for which countries, areas and territories can derive these severity assessments. Assessments for Countries, areas and territories may not provide assessments year-round. The assessments may be revised over time if there is retrospective/delayed reporting or updating of previouslyreported data. These assessments are made in the context of historical data from the country making the assessment and thus are not comparable between countries. Assessments may The quality and consistency of influenza surveillance data are influenced by changes in health seeking behaviours, routines in sentinel and non-sentinel sites, national testing prioritiesand capacities, and public health and social measures implementation. Differences between information products published by WHO, national public health authorities and othersources are to be expected and must be interpreted