美因基因年度报告2024

股份代號: 6667(於開曼群島註冊成立的有限公司) 年度報告 2 689102032405990125131132134135137 20261 27 20246282024628 1 528 202572197927 20258 4779 202451818 20246282024628 (1)20241 17 Third Floor, Century YardCricket Square, P.O. Box 902Grand Cayman, KY1-1103Cayman Islands 1617 401 6667 528 www.megagenomics.cn Appleby Global Services (Cayman) Limited71 Fort StreetPO Box 500George TownGrand Cayman KY1-1106Cayman Islands 20241231 2024 164.220238.5%45.0202315.057.2 ESG 20261 30 2024123123 2021123120202022610 202412 3111494 • •Septin9RNF180/Septin9 •Plus (i)(ii) IVD (i)2025(ii)ApoE2025(iii)BRCA1/BRCA2 (i)(ii)(iii)(iv)(v) ApoE ApoEqPCRApoEApoEApoEϵ4 2025 qPCRMTHFR 2025 miRNA1,500 RT-qPCRNGSNGSLDT RT-qPCR2027 DNA 2024123131,500 qPCRNGS NGSLDT90% qPCR2027 DNA 2024123131,500 qPCRNGS NGSLDT90% qPCR2027 BRCA1/BRCA2 BRCA1/BRCA2PCR 20241231 cfDNADNA20241231 2016 202412315060 65% IVDIVD IVDCROIVD 20241231 IVD CDMOCDMOIVDPCR CRO PCRqPCRNGSPCR IVDNMPAcfDNANMPAApoEIVDBRCA1/BRCA2 PCRqPCRNGSPCR50,000 880PCR2022 164.22023151.38.5%45.0202330.050.0% 340 20241231164.22023151.312.98.5%20241231159.64.6 20241231119.3202388.335.2%116.52.8 2024123172.7%202358.4%14.32024123173.0%202352.9%20.161.1%202372.1%11 2024123145.027.4%202330.019.9%202450.0%7.5 202020300.8%11.6% 65%19.214.3%20241231114945060 340 IVD 20241231ApoENMPA2025 NMPA2025 31,500 BRCA1/BRCA2 20241231 cfDNADNA20241231 202312312024 •20241231159.62023108.447.3% •202412314.6202342.989.2% 2023123163.028.8%202444.9 20232024123188.3119.358.4%72.7% 2023123157.32024116.52023123152.9%202473.0% 2023123131.020242.8 2023123112.020246.8 2023202412311.01.1 202312 3130.7202436.6 202312 3122.4202419.2 202312312024123122.122.9 202312 3111.6202412 317.3 202312310.320240.5 202312311.120241.7202392024 202312316.120248.6 2023123130.0202445.0 2022622 57.2 6.6 91.8 20231231518.35.4%20241231490.3 202312312024123125.913.7 2024123120.7202322.62.018.7 2320241231 123120231231 202412314.7%202312 316.1%1.4 (1)(2)(3) 20241231 20241231 20241231 202412 3133.2202334.7 20241231 202412 31209 202111 19202212 2927,272,000D.20221229 20254 1 20255 23 (i) (ii) (iv) (v)13.24 (vi) 2025530 20256302025930202512 31 20257 2120255520256302025721 20251110 2026112 20241231 20214222022622 20226221811,961,800215.3153.420241231 53201615202186 23 2004 1998320068 20103002577 20152 20153 20161872612 20161120217300231 20175201912 20191201910 1993719998 2013720099 4920181202012 11202012 202132021422202186 2320076201212 20131 20171 4320171520201211202131820218617 20087201312 20141201612 20171 5202012202411620213182024116202132920214620239282021624 20066 2024117105(b) 452020112021862024117 22200311201262012720135201352018120181202011834425 20196 562021318202186 23200210 201510 20081 2015212 2014820197 201712 6 20203 6 20147 46202186 16 201956006942022 20226000625202210600977 2002720077 47202186 162008920174201742015121520171025 2017112018630036420186201912 20186201912Crazy Maple Studio, Inc. 20201202452024520 20047201962820163.10(2) 44202186 1320119201532015720209 (1)(2)(3)(4)(5) 2006720118 44201972216 20089201778247 2017820195 2008720209 422017121912 2013620163 20163201712 20137 4120178117 20061220111 2011220177 20196 20241231 C1 20241231 20241231 12 12024117 41 202412316211 202412 31 C.5.1 2024117 20241231 3.13 20241231 20241231 (i) (ii) (iii) (iv) (v) 108 20241231 20241231 202412 31202312 312024630 20241231 20241231 20241231 20241231 757620241231 (i)(ii)(iii)(iv)(v) (i)(ii)(iii) •••18•• 20241231 A.2.1 20241231 (i)(ii)(iii) 20241231 20241231 202412311.2202412 310.9 2024628 20246 28 202412313.2915 64 21 401 528 ir@megagenomics.cn (a) (a)(b)(c)(d)(e)(f) (www.hkex.com.hk) (b) (c) (www.megagenomics.cn) (d) (e) www.tricoris.comis-enquiries@hk.tricorglobal.com298013331617 ir@megagenomics.cn401 (f) (g) ESG C2 20241120241231 ESGESGESGESGESG2022ESGESGESGESGESGESGESGESGESG ESGESGESGESG 2024ESG ESGESGESGESGESGESGESG 2024ESG2026130 1 1.1 2024123123202112312020 50,000 20241231340 1.2 1.3 ESGESGESG 1.4 ESG 1.5 19ESGESG 環境 員工 1.能源使用2.水資源使用3.廢棄物管理4.溫室氣體排放5.氣候變化 6.職業健康與安全7.職業發展與機遇8.員工福利9.童工及強制勞工10. 吸納及挽留人才11. 僱員培訓 社區 業務 12. 合規經營13. 供應鏈管理14. 投訴處理15. 反貪污16. 知識產權17. 客戶資料保障 18. 社區貢獻19. 公益投入 ESGESG 2 2.1 2.1.1 2 DB11/501-2017II50 mg/m320240.45 mg/m320230.36 mg/m3 571.722023810.892.63 2025 58.690.27 SOP-016-SYGL-2.0EHS 2025 2.2 843.742023916.983.8920233.46 18-25 2025 29120232801.3420231.06 2025 2.3 pH69(COD)500 DB11/501-2017 2.4 2.4.1 TCFDESGESG 1155 2.4.2 3 3.1 3.1.1 2 2023 3.1.2 202499.83%1.73% 3.1.3 202412312052023229 3.1.4 20241231724%202349% 7 3.2 34 2023 3.2.1 EHSEHSEHSEHS 2023 3.2.2 3.3 3.3.1 2024 14.099202311.52 9 2,88820232,6392,92620231,821 3.4 2023 4 4.1 2012023201 4.2 (ISO15189:2022)352016182021 QA 20232023 4.2.1 (CNAS)ISO1518