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Washington, D.C. 20549FORM 13F FORM 13F COVER PAGE 12-31-2025 Amendment Number: Check here if Amendment This Amendment (Check only one.): Institutional Investment Manager Filing this Report: SIMMONS FIRST NATIONAL CORP501 MAIN STREETPINE BLUFF,AR71601028-0480128-04801 Name:Address: Form 13F File Number:CRD Number (if applicable):SEC File Number (if applicable): The institutional investment manager filing this report and the person by whom it is signed hereby represent that theperson signing the report is authorized to submit it, that all information contained herein is true, correct andcomplete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered Person Signing this Report on Behalf of Reporting Manager: DANIEL HOBBSEVP Chief Financial Officer501-377-7408 Name:Title:Phone: Signature, Place, and Date of Signing: /s/Daniel Hobbs Report Type (Check only one.): 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.)X13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reportingmanager(s).)13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this reportand a portion are reported by other reporting manager(s).)